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Year Number of Results
1947 1
1949 1
1951 8
1952 4
1953 10
1954 4
1955 3
1956 6
1957 6
1958 1
1959 4
1960 5
1961 7
1962 6
1963 9
1964 20
1965 19
1966 20
1967 21
1968 23
1969 32
1970 30
1971 37
1972 68
1973 60
1974 51
1975 78
1976 57
1977 56
1978 67
1979 84
1980 83
1981 61
1982 83
1983 76
1984 100
1985 97
1986 109
1987 117
1988 109
1989 95
1990 127
1991 136
1992 125
1993 148
1994 124
1995 177
1996 148
1997 209
1998 181
1999 209
2000 234
2001 215
2002 200
2003 272
2004 300
2005 281
2006 374
2007 490
2008 702
2009 694
2010 630
2011 685
2012 679
2013 717
2014 780
2015 925
2016 886
2017 838
2018 905
2019 923
2020 1221
2021 1339
2022 1361
2023 1154
2024 468

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Page 1
Prolidase activity in women with polycystic ovarian syndrome undergoing assisted conception.
Erdoğan K, Utlu Özen E, Kahyaoğlu İ, Neselioglu S, Erel Ö, Akar S, Özdemir Ö, Ercan CM, Engin Üstün Y. Erdoğan K, et al. J Obstet Gynaecol. 2024 Dec;44(1):2346228. doi: 10.1080/01443615.2024.2346228. Epub 2024 Apr 26. J Obstet Gynaecol. 2024. PMID: 38973654 Free article.
Polycystic ovary syndrome (PCOS), the most prevalent endocrinopathy among reproductive-aged women, affects approximately 3-15% of this demographic. Long-term disorders such as cardiovascular disease, type 2 diabetes mellitus, obesity, and infertility are commonly as …
Polycystic ovary syndrome (PCOS), the most prevalent endocrinopathy among reproductive-aged women, affects approximately 3-15% of thi …
Telomerase activity, telomere length, and the euploidy rate of human embryos.
Longo M, Greco E, Listorti I, Varricchio MT, Litwicka K, Arrivi C, Mencacci C, Greco P. Longo M, et al. Gynecol Endocrinol. 2024 Dec;40(1):2373742. doi: 10.1080/09513590.2024.2373742. Epub 2024 Jul 1. Gynecol Endocrinol. 2024. PMID: 38946430 Free article.
Telomere length varies between cell types, with leukocyte telomere length (LTL) decreasing with age. Reduced telomerase activity has been linked to reproductive issues in females, such as low pregnancy rates and premature ovarian failure, with recent studies indicating cor …
Telomere length varies between cell types, with leukocyte telomere length (LTL) decreasing with age. Reduced telomerase activity has been li …
Effect of body mass index on progesterone level on trigger day in gonadotropin-releasing hormone antagonist cycles.
Sun Y, Zhu A. Sun Y, et al. Gynecol Endocrinol. 2024 Dec;40(1):2364892. doi: 10.1080/09513590.2024.2364892. Epub 2024 Jun 30. Gynecol Endocrinol. 2024. PMID: 38946240 Free article.
From October 2017 to April 2022, 412 in-vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) patients who were treated with GnRH-ant protocol for controlled ovarian hyperstimulation (COH) in the reproductive center of our hospital were selected as the research …
From October 2017 to April 2022, 412 in-vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) patients who were treated with GnR …
Prediction of embryo euploidy and pregnancy outcome by blastocyst morphology and development speed for women receiving single embryo transfer.
Dong K, Wu C, Hou X, Zeng Y, Luo L. Dong K, et al. J Obstet Gynaecol. 2024 Dec;44(1):2338235. doi: 10.1080/01443615.2024.2338235. Epub 2024 Apr 15. J Obstet Gynaecol. 2024. PMID: 38619096 Free article.
BACKGROUND: Selection of high-quality blastocysts is the most important factor determining the success of assisted reproductive technology. The objective of this study is to assess the values of blastocyst morphological quality and development speed for predicting euploidy …
BACKGROUND: Selection of high-quality blastocysts is the most important factor determining the success of assisted reproductive techn …
Bushen Huoxue Recipe inhibits endometrial epithelial-mesenchymal transition through the transforming growth factor-beta/nuclear factor kappa-B pathway to improve polycystic ovary syndrome-mediated infertility.
Wu H, Wu P, Zhu Y, Li J, Chen H, Zhu H. Wu H, et al. Gynecol Endocrinol. 2024 Dec;40(1):2325000. doi: 10.1080/09513590.2024.2325000. Epub 2024 Mar 13. Gynecol Endocrinol. 2024. PMID: 38477938 Free article.
OBJECTIVE: To investigate the target and mechanism of action of Bushen Huoxue Recipe (BSHX) for the treatment of infertility in polycystic ovary syndrome (PCOS), to provide a basis for the development and clinical application of herbal compounds. ...CONCLUSIONS: TGF-beta, …
OBJECTIVE: To investigate the target and mechanism of action of Bushen Huoxue Recipe (BSHX) for the treatment of infertility in polyc …
Maternal intake of paracetamol during pregnancy and biomarkers of male fecundity in young adult sons.
Laursen TQ, Ramlau-Hansen CH, Tøttenborg SS, Liew Z, Toft G, Gaml-Sørensen A, Hougaard KS, Bonde JPE, Ernst A. Laursen TQ, et al. Reprod Toxicol. 2024 Aug;127:108626. doi: 10.1016/j.reprotox.2024.108626. Epub 2024 May 28. Reprod Toxicol. 2024. PMID: 38815769 Free article.
Paracetamol is suggested to have endocrine disrupting properties possibly affecting fetal programming of reproductive health that might lead to impaired semen quality and changes in reproductive hormones. ...Outcomes included semen characteristics, self-measured tes …
Paracetamol is suggested to have endocrine disrupting properties possibly affecting fetal programming of reproductive health that mig …
Prevalence and help-seeking for infertility in a population with a low fertility rate.
Lee MC, Chien PS, Zhou Y, Yu T. Lee MC, et al. PLoS One. 2024 Jul 18;19(7):e0306572. doi: 10.1371/journal.pone.0306572. eCollection 2024. PLoS One. 2024. PMID: 39024399 Free PMC article.
We used computer-assisted telephone interviewing techniques to collect data regarding sociodemographic and reproductive characteristics. Using two approaches to defining infertility, we estimated the prevalence of infertility and the prevalence of help-seekin …
We used computer-assisted telephone interviewing techniques to collect data regarding sociodemographic and reproductive characteristi …
First-line infertility treatment in normal or subnormal sperm: Interest of a simplified pre-IMSI test.
Sigala J, Poirey S, Robert J, Pouget O, Mura T, Huberlant S, Rougier N. Sigala J, et al. PLoS One. 2024 Jul 15;19(7):e0307080. doi: 10.1371/journal.pone.0307080. eCollection 2024. PLoS One. 2024. PMID: 39008497 Free PMC article.
BACKGROUND: In the field of male infertility, when sperm is normal/subnormal, a few "add-on" routine tests can complete the basic semen examination. ...MATERIALS AND METHODS: We validated an adapted version of the MSOME analysis called the pre-IMSI test (PIT), based on vac …
BACKGROUND: In the field of male infertility, when sperm is normal/subnormal, a few "add-on" routine tests can complete the basic sem …
The efficacy of early office hysteroscopy in preventing intrauterine adhesions after abortion: a randomized controlled trial.
Tsai NC, Hsiao YY, Su YT, Lin YJ, Kung FT, Chen PH, Lan KC. Tsai NC, et al. BMC Womens Health. 2024 Jul 13;24(1):400. doi: 10.1186/s12905-024-03247-0. BMC Womens Health. 2024. PMID: 39003483 Free PMC article. Clinical Trial.
BACKGROUND: Intrauterine adhesions (IUA) are a challenging clinical problem in reproductive infertility. The most common causes are intrauterine surgery and abortions. ...
BACKGROUND: Intrauterine adhesions (IUA) are a challenging clinical problem in reproductive infertility. The most common cause …
Improvement of early miscarriage rates in women with adenomyosis via oxytocin receptor antagonist during frozen embryo transfer-a propensity score-matched study.
Lin PW, Chern CU, Li CJ, Lin PH, Tsui KH, Lin LT. Lin PW, et al. Reprod Biol Endocrinol. 2024 Jul 12;22(1):79. doi: 10.1186/s12958-024-01255-1. Reprod Biol Endocrinol. 2024. PMID: 38997744 Free PMC article.
This research aims to investigate whether administering an oxytocin receptor antagonist during a frozen embryo transfer (FET) cycle using a hormone replacement therapy (HRT) protocol can enhance in vitro fertilization (IVF) outcomes for infertile women affected by adenomyosis. ME …
This research aims to investigate whether administering an oxytocin receptor antagonist during a frozen embryo transfer (FET) cycle using a …
AXDND1 is required to balance spermatogonial commitment and for sperm tail formation in mice and humans.
Houston BJ, Nguyen J, Merriner DJ, O'Connor AE, Lopes AM, Nagirnaja L, Friedrich C, Kliesch S, Tüttelmann F, Aston KI, Conrad DF, Hobbs RM, Dunleavy JEM, O'Bryan MK. Houston BJ, et al. Cell Death Dis. 2024 Jul 12;15(7):499. doi: 10.1038/s41419-024-06874-5. Cell Death Dis. 2024. PMID: 38997255 Free PMC article.
To test this hypothesis, we produced a knockout mouse model. Axdnd1(-/-) males were sterile at all ages but presented with an evolving testis phenotype wherein they could undergo one round of histologically replete spermatogenesis followed by a rapid depletion of the semin …
To test this hypothesis, we produced a knockout mouse model. Axdnd1(-/-) males were sterile at all ages but presented with an evolvin …
Combined traditional Chinese medicine therapy for the treatment of infertility with polycystic ovary syndrome: A network meta-analysis of randomized controlled trials.
Deng YP, Zhou YL, Wei TT, He GS, Zhu ZX, Zhang SN, Liu MJ, Xue JJ, Zhang WX, Yang XG. Deng YP, et al. Medicine (Baltimore). 2024 Jul 12;103(28):e38912. doi: 10.1097/MD.0000000000038912. Medicine (Baltimore). 2024. PMID: 38996123 Free PMC article.
BACKGROUND: Polycystic ovary syndrome (PCOS) infertility has attracted great attention from researchers due to its high incidence. ...CONCLUSION: The combined TCM therapy demonstrated better efficacy for the treatment of infertility with PCOS compared to acupuncture …
BACKGROUND: Polycystic ovary syndrome (PCOS) infertility has attracted great attention from researchers due to its high incidence. .. …
Resveratrol ameliorates mitochondrial biogenesis and reproductive outcomes in women with polycystic ovary syndrome undergoing assisted reproduction: a randomized, triple-blind, placebo-controlled clinical trial.
Ardehjani NA, Agha-Hosseini M, Nashtaei MS, Khodarahmian M, Shabani M, Jabarpour M, Fereidouni F, Rastegar T, Amidi F. Ardehjani NA, et al. J Ovarian Res. 2024 Jul 10;17(1):143. doi: 10.1186/s13048-024-01470-9. J Ovarian Res. 2024. PMID: 38987824 Free PMC article. Clinical Trial.
BACKGROUND: This study was designed to examine the effect of resveratrol on mitochondrial biogenesis, oxidative stress (OS), and assisted reproductive technology (ART) outcomes in individuals with polycystic ovary syndrome (PCOS). ...
BACKGROUND: This study was designed to examine the effect of resveratrol on mitochondrial biogenesis, oxidative stress (OS), and assisted …
The construction of machine learning-based predictive models for high-quality embryo formation in poor ovarian response patients with progestin-primed ovarian stimulation.
Xiao YH, Hu YL, Lv XY, Huang LJ, Geng LH, Liao P, Ding YB, Niu CC. Xiao YH, et al. Reprod Biol Endocrinol. 2024 Jul 10;22(1):78. doi: 10.1186/s12958-024-01251-5. Reprod Biol Endocrinol. 2024. PMID: 38987797 Free PMC article.
CONCLUSION: We developed a predictive model for the formation of high-quality embryos using machine learning methods for patients with POR undergoing treatment with the PPOS protocol. This model can help infertility patients better understand the likelihood of forming high …
CONCLUSION: We developed a predictive model for the formation of high-quality embryos using machine learning methods for patients with POR u …
Depletion of placental brain-derived neurotrophic factor (BDNF) is attributed to premature ovarian insufficiency (POI) in mice offspring.
Liu B, Liu Y, Li S, Chen P, Zhang J, Feng L. Liu B, et al. J Ovarian Res. 2024 Jul 9;17(1):141. doi: 10.1186/s13048-024-01467-4. J Ovarian Res. 2024. PMID: 38982490 Free PMC article.
INTRODUCTION: Premature ovarian insufficiency (POI) is one of the causes of female infertility. Unexplained POI is increasingly affecting women in their reproductive years. ...
INTRODUCTION: Premature ovarian insufficiency (POI) is one of the causes of female infertility. Unexplained POI is increasingly affec …
Anticipating in vitro gametogenesis: Hopes and concerns for IVG among diverse stakeholders.
Le Goff A, Jeffries Hein R, Hart AN, Roberson I, Landecker HL. Le Goff A, et al. Stem Cell Reports. 2024 Jul 9;19(7):933-945. doi: 10.1016/j.stemcr.2024.05.002. Epub 2024 Jun 6. Stem Cell Reports. 2024. PMID: 38848715 Free PMC article.
We conducted focus groups and interviews with 80 individuals with lived experience of infertility and/or LGBTQ+ family formation in the US, two intersecting groups of potential IVG users. Respondents expressed hope that IVG would lead to higher reproductive success …
We conducted focus groups and interviews with 80 individuals with lived experience of infertility and/or LGBTQ+ family formation in t …
Deficiency of ValRS-m Causes Male Infertility in Drosophila melanogaster.
Duan X, Wang H, Cao Z, Su N, Wang Y, Zheng Y. Duan X, et al. Int J Mol Sci. 2024 Jul 8;25(13):7489. doi: 10.3390/ijms25137489. Int J Mol Sci. 2024. PMID: 39000597 Free PMC article.
The ValRS-m (Valyl-tRNA synthetase, mitochondrial) gene was down-regulated in ocn RNAi testes. Here, we found that ValRS-m-knockdown induced complete sterility in male flies. The depletion of ValRS-m blocked mitochondrial behavior and ATP synthesis, thus inhibiting the tra …
The ValRS-m (Valyl-tRNA synthetase, mitochondrial) gene was down-regulated in ocn RNAi testes. Here, we found that ValRS-m-knockdown induced …
The dynamic expression of YAP is essential for the development of male germ cells derived from human embryonic stem cells.
Khampang S, Lorthongpanich C, Laowtammathron C, Klaihmon P, Meesa S, Suksomboon W, Jiamvoraphong N, Kheolamai P, Luanpitpong S, Easley CA, Mahyari E, Issaragrisil S. Khampang S, et al. Sci Rep. 2024 Jul 8;14(1):15732. doi: 10.1038/s41598-024-66852-x. Sci Rep. 2024. PMID: 38977826 Free PMC article.
Modulating the level of YAP during human spermatogenesis could improve the production yield of male germ cells derived from hESCs, which could provide the optimization method for in vitro gametogenesis and gain insight into the application in the treatment of male infertility
Modulating the level of YAP during human spermatogenesis could improve the production yield of male germ cells derived from hESCs, which cou …
Harnessing Artificial Intelligence to Predict Ovarian Stimulation Outcomes in In Vitro Fertilization: Scoping Review.
AlSaad R, Abd-Alrazaq A, Choucair F, Ahmed A, Aziz S, Sheikh J. AlSaad R, et al. J Med Internet Res. 2024 Jul 5;26:e53396. doi: 10.2196/53396. J Med Internet Res. 2024. PMID: 38967964 Free article. Review.
Notably, the vast majority of studies were restricted to a single infertility clinic and exclusively relied on nonpublic data sets. CONCLUSIONS: These insights highlight an urgent need to diversify data sources and explore varied AI techniques for improved prediction accur …
Notably, the vast majority of studies were restricted to a single infertility clinic and exclusively relied on nonpublic data sets. C …
Molecular insights into Sertoli cell function: how do metabolic disorders in childhood and adolescence affect spermatogonial fate?
Cannarella R, Curto R, Condorelli RA, Lundy SD, La Vignera S, Calogero AE. Cannarella R, et al. Nat Commun. 2024 Jul 3;15(1):5582. doi: 10.1038/s41467-024-49765-1. Nat Commun. 2024. PMID: 38961093 Free PMC article. Review.
Male infertility is a major public health concern globally with unknown etiology in approximately half of cases. ...
Male infertility is a major public health concern globally with unknown etiology in approximately half of cases. ...
Intersectional analysis of the experiences of women who fail to conceive in low and middle income neighbourhoods of Delhi, India: Findings from a qualitative study.
Adhikary P, Mburu G, Kabra R, Habib NA, Kiarie J, Dhabhai N, Chowdhury R, Mazumder S. Adhikary P, et al. PLoS One. 2024 Jul 3;19(7):e0304029. doi: 10.1371/journal.pone.0304029. eCollection 2024. PLoS One. 2024. PMID: 38959201 Free PMC article.
BACKGROUND: Experiences of delayed conception and infertility have been reported among women. However, the concept of intersectionality is rarely utilised in studies of infertility, and it is particularly uncommon in research from low- and middle- income countries. …
BACKGROUND: Experiences of delayed conception and infertility have been reported among women. However, the concept of intersectionali …
Derivation and validation of the first web-based nomogram to predict the spontaneous pregnancy after reproductive surgery using machine learning models.
Liu Z, Wang M, He S, Wang X, Liu X, Xie X, Bao H. Liu Z, et al. Front Endocrinol (Lausanne). 2024 Jul 2;15:1378157. doi: 10.3389/fendo.2024.1378157. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 39015183 Free PMC article.
OBJECTIVE: Infertility remains a significant global burden over the years. Reproductive surgery is an effective strategy for infertile women. Early prediction of spontaneous pregnancy after reproductive surgery is of high interest for the patients seeking the …
OBJECTIVE: Infertility remains a significant global burden over the years. Reproductive surgery is an effective strategy for i …
Prestimulation parameters predicting the pregnancy outcomes after IVF-ET in patients with unexplained infertility.
Ozturk AC, Dilbaz B, Ozelci R, Dilbaz S. Ozturk AC, et al. Eur Rev Med Pharmacol Sci. 2024 Jul;28(13):3912-3921. doi: 10.26355/eurrev_202407_36523. Eur Rev Med Pharmacol Sci. 2024. PMID: 39012234 Free article.
OBJECTIVE: Assisted Reproductive Technologies (ART) are considered to be the most effective treatment option for unexplained infertility. ...No statistically significant difference was detected in terms of age, infertility duration, and BMI of the patients wh …
OBJECTIVE: Assisted Reproductive Technologies (ART) are considered to be the most effective treatment option for unexplained infer
Parents' 'fault' must not weigh on their children. Surrogacy as a universal crime in Italy: Is it compatible with bioethical principles?
Medenica S, Marinelli S, Radojevic N, De Paola L, Lopez A, Montanari Vergallo G. Medenica S, et al. Clin Ter. 2024 Jul-Aug;175(4):246-251. doi: 10.7417/CT.2024.5071. Clin Ter. 2024. PMID: 39010809 Free article. Review.
Offering real alternatives to surrogacy in an organic and pragmatic fashion (i.e. expediting adoption procedures, favoring motherhood at a younger age, when infertility issues are less likely to have set in) may be the best way to disincentivize fertility traveling and mak …
Offering real alternatives to surrogacy in an organic and pragmatic fashion (i.e. expediting adoption procedures, favoring motherhood at a y …
A common problem between gynecology, obstetrics, and reproductive medicine: Cesarean section scar defect.
Lin PL, Hou JH, Chen CH. Lin PL, et al. Taiwan J Obstet Gynecol. 2024 Jul;63(4):459-470. doi: 10.1016/j.tjog.2024.03.018. Taiwan J Obstet Gynecol. 2024. PMID: 39004471 Free article. Review.
Additionally, CSD manifests with diverse symptoms, such as abnormal uterine bleeding, dysmenorrhea, chronic pelvic pain, dyspareunia, secondary infertility, and Cesarean scar pregnancy. Some symptoms are often attributed to other diagnoses, leading to delayed treatment. .. …
Additionally, CSD manifests with diverse symptoms, such as abnormal uterine bleeding, dysmenorrhea, chronic pelvic pain, dyspareunia, second …
Risks of Placental Abruption and Preterm Delivery in Patients Undergoing Assisted Reproduction.
Zhang JT, Lee R, Sauer MV, Ananth CV. Zhang JT, et al. JAMA Netw Open. 2024 Jul 1;7(7):e2420970. doi: 10.1001/jamanetworkopen.2024.20970. JAMA Netw Open. 2024. PMID: 38985469 Free PMC article.
IMPORTANCE: Patients using assisted reproductive technology (ART) may need additional counseling about the increased risks of placental abruption and preterm delivery. ...These findings have implications for counseling patients who seek infertility treatment and obs …
IMPORTANCE: Patients using assisted reproductive technology (ART) may need additional counseling about the increased risks of placent …
Alkylating agents-induced gonadotoxicity in prepubertal males: Insights on the clinical and preclinical front.
Sriram S, Macedo T, Mavinkurve-Groothuis A, van de Wetering M, Looijenga LHJ. Sriram S, et al. Clin Transl Sci. 2024 Jul;17(7):e13866. doi: 10.1111/cts.13866. Clin Transl Sci. 2024. PMID: 38965809 Free PMC article. Review.
Chemotherapeutic agents can be gonadotoxic, rendering them at risk for infertility post-survival. While semen cryopreservation is an option that can be provided for most (post)pubertal boys before treatment, this is unfortunately not an option prepubertal in age, simply du …
Chemotherapeutic agents can be gonadotoxic, rendering them at risk for infertility post-survival. While semen cryopreservation is an …
Naturally sterile Mus spretus hybrids are suitable for the generation of pseudopregnant embryo transfer recipients.
Preece C, Biggs D, Grencis E, Jackson MS, Allen S, Fray M, Adamson A, Davies B. Preece C, et al. Lab Anim (NY). 2024 Jul;53(7):181-185. doi: 10.1038/s41684-024-01393-4. Epub 2024 Jun 17. Lab Anim (NY). 2024. PMID: 38886565 Free PMC article.
The method provides two substantial 3R impacts: refinement (when compared with surgical vasectomy) and reduction in breeding procedures (compared with sterile transgenic lines). Despite initial promise, the 3Rs impact of this innovation was limited by difficulties in breed …
The method provides two substantial 3R impacts: refinement (when compared with surgical vasectomy) and reduction in breeding procedures (com …
Reduced human fecundity attributable to ambient fine particles in low- and middle-income countries.
Tong M, Lu H, Xu H, Fan X, Zhang JJ, Kelly FJ, Gong J, Han Y, Li P, Wang R, Li J, Zhu T, Xue T. Tong M, et al. Environ Int. 2024 Jul;189:108784. doi: 10.1016/j.envint.2024.108784. Epub 2024 May 31. Environ Int. 2024. PMID: 38852259 Free article.
However, the attributable burden has not been estimated for low- and middle-income countries (LMICs), where the exposure-response function between PM(2.5) and the infertility rate has been insufficiently studied. OBJECTIVE: This study examined the associations between long …
However, the attributable burden has not been estimated for low- and middle-income countries (LMICs), where the exposure-response function b …
Comprehensive analysis of differentially expressed mRNAs, circRNAs, and miRNAs and their ceRNA network in the testis of cattle-yak, yak, and cattle.
Cao M, Xiong L, Wang X, Guo S, Hu L, Kang Y, Wu X, Bao P, Chu M, Liang C, Pei J, Guo X. Cao M, et al. Genomics. 2024 Jul;116(4):110872. doi: 10.1016/j.ygeno.2024.110872. Epub 2024 Jun 6. Genomics. 2024. PMID: 38849017 Free article.
Cattle-yak is a hybrid offspring resulting from the crossbreeding of yak and cattle, and it exhibits substantial heterosis in production performance. However, male sterility in cattle-yak remains a concern. Reports suggest that noncoding RNAs are involved in the regulation …
Cattle-yak is a hybrid offspring resulting from the crossbreeding of yak and cattle, and it exhibits substantial heterosis in production per …
Reproductive toxicity and related mechanisms of micro(nano)plastics in terrestrial mammals: Review of current evidence.
Peng Y, He Q. Peng Y, et al. Ecotoxicol Environ Saf. 2024 Jul 1;279:116505. doi: 10.1016/j.ecoenv.2024.116505. Epub 2024 May 28. Ecotoxicol Environ Saf. 2024. PMID: 38810287 Free article. Review.
Micro(nano)plastics (MNPs) have been detected in various ecological environments and are widely used due to their stable properties, raising widespread concern about their potential human reproductive toxicity. Currently, infertility affects approximately 10-30% of …
Micro(nano)plastics (MNPs) have been detected in various ecological environments and are widely used due to their stable properties, raising …
The gut microbiota contributes to methamphetamine-induced reproductive toxicity in male mice.
Liu JL, Chen LJ, Liu Y, Li JH, Zhang KK, Hsu C, Li XW, Yang JZ, Chen L, Zeng JH, Xie XL, Wang Q. Liu JL, et al. Ecotoxicol Environ Saf. 2024 Jul 1;279:116457. doi: 10.1016/j.ecoenv.2024.116457. Epub 2024 May 15. Ecotoxicol Environ Saf. 2024. PMID: 38754198 Free article.
Testicular RNA sequencing revealed enrichment of several Gene Ontology terms associated with reproductive processes, as well as PI3K-Akt signaling pathways. FMT conveyed similar reproductive damage from METH-treated mice to healthy recipient mice. The aforementioned …
Testicular RNA sequencing revealed enrichment of several Gene Ontology terms associated with reproductive processes, as well as PI3K- …
A Gravid Situation: General Surgery Faculty Support for Pregnant Surgical Residents.
Freudenberger DC, Riner AN, Herremans KM, Vudatha V, McGuire KP, Anand RJ, Trevino JG. Freudenberger DC, et al. J Surg Res. 2024 Jul;299:9-16. doi: 10.1016/j.jss.2024.03.002. Epub 2024 Apr 26. J Surg Res. 2024. PMID: 38677003 Free article.
Given recent reports, 80.2% of surgeons recognized that female surgeons have increased risks of infertility and pregnancy complications. Recurring themes of normalizing pregnancy, improving policies, and creating a culture change were expressed. ...
Given recent reports, 80.2% of surgeons recognized that female surgeons have increased risks of infertility and pregnancy complicatio …
Vitamin D3 among neonates born after in vitro fertilization compared with neonates from the general population.
Walker KC, Pristed SG, Thorsteinsdottir F, Specht IO, Cohen A, Heitmann BL, Kesmodel US. Walker KC, et al. Acta Obstet Gynecol Scand. 2024 Jul;103(7):1329-1338. doi: 10.1111/aogs.14819. Epub 2024 Apr 18. Acta Obstet Gynecol Scand. 2024. PMID: 38637997 Free PMC article.
INTRODUCTION: Sufficient levels of vitamin D have been associated with higher chances for both clinical pregnancy and live birth among women undergoing assisted reproductive techniques, whereas low levels of maternal vitamin D have been associated with preeclampsia and lat …
INTRODUCTION: Sufficient levels of vitamin D have been associated with higher chances for both clinical pregnancy and live birth among women …
Impact of surgery for endometriosis on the outcomes of in vitro fertilization.
Ferrero S, Gazzo I, Crosa M, Rosato FP, Barra F, Leone Roberti Maggiore U. Ferrero S, et al. Best Pract Res Clin Obstet Gynaecol. 2024 Jul;95:102496. doi: 10.1016/j.bpobgyn.2024.102496. Epub 2024 Apr 9. Best Pract Res Clin Obstet Gynaecol. 2024. PMID: 38631927 Free article. Review.
Comparative efficacy of exercise, diet and/or pharmacological interventions on BMI, ovulation, and hormonal profile in reproductive-aged women with overweight or obesity: a systematic review and network meta-analysis.
Ruiz-González D, Cavero-Redondo I, Hernández-Martínez A, Baena-Raya A, Martínez-Forte S, Altmäe S, Fernández-Alonso AM, Soriano-Maldonado A. Ruiz-González D, et al. Hum Reprod Update. 2024 Jul 1;30(4):472-487. doi: 10.1093/humupd/dmae008. Hum Reprod Update. 2024. PMID: 38627233 Free PMC article.
BACKGROUND: The increasing prevalence of obesity worldwide poses a significant threat to reproductive function owing, in part, to hormonal disturbances caused by negative feedback between excess adiposity and the hypothalamic-pituitary-ovarian axis. ...The primary outcomes …
BACKGROUND: The increasing prevalence of obesity worldwide poses a significant threat to reproductive function owing, in part, to hor …
The endometrial transcriptome of infertile women with and without implantation failure.
Bui BN, Kukushkina V, Meltsov A, Olsen C, van Hoogenhuijze N, Altmäe S, Mol F, Teklenburg G, de Bruin JP, Besselink D, Stevens Brentjens L, Obukhova D, Zamani Esteki M, van Golde R, Romano A, Laisk T, Steba G, Mackens S, Salumets A, Broekmans F. Bui BN, et al. Acta Obstet Gynecol Scand. 2024 Jul;103(7):1348-1365. doi: 10.1111/aogs.14822. Epub 2024 Mar 22. Acta Obstet Gynecol Scand. 2024. PMID: 38520066 Free PMC article.
Analyzing the endometrial transcriptome analysis may reveal the underlying processes and could help in guiding prognosis and using targeted interventions for infertility. This exploratory study investigated whether the endometrial transcriptome profile was associated with …
Analyzing the endometrial transcriptome analysis may reveal the underlying processes and could help in guiding prognosis and using targeted …
Navigating fertility dilemmas across the lifespan in girls with Turner syndrome-a scoping review.
van der Coelen S, van der Velden J, Nadesapillai S, Braat D, Peek R, Fleischer K. van der Coelen S, et al. Hum Reprod Update. 2024 Jul 1;30(4):383-409. doi: 10.1093/humupd/dmae005. Hum Reprod Update. 2024. PMID: 38452347 Free PMC article. Review.
SEARCH METHODS: Databases of PubMed, Embase, and Web of science were searched using the following key terms: Turner syndrome, fertility, puberty, pregnancy, sex-hormones, karyotype, fertility preservation, assisted reproductive techniques, and counselling, alongside releva …
SEARCH METHODS: Databases of PubMed, Embase, and Web of science were searched using the following key terms: Turner syndrome, fertility, pub …
Novel PLCZ1 mutation caused polyspermy during in vitro fertilization.
Tong KY, Liu WW, Sun LW, Liu DY, Xiang YZ, Li C, Chai LW, Chen K, Huang GN, Li JY. Tong KY, et al. Asian J Androl. 2024 Jul 1;26(4):389-395. doi: 10.4103/aja202376. Epub 2024 Mar 5. Asian J Androl. 2024. PMID: 38445955 Free article.
Whole-exome sequencing (WES) was performed to identify candidate mutations in couples with primary infertility. Sanger sequencing was used to validate the mutations. Multiple PLCZ1 -mutated sperm were injected into human and mouse oocytes to explore whether PN formation wa …
Whole-exome sequencing (WES) was performed to identify candidate mutations in couples with primary infertility. Sanger sequencing was …
Prediction of pregnancy-related complications in women undergoing assisted reproduction, using machine learning methods.
Wang C, Johansson ALV, Nyberg C, Pareek A, Almqvist C, Hernandez-Diaz S, Oberg AS. Wang C, et al. Fertil Steril. 2024 Jul;122(1):95-105. doi: 10.1016/j.fertnstert.2024.02.024. Epub 2024 Feb 17. Fertil Steril. 2024. PMID: 38373676 Free article.
OBJECTIVE: To use machine learning methods to develop prediction models of pregnancy complications in women who conceived with assisted reproductive techniques (ART). DESIGN: A nation-wide register-based cohort study with prospectively collected data. ...The top influentia …
OBJECTIVE: To use machine learning methods to develop prediction models of pregnancy complications in women who conceived with assisted r
Intravaginal exposure to seminal plasma after ovum pick-up does not increase live birth rates after in vitro fertilization or intracytoplasmic sperm injection treatment: a double-blind, placebo-controlled randomized trial.
Liffner S, Bladh M, Rodriguez-Martinez H, Sydsjö G, Zalavary S, Nedstrand E. Liffner S, et al. Fertil Steril. 2024 Jul;122(1):131-139. doi: 10.1016/j.fertnstert.2024.02.002. Epub 2024 Feb 9. Fertil Steril. 2024. PMID: 38342372 Free article. Clinical Trial.
Follicle stimulating hormone controls granulosa cell glutamine synthesis to regulate ovulation.
Zhang KH, Zhang FF, Zhang ZL, Fang KF, Sun WX, Kong N, Wu M, Liu HO, Liu Y, Li Z, Cai QQ, Wang Y, Wei QW, Lin PC, Lin Y, Xu W, Xu CJ, Yuan YY, Zhao SM. Zhang KH, et al. Protein Cell. 2024 Jul 1;15(7):512-529. doi: 10.1093/procel/pwad065. Protein Cell. 2024. PMID: 38167949 Free PMC article.
Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility. Inadequate understanding of the ovulation drivers hinders PCOS intervention. ...
Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility. Inadequate understanding of the ovulation drivers h …
Nutritional and exercise interventions to improve conception in women suffering from obesity and distinct nosological entities.
Gitsi E, Livadas S, Argyrakopoulou G. Gitsi E, et al. Front Endocrinol (Lausanne). 2024 Jun 28;15:1426542. doi: 10.3389/fendo.2024.1426542. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 39006367 Free PMC article. Review.
Infertility among women, particularly those living with obesity, presents a multifaceted challenge with implications for reproductive health worldwide. ...By synthesizing existing findings and recommendations, this review contributes to the understanding of lifestyl
Infertility among women, particularly those living with obesity, presents a multifaceted challenge with implications for reproduct
The Role of Tubulin Polymerization-Promoting Protein2 (TPPP2) in Spermatogenesis: A Narrative Review.
Orosz F. Orosz F. Int J Mol Sci. 2024 Jun 27;25(13):7017. doi: 10.3390/ijms25137017. Int J Mol Sci. 2024. PMID: 39000129 Free PMC article. Review.
Its possible role in spermatogenesis is described in this narrative review. TPPP2 is expressed specifically in the male reproductive system, mainly in testes and sperm, and also in the epididymis. ...
Its possible role in spermatogenesis is described in this narrative review. TPPP2 is expressed specifically in the male reproductive
Assessing the Risks of Pesticide Exposure: Implications for Endocrine Disruption and Male Fertility.
Uwamahoro C, Jo JH, Jang SI, Jung EJ, Lee WJ, Bae JW, Kwon WS. Uwamahoro C, et al. Int J Mol Sci. 2024 Jun 25;25(13):6945. doi: 10.3390/ijms25136945. Int J Mol Sci. 2024. PMID: 39000054 Free PMC article. Review.
Pesticides disrupt the endocrine system, leading to neurological impairments, hepatocellular abnormalities, cardiac dysfunction, and respiratory issues. Furthermore, they also exert adverse effects on reproductive organs, disrupting hormone levels and causing reproducti
Pesticides disrupt the endocrine system, leading to neurological impairments, hepatocellular abnormalities, cardiac dysfunction, and respira …
The Role of Retinoic Acid in Spermatogenesis and Its Application in Male Reproduction.
Zhao Y, Deng S, Li C, Cao J, Wu A, Chen M, Ma X, Wu S, Lian Z. Zhao Y, et al. Cells. 2024 Jun 24;13(13):1092. doi: 10.3390/cells13131092. Cells. 2024. PMID: 38994945 Free PMC article. Review.
Although retinoic acid can restore fertility in some males with reproductive disorders, it does not work universally. Furthermore, high doses may adversely affect reproduction. ...In addition to the treatment of male reproductive disorders, the role of retinoic acid …
Although retinoic acid can restore fertility in some males with reproductive disorders, it does not work universally. Furthermore, hi …
Reproductive function and behaviors: an update on the role of neural estrogen receptors alpha and beta.
Torres T, Adam N, Mhaouty-Kodja S, Naulé L. Torres T, et al. Front Endocrinol (Lausanne). 2024 Jun 24;15:1408677. doi: 10.3389/fendo.2024.1408677. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38978624 Free PMC article. Review.
Infertility is becoming a major public health problem, with increasing frequency due to medical, environmental and societal causes. ...Fertility relies on fine-tuned control of both neuroendocrine function and reproductive behaviors, those are critically regulated b
Infertility is becoming a major public health problem, with increasing frequency due to medical, environmental and societal causes. .
Protein disulfide isomerase is essential for spermatogenesis in mice.
Zhang Y, Yang A, Zhao Z, Chen F, Yan X, Han Y, Wu D, Wu Y. Zhang Y, et al. JCI Insight. 2024 Jun 24;9(12):e177743. doi: 10.1172/jci.insight.177743. JCI Insight. 2024. PMID: 38912589 Free article.
Both inducible whole-body PDI-KO (UBC-Cre/Pdifl/fl) mice and premeiotic PDI-KO (Stra8-Cre/Pdifl/fl) mice experienced a significant decrease in germ cells, testicular atrophy, oligospermia, and complete male infertility. Stra8-Cre/Pdifl/fl spermatocytes had significantly up …
Both inducible whole-body PDI-KO (UBC-Cre/Pdifl/fl) mice and premeiotic PDI-KO (Stra8-Cre/Pdifl/fl) mice experienced a significant decrease …
The Molecular Link between Obesity and the Endometrial Environment: A Starting Point for Female Infertility.
Gonnella F, Konstantinidou F, Donato M, Gatta DMP, Peserico A, Barboni B, Stuppia L, Nothnick WB, Gatta V. Gonnella F, et al. Int J Mol Sci. 2024 Jun 22;25(13):6855. doi: 10.3390/ijms25136855. Int J Mol Sci. 2024. PMID: 38999965 Free PMC article. Review.
Female infertility constitutes a growing health problem in developing countries and could be associated with several possible causes including reproductive disorders, congenital malformations, infections and hormonal dysfunction. ...Excess weight is associated with …
Female infertility constitutes a growing health problem in developing countries and could be associated with several possible causes …
TENT5-mediated polyadenylation of mRNAs encoding secreted proteins is essential for gametogenesis in mice.
Brouze M, Czarnocka-Cieciura A, Gewartowska O, Kusio-Kobiałka M, Jachacy K, Szpila M, Tarkowski B, Gruchota J, Krawczyk P, Mroczek S, Borsuk E, Dziembowski A. Brouze M, et al. Nat Commun. 2024 Jun 22;15(1):5331. doi: 10.1038/s41467-024-49479-4. Nat Commun. 2024. PMID: 38909026 Free PMC article.
Additionally, TENT5B-GFP knock-in females display a gain-of-function infertility effect, with multiple chromosomal aberrations in ovulated oocytes. TENT5C and TENT5D both regulate different stages of spermatogenesis, as shown by the sterility in males following the …
Additionally, TENT5B-GFP knock-in females display a gain-of-function infertility effect, with multiple chromosomal aberrations in ovu …
Combined analysis of estradiol and β-hCG to predict the early pregnancy outcome of FET: a retrospective study.
Wu M, Xiao X, Wang C, Zhao M, Xiong F, Jin X, Zheng X. Wu M, et al. J Ovarian Res. 2024 Jun 21;17(1):128. doi: 10.1186/s13048-024-01433-0. J Ovarian Res. 2024. PMID: 38907300 Free PMC article.
The objective of this study was to investigate the predictive efficacy of combining serum E(2) and beta-hCG levels on early reproductive outcomes 12 days after embryo transfer. METHODS: A total of 1521 patients with beta-hCG positive values on day 12 following frozen-thawe …
The objective of this study was to investigate the predictive efficacy of combining serum E(2) and beta-hCG levels on early reproductive
Iodine and other factors associated with fertility outcome following oil-soluble contrast medium hysterosalpingography: a prospective cohort study.
Mathews DM, Peart JM, Sim RG, Johnson NP, O'Sullivan S, Derraik JGB, Hofman PL. Mathews DM, et al. Front Endocrinol (Lausanne). 2024 Jun 20;15:1257888. doi: 10.3389/fendo.2024.1257888. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38974579 Free PMC article.
SETTING: Auckland, New Zealand (2019-2021). SAMPLE: 196 women with primary or secondary infertility who underwent OSCM HSG. METHODS: Baseline and serial urine iodine concentrations (UIC) and thyroid function tests were measured over six months following the HSG. ...
SETTING: Auckland, New Zealand (2019-2021). SAMPLE: 196 women with primary or secondary infertility who underwent OSCM HSG. METHODS: …
The Odad3 Gene Is Necessary for Spermatozoa Development and Male Fertility in Mice.
Pasquini M, Chiani F, Gambadoro A, Di Pietro C, Paoletti R, Orsini T, Putti S, Scavizzi F, La Sala G, Ermakova O. Pasquini M, et al. Cells. 2024 Jun 18;13(12):1053. doi: 10.3390/cells13121053. Cells. 2024. PMID: 38920681 Free PMC article.
Previously, we demonstrated that knockout of the Odad3 gene in mice replicates several features of PCD, such as hydrocephalus, defects in left-right body symmetry, and male infertility, with a complete absence of sperm in the reproductive tract. ...
Previously, we demonstrated that knockout of the Odad3 gene in mice replicates several features of PCD, such as hydrocephalus, defects in le …
Genome-Wide CRISPR Screen Identifies an NF2-Adherens Junction Mechanistic Dependency for Cardiac Lineage.
Lee CJM, Autio MI, Zheng W, Song Y, Wang SC, Wong DCP, Xiao J, Zhu Y, Yusoff P, Yei X, Chock WK, Low BC, Sudol M, Foo RS. Lee CJM, et al. Circulation. 2024 Jun 18;149(25):1960-1979. doi: 10.1161/CIRCULATIONAHA.122.061335. Epub 2024 May 16. Circulation. 2024. PMID: 38752370 Free article.
Furthermore, we found that NF2 and AMOT (angiomotin) cooperatively bind to YAP (yes-associated protein) during mesendoderm formation, thereby preventing YAP activation, independent of canonical MST (mammalian sterile 20-like serine-threonine protein kinase)-LATS (large tum …
Furthermore, we found that NF2 and AMOT (angiomotin) cooperatively bind to YAP (yes-associated protein) during mesendoderm formation, thereb …
DNA methylation patterns in patients with asthenospermia and oligoasthenospermia.
Zhang J, Li X, Wang R, Feng X, Wang S, Wang H, Wang Y, Li H, Li Y, Guo Y. Zhang J, et al. BMC Genomics. 2024 Jun 17;25(1):602. doi: 10.1186/s12864-024-10491-z. BMC Genomics. 2024. PMID: 38886667 Free PMC article.
Of note, 12, 9, and 8 DMRs in each group were closely associated with spermatogenesis and male infertility. Furthermore, BDNF, SMARCB1, PIK3CA, and DDX27; RBMX and SPATA17; ASZ1, CDH1, and CHDH were identified as strong differentially methylated candidate genes in each gro …
Of note, 12, 9, and 8 DMRs in each group were closely associated with spermatogenesis and male infertility. Furthermore, BDNF, SMARCB …
Assisted reproductive technology (ART) patient information-seeking behavior: a qualitative study.
Mayette E, Scalise A, Li A, McGeorge N, James K, Mahalingaiah S. Mayette E, et al. BMC Womens Health. 2024 Jun 15;24(1):346. doi: 10.1186/s12905-024-03183-z. BMC Womens Health. 2024. PMID: 38877503 Free PMC article.
BACKGROUND: Approximately 13% of women in the United States of reproductive age seek infertility services. Assisted reproductive technology (ART), including in vitro fertilization, is used to help patients achieve pregnancy. ...
BACKGROUND: Approximately 13% of women in the United States of reproductive age seek infertility services. Assisted reprodu
Phthalate exposure and subfecundity in preconception couples: A nested case-control study.
Yin A, Mao L, Zhang C, Du B, Xiong X, Chen A, Cheng L, Zhang Z, Li X, Zhou Y, Jiang H. Yin A, et al. Ecotoxicol Environ Saf. 2024 Jun 15;278:116428. doi: 10.1016/j.ecoenv.2024.116428. Epub 2024 May 8. Ecotoxicol Environ Saf. 2024. PMID: 38723384 Free article.
Our research reinforced the need of monitoring PAE exposure for the purpose of improving human reproductive health....
Our research reinforced the need of monitoring PAE exposure for the purpose of improving human reproductive health....
The type of COVID-19 vaccination does not affect reproductive function and pregnancy outcomes in infertile couples.
Wang S, Wang N, Yao G, Su Y, Qi L. Wang S, et al. Front Endocrinol (Lausanne). 2024 Jun 14;15:1356938. doi: 10.3389/fendo.2024.1356938. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38948529 Free PMC article.
To complement and confirm the existing findings, this research aimed to investigate whether there are adverse effects of different vaccine types in females and males on reproductive function and clinical pregnancy. METHODS: This retrospective study enrolled 6,455 fresh emb …
To complement and confirm the existing findings, this research aimed to investigate whether there are adverse effects of different vaccine t …
Impaired embryo development potential associated with thyroid autoimmunity in euthyroid infertile women with diminished ovarian reserve.
Zhang Y, Zhang Y, Su Z, Ren B, Yu S, Li W, Xu N, Lou H. Zhang Y, et al. Front Endocrinol (Lausanne). 2024 Jun 14;15:1376179. doi: 10.3389/fendo.2024.1376179. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38948519 Free PMC article.
PURPOSE: The aim of this study was to evaluate the associations of thyroid autoimmunity (TAI) with the number of oocytes retrieved (NOR), fertilization rate (FR), and embryo quality (EQ) in euthyroid women with infertility and diminished ovarian reserve (DOR). METHODS: Thi …
PURPOSE: The aim of this study was to evaluate the associations of thyroid autoimmunity (TAI) with the number of oocytes retrieved (NOR), fe …
Fertility issues in women of childbearing age with spondyloarthritis.
Bindoli S, Cozzi G, Lorenzin M, Sfriso P, Doria A, Scagnellato L, Ramonda R. Bindoli S, et al. Front Immunol. 2024 Jun 14;15:1412174. doi: 10.3389/fimmu.2024.1412174. eCollection 2024. Front Immunol. 2024. PMID: 38947314 Free PMC article. Review.
In all women of childbearing age with rheumatic diseases, preconception counselling is paramount, and a referral to a reproductive specialist should be considered in the presence of multiple factors that may influence fertility. ...
In all women of childbearing age with rheumatic diseases, preconception counselling is paramount, and a referral to a reproductive sp …
Treating refractory thin endometrium through a novel way of activation and administration of Platelet-rich plasma in sexually active women: An interventional prospective cohort clinical study.
Abbassi R, Haddad S, Haneyah F, Nakawa W, Murad MS, Issa AM, Alkheder A, Azar A, Dakhalalah Bani Hani M, Abbassi H. Abbassi R, et al. Medicine (Baltimore). 2024 Jun 14;103(24):e38554. doi: 10.1097/MD.0000000000038554. Medicine (Baltimore). 2024. PMID: 38875415 Free PMC article.
Further research is needed to confirm these findings in larger and more diverse populations, along with exploring long-term reproductive success rates post-PRP treatment....
Further research is needed to confirm these findings in larger and more diverse populations, along with exploring long-term reproductive
History of the Development of Knowledge about the Neuroendocrine Control of Ovulation-Recent Knowledge on the Molecular Background.
Szabó F, Köves K, Gál L. Szabó F, et al. Int J Mol Sci. 2024 Jun 13;25(12):6531. doi: 10.3390/ijms25126531. Int J Mol Sci. 2024. PMID: 38928237 Free PMC article. Review.
The discovery of releasing and inhibiting hormones, the significance of pulse and surge generators, the pulsatile secretion of the gonadotropin-releasing hormone (GnRH), and the subsequent pulsatility of luteinizing (LH) and follicle-stimulating hormones (FSH) in the human rep
The discovery of releasing and inhibiting hormones, the significance of pulse and surge generators, the pulsatile secretion of the gonadotro …
Paternal Inheritance of Mitochondrial DNA May Lead to Dioecy in Conifers.
de Jong TJ, Shmida A. de Jong TJ, et al. Acta Biotheor. 2024 Jun 13;72(2):7. doi: 10.1007/s10441-024-09481-1. Acta Biotheor. 2024. PMID: 38869631 Free PMC article.
In angiosperms cytoplasmic DNA is typically passed on maternally through ovules. Genes in the mtDNA may cause male sterility. When male-sterile (female) cytotypes produce more seeds than cosexuals, they pass on more copies of their mtDNA and will co-occur with cosex …
In angiosperms cytoplasmic DNA is typically passed on maternally through ovules. Genes in the mtDNA may cause male sterility. When ma …
Investigating the potential of X chromosome shredding for mouse genetic biocontrol.
Bunting MD, Godahewa GI, McPherson NO, Robertson LJ, Gierus L, Piltz SG, Edwards O, Tizard M, Thomas PQ. Bunting MD, et al. Sci Rep. 2024 Jun 12;14(1):13466. doi: 10.1038/s41598-024-63706-4. Sci Rep. 2024. PMID: 38866815 Free PMC article.
Instead, cleavage of the X chromosome during meiosis typically resulted in a spermatogenic block, manifest as small testes volume, empty tubules, low sperm concentration, and sub/infertility. Our study highlights the importance of controlling the timing of CRISPR-Cas9 acti …
Instead, cleavage of the X chromosome during meiosis typically resulted in a spermatogenic block, manifest as small testes volume, empty tub …
Shear wave elastography to assess stiffness of the human ovary and other reproductive tissues across the reproductive lifespan in health and disease.
Zaniker EJ, Zhang M, Hughes L, La Follette L, Atazhanova T, Trofimchuk A, Babayev E, Duncan FE. Zaniker EJ, et al. Biol Reprod. 2024 Jun 12;110(6):1100-1114. doi: 10.1093/biolre/ioae050. Biol Reprod. 2024. PMID: 38609185 Free PMC article. Review.
In this study, we review the underlying principles of shear wave elastography and its current clinical uses outside the reproductive tract as well as its successful application of shear wave elastography to reproductive tissues, including the uterus and cervix. ...E …
In this study, we review the underlying principles of shear wave elastography and its current clinical uses outside the reproductive
Feasible Influence of G-CSF on Clinical Pregnancy Outcome in Oocyte Donation Cycles for Patients with Recurrent Implantation Failure.
Kushniruk N, Stastna A, Fait T, Lenertova T. Kushniruk N, et al. Medicina (Kaunas). 2024 Jun 11;60(6):966. doi: 10.3390/medicina60060966. Medicina (Kaunas). 2024. PMID: 38929583 Free PMC article.
All women have had a previous history of unsuccessful history of infertility treatment with their own genetic material and at least one ineffective cycle with the donated oocytes. ...
All women have had a previous history of unsuccessful history of infertility treatment with their own genetic material and at least o …
Current research of Assisted Reproductive Technology for women with early endometrial cancer and atypical endometrial hyperplasia after conservative treatment.
Jiang YL, Lin YY, Chen CX, Li YX, Xie HY, Zheng BH. Jiang YL, et al. Front Endocrinol (Lausanne). 2024 Jun 11;15:1377396. doi: 10.3389/fendo.2024.1377396. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38919483 Free PMC article. Review.
Age, obesity, and irregular ovulation are not only high-risk factors for endometrial lesions but also key factors affecting female fertility. Assisted reproductive technology (ART) can significantly improve pregnancy outcomes in patients with AEH and EC after conservative …
Age, obesity, and irregular ovulation are not only high-risk factors for endometrial lesions but also key factors affecting female fertility …
Octanoic acid mitigates busulfan-induced blood-testis barrier damage by alleviating oxidative stress and autophagy.
Cao C, Zhang H, He Z, Zhang K, Qian Z, Shen J, Zheng L, Xue M, Sun S, Li C, Zhao W, Jing J, Ma R, Ge X, Yao B. Cao C, et al. Lipids Health Dis. 2024 Jun 11;23(1):180. doi: 10.1186/s12944-024-02157-2. Lipids Health Dis. 2024. PMID: 38862993 Free PMC article.
BACKGROUND: The management of male infertility continues to encounter an array of challenges and constraints, necessitating an in-depth exploration of novel therapeutic targets to enhance its efficacy. ...These findings provide a deeper understanding of the toxicology of b …
BACKGROUND: The management of male infertility continues to encounter an array of challenges and constraints, necessitating an in-dep …
Investigating possibilities for surveillance of long term chlamydia complications in the Netherlands: A qualitative study.
den Boogert EM, van Aar F, Heijne JCM. den Boogert EM, et al. PLoS One. 2024 Jun 11;19(6):e0305279. doi: 10.1371/journal.pone.0305279. eCollection 2024. PLoS One. 2024. PMID: 38861585 Free PMC article.
Chlamydia can cause long term complications such as pelvic inflammatory disease (PID), ectopic pregnancy (EP) and tubal factor infertility (TFI). Changing testing strategies, for example reduced asymptomatic testing, influence chlamydia surveillance, highlighting the need …
Chlamydia can cause long term complications such as pelvic inflammatory disease (PID), ectopic pregnancy (EP) and tubal factor infertilit
Floral Morphometry and Sexual System Determination in Pink Pepper (Schinus terebinthifolia - Anacardiaceae).
Santos RS, Santos PCS, Carvalho Junior CRN, Leite JA, Silva MAD, Pereira HN, Gallo R. Santos RS, et al. Braz J Biol. 2024 Jun 10;84:e278836. doi: 10.1590/1519-6984.278836. eCollection 2024. Braz J Biol. 2024. PMID: 38865565 Free article.
The increasing global importance of pink peppertree (Schinus terebinthifolia, Anacardiaceae) as a high-value commercial crop and its potential for expansion in production demand appropriate management due to uncertainties regarding its sexual system. This study focused on evaluat …
The increasing global importance of pink peppertree (Schinus terebinthifolia, Anacardiaceae) as a high-value commercial crop and its potenti …
Male Genetic Evaluation in Infertility, Recurrent Abortion and Recurrent in Vitro Fertilization Failure; A Clinical Approach.
Akhavizadegan H. Akhavizadegan H. Urol J. 2024 Jun 9;21(4):221-225. doi: 10.22037/uj.v20i.8044. Urol J. 2024. PMID: 38264866 Free article. Review.
PURPOSE: This review presents a clinical approach to genetic issues in male infertility. Unlike other related reviews that discuss different types of genetic diseases (such as Klinefelter and Down syndrome), this review focuses on the clinical features that result from the …
PURPOSE: This review presents a clinical approach to genetic issues in male infertility. Unlike other related reviews that discuss di …
Bariatric surgery for spontaneous ovulation in women living with polycystic ovary syndrome: the BAMBINI multicentre, open-label, randomised controlled trial.
Samarasinghe SNS, Leca B, Alabdulkader S, Dimitriadis GK, Davasgaium A, Thadani P, Parry K, Luli M, O'Donnell K, Johnson B, Abbara A, Seyfried F, Morman R, Ahmed AR, Hakky S, Tsironis C, Purkayastha S, le Roux CW, Franks S, Menon V, Randeva H, Miras AD. Samarasinghe SNS, et al. Lancet. 2024 Jun 8;403(10443):2489-2503. doi: 10.1016/S0140-6736(24)00538-5. Epub 2024 May 20. Lancet. 2024. PMID: 38782004 Free article. Clinical Trial.
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. Obesity exacerbates the reproductive complications of PCOS; however, the management of obesity in women with PCOS remains a large unmet clinical need. ...
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. Obesity exacerbates the reproduc
Predicting personalized cumulative live birth rate after a complete in vitro fertilization cycle: an analysis of 32,306 treatment cycles in China.
Xia L, Han S, Huang J, Zhao Y, Tian L, Zhang S, Cai L, Xia L, Liu H, Wu Q. Xia L, et al. Reprod Biol Endocrinol. 2024 Jun 7;22(1):65. doi: 10.1186/s12958-024-01237-3. Reprod Biol Endocrinol. 2024. PMID: 38849798 Free PMC article.
RESULTS: Predictors of pre-treatment model included female age (non-linear relationship), antral follicle count (non-linear relationship), body mass index, number of previous IVF attempts, number of previous embryo transfer failure, type of infertility, tubal factor, male …
RESULTS: Predictors of pre-treatment model included female age (non-linear relationship), antral follicle count (non-linear relationship), b …
Examining the causal relationship between sex hormone-binding globulin (SHBG) and infertility: A Mendelian randomization study.
Ma H, Chen Y. Ma H, et al. PLoS One. 2024 Jun 7;19(6):e0304216. doi: 10.1371/journal.pone.0304216. eCollection 2024. PLoS One. 2024. PMID: 38848344 Free PMC article.
RESULTS: Our findings revealed a significant negative association between sex hormone-binding globulin (SHBG) levels and infertility, particularly with anovulation, a specific form of female infertility. However, SHBG did not exert a causal impact on male inferti
RESULTS: Our findings revealed a significant negative association between sex hormone-binding globulin (SHBG) levels and infertility, …
Immunomodulatory Treatment Impact on IVF Outcomes in KIR AA Genotype: Personalized Fertility Insights.
Seles L, Zaha IA, Luncan M, Bodog A, Sachelarie L, Sandor M, Macovei IC, Bimbo-Szuhai E, Huniadi A. Seles L, et al. Medicina (Kaunas). 2024 Jun 6;60(6):948. doi: 10.3390/medicina60060948. Medicina (Kaunas). 2024. PMID: 38929565 Free PMC article.
Couples were divided into two groups: KIR AA (Group A) and KIR Bx (Group B). Results: Factors such as age, type of infertility, oocytes retrieved, embryos produced, pregnancy rates in Group A without and with immunomodulatory treatment were documented. ...
Couples were divided into two groups: KIR AA (Group A) and KIR Bx (Group B). Results: Factors such as age, type of infertility, oocyt …
Genome-wide DNA methylation changes in human spermatogenesis.
Siebert-Kuss LM, Dietrich V, Di Persio S, Bhaskaran J, Stehling M, Cremers JF, Sandmann S, Varghese J, Kliesch S, Schlatt S, Vaquerizas JM, Neuhaus N, Laurentino S. Siebert-Kuss LM, et al. Am J Hum Genet. 2024 Jun 6;111(6):1125-1139. doi: 10.1016/j.ajhg.2024.04.017. Epub 2024 May 16. Am J Hum Genet. 2024. PMID: 38759652 Free PMC article.
Tuberculosis in pregnancy and assisted reproductive technology.
Cao W, Fu X, Li H, Bei J, Li L, Wang L. Cao W, et al. Drug Discov Ther. 2024 Jun 6;18(2):80-88. doi: 10.5582/ddt.2024.01007. Epub 2024 Apr 17. Drug Discov Ther. 2024. PMID: 38631867 Free article. Review.
In the world, tuberculosis is an important factor affecting women's reproductive health, which can cause reproductive tract anatomy abnormalities, embryo implantation obstacles, ovarian reserve and ovulation dysfunction, leading to female infertility. This gr …
In the world, tuberculosis is an important factor affecting women's reproductive health, which can cause reproductive tract an …
X‑chromosome loss rescues Sertoli cell maturation and spermatogenesis in Klinefelter syndrome.
Winge SB, Skakkebaek NE, Aksglaede L, Saritaş G, Rajpert-De Meyts E, Goossens E, Juul A, Almstrup K. Winge SB, et al. Cell Death Dis. 2024 Jun 5;15(6):396. doi: 10.1038/s41419-024-06792-6. Cell Death Dis. 2024. PMID: 38839795 Free PMC article.
Klinefelter syndrome (47,XXY) causes infertility with a testicular histology comprising two types of Sertoli cell-only tubules, representing mature and immature-like Sertoli cells, and occasionally focal spermatogenesis. ...
Klinefelter syndrome (47,XXY) causes infertility with a testicular histology comprising two types of Sertoli cell-only tubules, repre …
Interplay between male gonadal function and overall male health.
Asero V, Scornajenghi CM, Iaconis S, Sicignano E, Falcone A, Dinacci F, Pagano G, Carino D, Corvino R, Tresh A. Asero V, et al. J Basic Clin Physiol Pharmacol. 2024 Jun 5;35(3):105-110. doi: 10.1515/jbcpp-2024-0054. eCollection 2024 May 1. J Basic Clin Physiol Pharmacol. 2024. PMID: 38830206 Free article. Review.
Numerous conditions with systemic implications have been identified, encompassing genetic factors (such as Klinefelter Syndrome), obesity, psychological stress, environmental factors, and others. Consequently, infertility assessment-presents an opportunity for comprehensiv …
Numerous conditions with systemic implications have been identified, encompassing genetic factors (such as Klinefelter Syndrome), obesity, p …
Trends in acupuncture for infertility: a scoping review with bibliometric and visual analysis.
Tian Z, Zhang C, Liao X, Yang S, Hong Y, Shi A, Yan F, Pan T, Zhang J, Meng Y, Robinson N, Bai P, Gang W. Tian Z, et al. Front Endocrinol (Lausanne). 2024 Jun 4;15:1351281. doi: 10.3389/fendo.2024.1351281. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38894745 Free PMC article. Review.
BACKGROUND: Unexplained recurrent implantation failure and the high cost of assisted reproductive techniques for those experiencing infertility have increasingly resulted in the use of acupuncture. ...Out of the 274 primary studies, there were 40 (14.60%) cases of m …
BACKGROUND: Unexplained recurrent implantation failure and the high cost of assisted reproductive techniques for those experiencing …
Prescribing Patterns for Postpartum Contraception Among Breastfeeding Patients Insured Under Medicaid in Rhode Island: A PRAMS Analysis.
Whelan AR, Amanullah S, Gjelsvik A. Whelan AR, et al. R I Med J (2013). 2024 Jun 3;107(6):24-28. R I Med J (2013). 2024. PMID: 38810012 Free article.
People of color, those of lower socio-economic status, and Medicaid insurance are more likely to receive contraception/sterilization counseling than White patients. Postpartum contraceptive choice is an important aspect for pregnant people, especially for those who plan to …
People of color, those of lower socio-economic status, and Medicaid insurance are more likely to receive contraception/sterilization
The mammalian sperm factor phospholipase C zeta is critical for early embryo division and pregnancy in humans and mice.
Kashir J, Mistry BV, Rajab MA, BuSaleh L, Abu-Dawud R, Ahmed HA, Alharbi S, Nomikos M, AlHassan S, Coskun S, Assiri AM. Kashir J, et al. Hum Reprod. 2024 Jun 3;39(6):1256-1274. doi: 10.1093/humrep/deae078. Hum Reprod. 2024. PMID: 38670547 Free PMC article.
STUDY DESIGN, SIZE, DURATION: A cohort of 54 couples undergoing fertility treatment were recruited at the assisted reproductive technology laboratory at the King Faisal Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia. ...LIMITATIONS, REASONS FOR CAUTION: The …
STUDY DESIGN, SIZE, DURATION: A cohort of 54 couples undergoing fertility treatment were recruited at the assisted reproductive techn …
Hysterosalpingo-foam sonography versus hysterosalpingography during fertility work-up: an economic evaluation alongside a randomized controlled trial.
Kamphuis D, van Eekelen R, van Welie N, Dreyer K, van Rijswijk J, van Hooff MHA, de Bruin JP, Verhoeve HR, Mol F, van Baal WM, Traas MAF, van Peperstraten AM, Manger AP, Gianotten J, de Koning CH, Koning AMH, Bayram N, van der Ham DP, Vrouenraets FPJM, Kalafusova M, van de Laar BIG, Kaijser J, Lambeek AF, Meijer WJ, Broekmans FJM, Valkenburg O, van der Voet LF, van Disseldorp J, Lambers MJ, Tros R, Lambalk CB, Stoker J, van Wely M, Bossuyt PMM, Mol BWJ, Mijatovic V. Kamphuis D, et al. Hum Reprod. 2024 Jun 3;39(6):1222-1230. doi: 10.1093/humrep/deae071. Hum Reprod. 2024. PMID: 38600625 Free PMC article. Clinical Trial.
The Role of Total Oxidant and Antioxidant Levels in Follicular Fluid in Unexplained Infertility.
Topdagi SK, Topdagi YE, Ozdemir I, Borekci B. Topdagi SK, et al. Niger J Clin Pract. 2024 Jun 1;27(6):739-747. doi: 10.4103/njcp.njcp_836_23. Epub 2024 Jun 29. Niger J Clin Pract. 2024. PMID: 38943298 Free article.
BACKGROUND: Unexplained infertility is defined as the absence of any pathology in the basic evaluation performed in couples who cannot achieve pregnancy after 1 year of unprotected sexual intercourse. The results of tests examining the causes of infertility show no …
BACKGROUND: Unexplained infertility is defined as the absence of any pathology in the basic evaluation performed in couples who canno …
Mechanisms of meiosis initiation and meiotic prophase progression during spermatogenesis.
Ishiguro KI. Ishiguro KI. Mol Aspects Med. 2024 Jun;97:101282. doi: 10.1016/j.mam.2024.101282. Epub 2024 May 25. Mol Aspects Med. 2024. PMID: 38797021 Free article. Review.
This review highlights the mechanisms of meiotic initiation and meiotic prophase progression from the point of the gene expression program and its relevance to infertility. Furthermore, upstream pathways that regulate meiotic initiation will be discussed in the context of …
This review highlights the mechanisms of meiotic initiation and meiotic prophase progression from the point of the gene expression program a …
Epsilon tubulin is an essential determinant of microtubule-based structures in male germ cells.
Stathatos GG, Merriner DJ, O'Connor AE, Zenker J, Dunleavy JE, O'Bryan MK. Stathatos GG, et al. EMBO Rep. 2024 Jun;25(6):2722-2742. doi: 10.1038/s44319-024-00159-w. Epub 2024 May 21. EMBO Rep. 2024. PMID: 38773322 Free PMC article.
We show that TUBE1 is essential for the function of multiple complex microtubule arrays, including the meiotic spindle, axoneme and manchette and in its absence, there is a dramatic loss of germ cells and male sterility. Moreover, we provide evidence for the interplay betw …
We show that TUBE1 is essential for the function of multiple complex microtubule arrays, including the meiotic spindle, axoneme and manchett …
Evaluation of telomere length and telomerase activity on predicting in vitro fertilization treatment outcomes.
Fragkiadaki P, Kouvidi E, Angelaki A, Nikolopoulou D, Vakonaki E, Tsatsakis A. Fragkiadaki P, et al. J Assist Reprod Genet. 2024 Jun;41(6):1463-1473. doi: 10.1007/s10815-024-03117-6. Epub 2024 May 2. J Assist Reprod Genet. 2024. PMID: 38695985 Free PMC article. Review.
Cellular senescence, along with other exogenous and mainly environmental factors, can enhance telomere wear, further shortening their ends and may also affect reproductive aging. IVF is a common fertility treatment caused by female reasons (age, ovulation disorders, damage …
Cellular senescence, along with other exogenous and mainly environmental factors, can enhance telomere wear, further shortening their ends a …
Analysis of factors affecting pregnancy rate after laparoscopic surgery for infertility associated with endometriosis.
Zhang J, Lian N, Guo S, Xie X. Zhang J, et al. Eur J Obstet Gynecol Reprod Biol. 2024 Jun;297:214-220. doi: 10.1016/j.ejogrb.2024.04.034. Epub 2024 Apr 27. Eur J Obstet Gynecol Reprod Biol. 2024. PMID: 38691973 Free article.
OBJECTIVE: To analyze the factors that might influence the pregnancy rate in patients with infertility related to endometriosis (EMs) after undergoing laparoscopic surgery, providing guidance for our clinical diagnostic and therapeutic decision-making. ...RESULTS: The over …
OBJECTIVE: To analyze the factors that might influence the pregnancy rate in patients with infertility related to endometriosis (EMs) …
Obesity and male fertility disorders.
Cannarella R, Crafa A, Curto R, Condorelli RA, La Vignera S, Calogero AE. Cannarella R, et al. Mol Aspects Med. 2024 Jun;97:101273. doi: 10.1016/j.mam.2024.101273. Epub 2024 Apr 8. Mol Aspects Med. 2024. PMID: 38593513 Free article. Review.
In this article, we provide a comprehensive and critical analysis of studies exploring the association between obesity and male reproductive function, to evaluate the frequency of this association, and establish the effects of increased body weight on conventional and biof …
In this article, we provide a comprehensive and critical analysis of studies exploring the association between obesity and male reproduct
Intrauterine insemination: prognostic factors.
Dias CMF, Vitorino GBT, Furlan SMP, Reis RMD, Silva ACJSRE, Mendes MC, Ferriani RA, Navarro PA. Dias CMF, et al. JBRA Assist Reprod. 2024 Jun 1;28(2):254-262. doi: 10.5935/1518-0557.20240017. JBRA Assist Reprod. 2024. PMID: 38546118 Free PMC article.
RESULTS: The ovulation induction protocol using gonadotropins plus letrozole (p=0.0097; OR 4.3286, CI 1.3040 - 14.3684) and post-capacitation progressive sperm 5million/mL (p=0.0253) showed a statistically significant correlation with the live birth rate. Female and male age, eti …
RESULTS: The ovulation induction protocol using gonadotropins plus letrozole (p=0.0097; OR 4.3286, CI 1.3040 - 14.3684) and post-capacitatio …
Proposed classification of adenomyosis in Infertile women to simplify management options undergoing ART.
Tandulwadkar S, Mishra S, Langde S, Pandey M, Gandhi R. Tandulwadkar S, et al. JBRA Assist Reprod. 2024 Jun 1;28(2):353-357. doi: 10.5935/1518-0557.20240015. JBRA Assist Reprod. 2024. PMID: 38530759 Free PMC article.
OBJECTIVE: Adenomyosis associated with subfertility is a situation of a dilemma for the treating clinician as the treatment is highly controversial and there remains an overall lack of consensus regarding the value of conservative surgery with or without medical management to imp …
OBJECTIVE: Adenomyosis associated with subfertility is a situation of a dilemma for the treating clinician as the treatment is highly contro …
Prolactin-secreting tumors, dopamine agonists and pregnancy: a longitudinal experience of a tertiary neuroendocrine center.
Prencipe N, Bona C, Cuboni D, Berton AM, Bioletto F, Varaldo E, Aversa LS, Sibilla M, Gasco V, Ghigo E, Grottoli S. Prencipe N, et al. Pituitary. 2024 Jun;27(3):269-276. doi: 10.1007/s11102-024-01384-1. Epub 2024 Mar 18. Pituitary. 2024. PMID: 38499816 Free PMC article.
PURPOSE: Prolactin (PRL)-secreting tumours are associated with infertility and can be reverted by dopamine agonist (DA) therapy. The suspension of DA is recommended once pregnancy is established, as all DAs cross the placenta. ...
PURPOSE: Prolactin (PRL)-secreting tumours are associated with infertility and can be reverted by dopamine agonist (DA) therapy. The …
Antimüllerian hormone levels and IVF outcomes in polycystic ovary syndrome women: a scoping review.
Delamuta LC, Fassolas G, Dias JA, Henrique LFO, Izzo FPM, Izzo CR. Delamuta LC, et al. JBRA Assist Reprod. 2024 Jun 1;28(2):299-305. doi: 10.5935/1518-0557.20230059. JBRA Assist Reprod. 2024. PMID: 38446747 Free PMC article. Review.
Polycystic ovary syndrome (PCOS) is an endocrine condition that affects women of reproductive age worldwide, and it is associated with high levels of AMH. ...
Polycystic ovary syndrome (PCOS) is an endocrine condition that affects women of reproductive age worldwide, and it is associated wit …
Predictive Factors for the Formation of Viable Embryos in Subfertile Patients with Diminished Ovarian Reserve: A Clinical Prediction Study.
Feng K, Zhang Z, Wu L, Zhu L, Li X, Li D, Ruan L, Luo Y. Feng K, et al. Reprod Sci. 2024 Jun;31(6):1747-1756. doi: 10.1007/s43032-024-01469-z. Epub 2024 Feb 26. Reprod Sci. 2024. PMID: 38409494 Free PMC article.
A retrospective analysis was conducted on 445 DOR patients who underwent in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) at the Reproductive Center of Yulin Maternal and Child Health Hospital from January 2019 to January 2023. ...
A retrospective analysis was conducted on 445 DOR patients who underwent in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI …
Building Healthy Babies: A Mixed-Methods Needs Assessment for a Pre-Conception Program in Ontario.
Li A, Mehra VM, Jones C, Selk A, Ray J, Morson N, Cohen E, Roifman M, Snelgrove JW, Greenblatt EM. Li A, et al. J Obstet Gynaecol Can. 2024 Jun;46(6):102417. doi: 10.1016/j.jogc.2024.102417. Epub 2024 Feb 23. J Obstet Gynaecol Can. 2024. PMID: 38403165 Free article.
An individual appointment with a primary care provider was the favoured program format per survey responses, whereas a virtual format with an interactive component was preferred among focus group participants. Important topics to include were pre-conception health (infertility
An individual appointment with a primary care provider was the favoured program format per survey responses, whereas a virtual format with a …
Sperm Preparation with Microfluidic Sperm Sorting Chip May Improve Intracytoplasmic Sperm Injection Outcomes Compared to Density Gradient Centrifugation.
Banti M, Van Zyl E, Kafetzis D. Banti M, et al. Reprod Sci. 2024 Jun;31(6):1695-1704. doi: 10.1007/s43032-024-01483-1. Epub 2024 Feb 23. Reprod Sci. 2024. PMID: 38393626 Free PMC article.
Binary logistic regression analysis assessed the relationship between female age, the presence of male factor infertility, and euploidy rates. Blastocyst, utilization, and euploidy rates were significantly higher for cycles using FERTILE PLUS compared to DGC (76% vs 56%, p …
Binary logistic regression analysis assessed the relationship between female age, the presence of male factor infertility, and euploi …
Follicular fluid concentration of soluble Human-G Leukocytic Antigen (sHLA-G) in in vitro fertilization cycles of women with and without peritoneal endometriosis.
Bezerra GP, Genro VK, Souza CAB, Cunha-Filho JS. Bezerra GP, et al. JBRA Assist Reprod. 2024 Jun 1;28(2):263-268. doi: 10.5935/1518-0557.20240012. JBRA Assist Reprod. 2024. PMID: 38381778 Free PMC article.
RESULTS: Groups were comparables in terms of age, the number of follicles, AMH, FSH and all included reproductive outcomes. There was no association between sHLA-G concentrations and the average score of the generated embryos (p>0.05). ...CONCLUSIONS: Patients with peri …
RESULTS: Groups were comparables in terms of age, the number of follicles, AMH, FSH and all included reproductive outcomes. There was …
The Vaginal Microbiome Changes During Various Fertility Treatments.
van den Tweel MM, van den Munckhof EHA, van der Zanden M, Molijn A, van Lith JMM, Boers KE. van den Tweel MM, et al. Reprod Sci. 2024 Jun;31(6):1593-1600. doi: 10.1007/s43032-024-01484-0. Epub 2024 Feb 20. Reprod Sci. 2024. PMID: 38379070 Free PMC article.
A Novel Method to Repair Thin Endometrium and Restore Fertility Based on Menstruation-Derived Stem Cell.
Chen K, Wang H, Zhao X, Wang J, Jin Q, Tong X, Zheng S. Chen K, et al. Reprod Sci. 2024 Jun;31(6):1662-1673. doi: 10.1007/s43032-024-01458-2. Epub 2024 Jan 31. Reprod Sci. 2024. PMID: 38294669 Free PMC article.
Thin endometrium (TE), which mainly occurs as a result of severe damage to the endometrial basalis, is one of the prominent etiologies of menstrual abnormalities, infertility, and recurrent miscarriage in women. Previous studies have demonstrated that mesenchymal stem cell …
Thin endometrium (TE), which mainly occurs as a result of severe damage to the endometrial basalis, is one of the prominent etiologies of me …
Detecting partial premature ovulation during follicular aspiration compromises the quantity, but not the quality, of the oocytes retrieved in stimulated in vitro fertilization (IVF) cycles.
Gómez VH, Rodríguez-Varela C, Labarta E, Bosch E. Gómez VH, et al. JBRA Assist Reprod. 2024 Jun 1;28(2):240-246. doi: 10.5935/1518-0557.20240003. JBRA Assist Reprod. 2024. PMID: 38289203 Free PMC article.
This study constitutes a retrospective analysis performed in an infertility clinic (Spain) during 2016-2021 with patients undergoing OPU after controlled ovarian hyperstimulation for an in vitro fertilization (IVF) treatment. ...
This study constitutes a retrospective analysis performed in an infertility clinic (Spain) during 2016-2021 with patients undergoing …
A comparison of pregnancy outcomes and congenital malformations in offspring between patients undergoing intracytoplasmic sperm injection and conventional in vitro fertilization: a retrospective cohort study.
Zhang N, Tian T, Li J, Zhu X, Jiesisibieke D, Fang S, Liu P, Li R, Qiao J, Yang R. Zhang N, et al. Fertil Steril. 2024 Jun;121(6):982-990. doi: 10.1016/j.fertnstert.2024.01.025. Epub 2024 Jan 20. Fertil Steril. 2024. PMID: 38253118 Free article.
PATIENT(S): Data were collected from couples who underwent conventional IVF or ICSI from January 2009 to December 2019 at the Center for Reproductive Medicine of Peking University Third Hospital in the People's Republic of China. ...
PATIENT(S): Data were collected from couples who underwent conventional IVF or ICSI from January 2009 to December 2019 at the Center for …
The relationship between cesarean delivery and fecundability: a population-based cohort study.
Sima YT, Magnus MC, Kvalvik LG, Morken NH, Klungsøyr K, Skjærven R, Sørbye LM. Sima YT, et al. Am J Obstet Gynecol. 2024 Jun;230(6):667.e1-667.e21. doi: 10.1016/j.ajog.2023.10.029. Epub 2023 Oct 19. Am J Obstet Gynecol. 2024. PMID: 37863159 Free article.
We estimated the fecundability ratio (per cycle probability of pregnancy) and relative risk of infertility (time to pregnancy 12 months) by mode of delivery in the previous delivery among 42,379 women. ...CONCLUSION: Among women with more than 1 child, those who had a prev …
We estimated the fecundability ratio (per cycle probability of pregnancy) and relative risk of infertility (time to pregnancy 12 mont …
Smoothelin-like protein 1 promotes insulin sensitivity and modulates the contractile properties of endometrial epithelial cells with insulin resistance.
Keller I, Ungvári Á, Kinter R, Szalmás F, Kókai E, Lontay B. Keller I, et al. Front Endocrinol (Lausanne). 2024 May 31;15:1375771. doi: 10.3389/fendo.2024.1375771. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38883605 Free PMC article.
INTRODUCTION: The incidence of infertility is significantly higher in women with diseases linked to impaired glucose homeostasis, such as insulin resistance. ...In addition, SMTNL-1 after phosphorylation at Ser301 by protein kinase A translocates to the nucleus and functio …
INTRODUCTION: The incidence of infertility is significantly higher in women with diseases linked to impaired glucose homeostasis, suc …
Adherence to dietary recommendations mediates the effect of affective temperaments on infertility treatment outcomes.
Szabo G, Szigeti F J, Sipos M, Varbiro S, Gonda X. Szabo G, et al. Sci Rep. 2024 May 31;14(1):12544. doi: 10.1038/s41598-024-63343-x. Sci Rep. 2024. PMID: 38822094 Free PMC article.
The aim of this retrospective cohort study was to evaluate whether adherence to physician-prescribed diet and physical activity recommendations mediates the effect of affective temperaments on infertility treatment outcomes. Among 308 women who underwent infertility
The aim of this retrospective cohort study was to evaluate whether adherence to physician-prescribed diet and physical activity recommendati …
Chronic endometritis and the endometrial microbiota: implications for reproductive success in patients with recurrent implantation failure.
Zhang H, Zou H, Zhang C, Zhang S. Zhang H, et al. Ann Clin Microbiol Antimicrob. 2024 May 30;23(1):49. doi: 10.1186/s12941-024-00710-6. Ann Clin Microbiol Antimicrob. 2024. PMID: 38816832 Free PMC article.
BACKGROUND: Chronic endometritis (CE) is associated with poor reproductive outcomes, yet the role of endometrial microbiota in patients with recurrent implantation failure (RIF) and CE remains unclear. ...CONCLUSION: RIF patients with CE exhibit distinct endometrial microb …
BACKGROUND: Chronic endometritis (CE) is associated with poor reproductive outcomes, yet the role of endometrial microbiota in patien …
Efficacy of endometrial receptivity testing for recurrent implantation failure in patients with euploid embryo transfers: study protocol for a randomized controlled trial.
Lu Y, Mao X, He Y, Wang Y, Sun Y. Lu Y, et al. Trials. 2024 May 28;25(1):348. doi: 10.1186/s13063-024-08125-6. Trials. 2024. PMID: 38807239 Free PMC article.
BACKGROUND: Embryo implantation remains a critical barrier in assisted reproductive technologies. One of the main causes of unsuccessful embryo implantation is window of implantation (WOI) displacement, particularly in patients with recurrent implantation failure (RIF). .. …
BACKGROUND: Embryo implantation remains a critical barrier in assisted reproductive technologies. One of the main causes of unsuccess …
Safety profiles of offspring born from early-follicular long-acting GnRH agonist protocol and daily mid-luteal GnRH agonist protocol: a retrospective study.
Du L, Song J, Fan W, Ye T, Kong H. Du L, et al. BMC Pregnancy Childbirth. 2024 May 28;24(1):393. doi: 10.1186/s12884-024-06589-7. BMC Pregnancy Childbirth. 2024. PMID: 38807043 Free PMC article.
BACKGROUND: The gonadotropin hormone-releasing hormone agonists (GnRH-a) have been widely used for controlled ovarian stimulation in assisted reproductive technology (ART). The early-follicular long-acting GnRH-a long protocol (EFL) and the luteal phase short-acting GnRH-a …
BACKGROUND: The gonadotropin hormone-releasing hormone agonists (GnRH-a) have been widely used for controlled ovarian stimulation in assiste …
Investigating GABA Neuron-Specific Androgen Receptor Knockout in two Hyperandrogenic Models of PCOS.
Sucquart IE, Coyle C, Rodriguez Paris V, Prescott M, Glendining KA, Potapov K, Begg DP, Gilchrist RB, Walters KA, Campbell RE. Sucquart IE, et al. Endocrinology. 2024 May 27;165(7):bqae060. doi: 10.1210/endocr/bqae060. Endocrinology. 2024. PMID: 38788194 Free PMC article.
Androgen excess is a hallmark feature of polycystic ovary syndrome (PCOS), the most common form of anovulatory infertility. Clinical and preclinical evidence links developmental or chronic exposure to hyperandrogenism with programming and evoking the reproductive an …
Androgen excess is a hallmark feature of polycystic ovary syndrome (PCOS), the most common form of anovulatory infertility. Clinical …
Clomiphene Citrate Administered in Periconception Phase Causes Fetal Loss and Developmental Impairment in Mice.
Chin PY, Chan HY, Kieffer TEC, Prins JR, Russell DL, Davies MJ, Robertson SA. Chin PY, et al. Endocrinology. 2024 May 27;165(7):bqae047. doi: 10.1210/endocr/bqae047. Endocrinology. 2024. PMID: 38608138 Free PMC article.
A dose-dependent adverse effect of clomiphene citrate given twice in the 36 hours after mating was seen, with a moderate dose of 0.75 mg/kg sufficient to cause altered reproductive outcomes in 3 independent cohorts. Viable pregnancy was reduced by 30%, late gestation fetal …
A dose-dependent adverse effect of clomiphene citrate given twice in the 36 hours after mating was seen, with a moderate dose of 0.75 mg/kg …
Effects of glucagon-like peptide-1 receptor agonists on spermatogenesis-related gene expression in mouse testis and testis-derived cell lines.
Iida M, Asano A. Iida M, et al. J Vet Med Sci. 2024 May 25;86(5):555-562. doi: 10.1292/jvms.24-0042. Epub 2024 Apr 1. J Vet Med Sci. 2024. PMID: 38556323 Free PMC article.
Incretins have recently been reported to have extrapancreatic actions, and they are anticipated to have potential efficacy for conditions such as male infertility as well as diabetes. However, the effects of incretins on male reproductive function remain unclear. .. …
Incretins have recently been reported to have extrapancreatic actions, and they are anticipated to have potential efficacy for conditions su …
Identifying suitable methods for evaluating the sterilizing effects of pyriproxyfen on adult malaria vectors: a comparison of the oviposition and ovary dissection methods.
Myers A, Fagbohoun J, Houetohossou G, Ndombidje B, Govoetchan R, Todjinou D, Ngufor C. Myers A, et al. Malar J. 2024 May 24;23(1):164. doi: 10.1186/s12936-024-04983-2. Malar J. 2024. PMID: 38789998 Free PMC article.
BACKGROUND: Nets containing pyriproxyfen, an insect growth regulator that sterilizes adult mosquitoes, have become available for malaria control. ...RESULTS: The total number of An. gambiae s.l. mosquitoes assessed for the sterilizing effects of pyriproxyfen were 17 …
BACKGROUND: Nets containing pyriproxyfen, an insect growth regulator that sterilizes adult mosquitoes, have become available for mala …
Molecular Insights into Female Hybrid Sterility in Interspecific Crosses between Drosophila melanogaster and Drosophila simulans.
Kotov AA, Adashev VE, Kombarov IA, Bazylev SS, Shatskikh AS, Olenina LV. Kotov AA, et al. Int J Mol Sci. 2024 May 23;25(11):5681. doi: 10.3390/ijms25115681. Int J Mol Sci. 2024. PMID: 38891872 Free PMC article.
Species of the genus Drosophila have served as favorite models in speciation studies; however, genetic factors of interspecific reproductive incompatibility are under-investigated. Here, we performed an analysis of hybrid female sterility by crossing Drosophila mela …
Species of the genus Drosophila have served as favorite models in speciation studies; however, genetic factors of interspecific reproduct
The first two blastomeres contribute unequally to the human embryo.
Junyent S, Meglicki M, Vetter R, Mandelbaum R, King C, Patel EM, Iwamoto-Stohl L, Reynell C, Chen DY, Rubino P, Arrach N, Paulson RJ, Iber D, Zernicka-Goetz M. Junyent S, et al. Cell. 2024 May 23;187(11):2838-2854.e17. doi: 10.1016/j.cell.2024.04.029. Epub 2024 May 13. Cell. 2024. PMID: 38744282 Free article.
Adar Regulates Drosophila melanogaster Spermatogenesis via Modulation of BMP Signaling.
Zhang Q, Fan X, Fu F, Zhu Y, Luo G, Chen H. Zhang Q, et al. Int J Mol Sci. 2024 May 22;25(11):5643. doi: 10.3390/ijms25115643. Int J Mol Sci. 2024. PMID: 38891830 Free PMC article.
The dynamic process of Drosophila spermatogenesis involves asymmetric division, mitosis, and meiosis, which ultimately results in the production of mature spermatozoa. Disorders of spermatogenesis can lead to infertility in males. ADAR (adenosine deaminase acting on RNA) m …
The dynamic process of Drosophila spermatogenesis involves asymmetric division, mitosis, and meiosis, which ultimately results in the produc …
The profile of steroid hormones in human fetal and adult ovaries.
Vazakidou P, Evangelista S, Li T, Lecante LL, Rosenberg K, Koekkoek J, Salumets A, Velthut-Meikas A, Damdimopoulou P, Mazaud-Guittot S, Fowler PA, Leonards PEG, van Duursen MBM. Vazakidou P, et al. Reprod Biol Endocrinol. 2024 May 22;22(1):60. doi: 10.1186/s12958-024-01233-7. Reprod Biol Endocrinol. 2024. PMID: 38778396 Free PMC article.
Steroid hormone levels are fundamental for the normal development and function of the human reproductive system, including the ovary. This study aims to elucidate steroidogenesis at different life-stages in human ovaries. METHODS: We have developed a sensitive and specific …
Steroid hormone levels are fundamental for the normal development and function of the human reproductive system, including the ovary. …
Pseudopregnant mice generated from Piwil1 deficiency sterile mice.
Xie S, Qin R, Zeng W, Li J, Lai Y. Xie S, et al. PLoS One. 2024 May 21;19(5):e0296414. doi: 10.1371/journal.pone.0296414. eCollection 2024. PLoS One. 2024. PMID: 38771805 Free PMC article.
In this study, we generated C57BL/6J mice (Piwil1 D633A-INS99, Piwil1mt/mt) with a 99-base insertion in the Miwi (Piwil1) gene using CRISPR/Cas9 technology and showed that Piwil1mt/+ heterozygous mice were normally fertile and that homozygous Piwil1mt/mt males were sterile
In this study, we generated C57BL/6J mice (Piwil1 D633A-INS99, Piwil1mt/mt) with a 99-base insertion in the Miwi (Piwil1) gene using CRISPR/ …
[Reproductive Health-Oriented Development in Assisted Reproductive Technologies].
Hu P, Pan J, Liu X, Huang H. Hu P, et al. Sichuan Da Xue Xue Bao Yi Xue Ban. 2024 May 20;55(3):501-506. doi: 10.12182/20240560401. Sichuan Da Xue Xue Bao Yi Xue Ban. 2024. PMID: 38948299 Free PMC article. Review. Chinese.
Assisted reproductive technologies (ARTs) are core components of the field of reproductive medicine, encompassing multiple pivotal stages of early development from gamete maturation and fertilization to embryo development. ...In addition, we reevaluated their roles …
Assisted reproductive technologies (ARTs) are core components of the field of reproductive medicine, encompassing multiple piv …
[Analysis of Risk Factors for Recurrent Pregnancy Loss in Patients Undergoing in vitro Fertilization-Embryo Transfer].
Cao Y, Li Y, Pan P, DU T, Yang D, Zhao X. Cao Y, et al. Sichuan Da Xue Xue Bao Yi Xue Ban. 2024 May 20;55(3):724-730. doi: 10.12182/20240560102. Sichuan Da Xue Xue Bao Yi Xue Ban. 2024. PMID: 38948280 Free PMC article. Chinese.
METHODS: This retrospective case-controlled study included RPL patients who underwent IVF-ET treatment at Sun Yat-sen Memorial Hospital, Sun Yat-sen University, between January 2012 and March 2021 as the case cohort, compared with women receiving assisted reproductive trea …
METHODS: This retrospective case-controlled study included RPL patients who underwent IVF-ET treatment at Sun Yat-sen Memorial Hospital, Sun …
[The Roles of N6-Methyladenosine Modification and Its Regulators in Male Reproduction].
Jiang T, Zhang X, Xu W. Jiang T, et al. Sichuan Da Xue Xue Bao Yi Xue Ban. 2024 May 20;55(3):527-534. doi: 10.12182/20240560103. Sichuan Da Xue Xue Bao Yi Xue Ban. 2024. PMID: 38948273 Free PMC article. Review. Chinese.
Most men diagnosed with infertility exhibit symptoms such as oligospermia, asthenospermia, azoospermia, and compromised sperm quality. ...In mammals, the aberrant methylation modification of m(6)A on mRNA is associated with a variety of diseases, including male infertil
Most men diagnosed with infertility exhibit symptoms such as oligospermia, asthenospermia, azoospermia, and compromised sperm quality …
The essential role of adenine nucleotide translocase 4 on male reproductive function in mice.
Yang F, Yang X, Zhu H, Wang X, Liao X, Fu Y, Fu T, Chen X, Sysa A, Lyu J, Zhou H. Yang F, et al. Braz J Med Biol Res. 2024 May 20;57:e13590. doi: 10.1590/1414-431X2024e13590. eCollection 2024. Braz J Med Biol Res. 2024. PMID: 38808891 Free PMC article.
Our observations demonstrated that Ant4-deficiency led to infertility and impaired testicular development, which was further investigated by evaluating testicular oxidative stress, autophagy, and inflammation. ...
Our observations demonstrated that Ant4-deficiency led to infertility and impaired testicular development, which was further investig …
The mechanoreceptor Piezo is required for spermatogenesis in Bombyx mori.
Zhang Z, Liu X, Hu B, Chen K, Yu Y, Sun C, Zhu D, Bai H, Palli SR, Tan A. Zhang Z, et al. BMC Biol. 2024 May 20;22(1):118. doi: 10.1186/s12915-024-01916-y. BMC Biol. 2024. PMID: 38769528 Free PMC article.
Moreover, we show that the deformed eupyrene sperm bundles fail to migrate from the testes, resulting in male infertility due to the absence of eupyrene sperm in the bursa copulatrix and spermatheca. ...
Moreover, we show that the deformed eupyrene sperm bundles fail to migrate from the testes, resulting in male infertility due to the …
Smokeless tobacco consumption among women of reproductive age: a systematic review and meta-analysis.
Itumalla R, Khatib MN, Gaidhane S, Zahiruddin QS, Gaidhane AM, Neyazi A, Hassam AF, Satapathy P, Rustagi S, Kukreti N, Padhi BK. Itumalla R, et al. BMC Public Health. 2024 May 20;24(1):1361. doi: 10.1186/s12889-024-18840-z. BMC Public Health. 2024. PMID: 38769491 Free PMC article.
Our analysis shows a significant prevalence of SLT use in women of reproductive age, especially in low socioeconomic and developing countries like India, Pakistan, and Nepal. For women of reproductive age, the use of smokeless tobacco (SLT) can lead to infertilit
Our analysis shows a significant prevalence of SLT use in women of reproductive age, especially in low socioeconomic and developing c …
Conserved genes regulating human sex differentiation, gametogenesis and fertilization.
Fakhro KA, Awwad J, Garibova S, Saraiva LR, Avella M. Fakhro KA, et al. J Transl Med. 2024 May 19;22(1):473. doi: 10.1186/s12967-024-05162-2. J Transl Med. 2024. PMID: 38764035 Free PMC article. Review.
Infertility is a reproductive disorder that includes various conditions affecting a couple's ability to achieve a healthy pregnancy. ...Finally, we introduce new model systems for the study of human reproductive biology and highlight the importance of studyin
Infertility is a reproductive disorder that includes various conditions affecting a couple's ability to achieve a healthy preg
Cytosolic and Acrosomal pH Regulation in Mammalian Sperm.
Chávez JC, Carrasquel-Martínez G, Hernández-Garduño S, Matamoros Volante A, Treviño CL, Nishigaki T, Darszon A. Chávez JC, et al. Cells. 2024 May 17;13(10):865. doi: 10.3390/cells13100865. Cells. 2024. PMID: 38786087 Free PMC article. Review.
Examples include the Ca(2+) channel CatSper and the K(+) channel Slo3. The absence of these channels leads to male infertility. This review outlines the main transport elements involved in pH regulation, including cytosolic and acrosomal pH, that participate in these compl …
Examples include the Ca(2+) channel CatSper and the K(+) channel Slo3. The absence of these channels leads to male infertility. This …
Platelet-rich plasma (PRP) treatment of the ovaries significantly improves fertility parameters and reproductive outcomes in diminished ovarian reserve patients: a systematic review and meta-analysis.
Éliás M, Kónya M, Kekk Z, Turan C, das Virgens IPA, Tóth R, Keszthelyi M, Hegyi P, Várbíró S, Sipos M. Éliás M, et al. J Ovarian Res. 2024 May 17;17(1):104. doi: 10.1186/s13048-024-01423-2. J Ovarian Res. 2024. PMID: 38760869 Free PMC article.
INTRODUCTION: The incidence of infertility caused by diminished ovarian reserve has become a significant problem worldwide. ...
INTRODUCTION: The incidence of infertility caused by diminished ovarian reserve has become a significant problem worldwide. ...
Metabolic landscape and pathogenic insights: a comprehensive analysis of high ovarian response in infertile women undergoing in vitro fertilization.
Ruan LL, Lv XY, Hu YL, Chen MX, Jing-Tang, Zhong ZH, Bao MH, Fu LJ, Luo X, Yu SM, Wan Q, Ding YB. Ruan LL, et al. J Ovarian Res. 2024 May 17;17(1):105. doi: 10.1186/s13048-024-01411-6. J Ovarian Res. 2024. PMID: 38760835 Free PMC article.
METHODS: We categorized 145 infertile women into two main groups: the CON infertility group from tubal infertility patients and the Polycystic Ovary Syndrome (PCOS) infertility group. ...CONCLUSION: Our study highlights significant metabolite differences betw …
METHODS: We categorized 145 infertile women into two main groups: the CON infertility group from tubal infertility patients an …
Interaction between Chromodomain Y-like Protein and Androgen Receptor Signaling in Sertoli Cells Accounts for Spermatogenesis.
Lan KC, Cheng YH, Chang YC, Wei KT, Weng PL, Kang HY. Lan KC, et al. Cells. 2024 May 16;13(10):851. doi: 10.3390/cells13100851. Cells. 2024. PMID: 38786072 Free PMC article.
These findings provide insights into novel molecular mechanisms targeting the AR-CDYL signaling pathway, which may have implications for developing new therapeutic strategies for male infertility....
These findings provide insights into novel molecular mechanisms targeting the AR-CDYL signaling pathway, which may have implications for dev …
The lack of Tex44 causes severe subfertility with flagellar abnormalities in male mice.
Dupuis S, Girault MS, Le Beulze M, Ialy-Radio C, Bermúdez-Guzmán L, Ziyyat A, Barbaux S. Dupuis S, et al. Cell Mol Biol Lett. 2024 May 15;29(1):74. doi: 10.1186/s11658-024-00587-5. Cell Mol Biol Lett. 2024. PMID: 38750428 Free PMC article.
Within this locus, we identified a new candidate gene that could be implicated in a reproductive phenotype: Tex44 (Testis-expressed protein 44). We thus performed a CRISPR/Cas9-mediated complete deletion of this gene in mice in order to study its function. ...
Within this locus, we identified a new candidate gene that could be implicated in a reproductive phenotype: Tex44 (Testis-expressed p …
Successful pregnancy with intracytoplasmic sperm injection after bacterial contamination of embryo culture in in vitro fertilization: a case report.
Berkes-Bara E, Nemes A, Dudas B, Joo K, Murber A, Fekecs G, Urbancsek J, Fancsovits P. Berkes-Bara E, et al. J Med Case Rep. 2024 May 15;18(1):247. doi: 10.1186/s13256-024-04521-3. J Med Case Rep. 2024. PMID: 38745332 Free PMC article.
A 36-year-old Hungarian woman and her 37-year-old Hungarian partner came to our department. They had two normal births followed by 2 years of infertility. The major causes of infertility were a closed fallopian tube and asthenozoospermia. ...
A 36-year-old Hungarian woman and her 37-year-old Hungarian partner came to our department. They had two normal births followed by 2 years o …
Cyto- and Histopographic Assessment of CPA3-Positive Testicular Mast Cells in Obstructive and Non-Obstructive Azoospermia.
Atiakshin D, Kulchenko N, Kostin A, Ignatyuk M, Protasov A, Klabukov I, Baranovskii D, Faniev M, Korovyakova E, Chekmareva I, Buchwalow I, Tiemann M. Atiakshin D, et al. Cells. 2024 May 14;13(10):833. doi: 10.3390/cells13100833. Cells. 2024. PMID: 38786055 Free PMC article.
Infertility is an important personal and society disease, of which the male factor represents half of all causes. One of the aspects less studied in male infertility is the immunological testicular microenvironment. Mast cells (MCs), having high potential for regula
Infertility is an important personal and society disease, of which the male factor represents half of all causes. One of the aspects
Effect of cytoplasmic fragmentation on embryo development, quality, and pregnancy outcome: a systematic review of the literature.
Yazdani A, Halvaei I, Boniface C, Esfandiari N. Yazdani A, et al. Reprod Biol Endocrinol. 2024 May 14;22(1):55. doi: 10.1186/s12958-024-01217-7. Reprod Biol Endocrinol. 2024. PMID: 38745305 Free PMC article. Review.
The role of cytoplasmic fragmentation in human embryo development and reproductive potential is widely recognized, albeit without standard definition nor agreed upon implication. ...
The role of cytoplasmic fragmentation in human embryo development and reproductive potential is widely recognized, albeit without sta …
Single-cell and spatial transcriptomic investigation reveals the spatiotemporal specificity of the beta-defensin gene family during mouse sperm maturation.
Zhang G, Sun Y, Guan M, Liu M, Sun S. Zhang G, et al. Cell Commun Signal. 2024 May 14;22(1):267. doi: 10.1186/s12964-024-01637-3. Cell Commun Signal. 2024. PMID: 38745232 Free PMC article.
Low sperm motility is a significant contributor to male infertility. beta-defensins have been implicated in host defence and the acquisition of sperm motility; however, the regulatory mechanisms governing their gene expression patterns and functions remain poorly understoo …
Low sperm motility is a significant contributor to male infertility. beta-defensins have been implicated in host defence and the acqu …
Defining Trimester-Specific Reference Intervals for Thyroid Hormones: Insights from a Bulgarian Monocenter Study.
Yanachkova V, Staynova R, Naseva EK. Yanachkova V, et al. Medicina (Kaunas). 2024 May 13;60(5):801. doi: 10.3390/medicina60050801. Medicina (Kaunas). 2024. PMID: 38792984 Free PMC article.
Differences in population characteristics, including ethnicity, socio-economic factors, iodine prophylaxis, and obesity, emphasize the need to establish trimester-specific TSH ranges for women of reproductive age in the respective region or center. The aim of the present s …
Differences in population characteristics, including ethnicity, socio-economic factors, iodine prophylaxis, and obesity, emphasize the need …
Prevalence of different variations of non-consented care during the childbirth process in Mexico by geographical regions: comparing ENDIREH survey data from 2016 to 2021.
Marian M, Barker KM, Reed E, McClain AC, Lundgren R, Hurst S, Pérez RL. Marian M, et al. BMC Pregnancy Childbirth. 2024 May 13;24(1):353. doi: 10.1186/s12884-024-06549-1. BMC Pregnancy Childbirth. 2024. PMID: 38741050 Free PMC article.
METHODS: We measured the prevalence of non-consented care and three of its variations, forced sterilization or contraception, forced cesarean section, and forced consent on paperwork, during childbirth in Mexico for 2016 (N = 24,036) and 2021 (N = 19,322) using data from M …
METHODS: We measured the prevalence of non-consented care and three of its variations, forced sterilization or contraception, forced …
Surgical treatment and reproductive outcomes in caesarean scar pregnancy at a single center.
Lei Y, Du X, Liu Y, Le F, Zhou J. Lei Y, et al. Reprod Biol Endocrinol. 2024 May 11;22(1):54. doi: 10.1186/s12958-024-01225-7. Reprod Biol Endocrinol. 2024. PMID: 38734672 Free PMC article.
BACKGROUND: To investigate factors associated with different reproductive outcomes in patients with Caesarean scar pregnancies (CSPs). ...Abortion after CSP is a risk factor for RCSP. No significant difference in reproductive outcomes was observed between the patien …
BACKGROUND: To investigate factors associated with different reproductive outcomes in patients with Caesarean scar pregnancies (CSPs) …
Loss of PBX1 function in Leydig cells causes testicular dysgenesis and male sterility.
Wang FC, Zhang XN, Wu SX, He Z, Zhang LY, Yang QE. Wang FC, et al. Cell Mol Life Sci. 2024 May 9;81(1):212. doi: 10.1007/s00018-024-05249-5. Cell Mol Life Sci. 2024. PMID: 38724675 Free PMC article.
A functional deficiency in Leydig cells often causes severe reproductive disorders; however, the transcriptional programs underlying the fate decisions and steroidogenesis of these cells have not been fully defined. ...Conditional deletion of Pbx1 in Leydig cells caused sp …
A functional deficiency in Leydig cells often causes severe reproductive disorders; however, the transcriptional programs underlying …
USP11 regulates proliferation and apoptosis of human spermatogonial stem cells via HOXC5-mediated canonical WNT/β-catenin signaling pathway.
Gao J, Xu Z, Song W, Huang J, Liu W, He Z, He L. Gao J, et al. Cell Mol Life Sci. 2024 May 9;81(1):211. doi: 10.1007/s00018-024-05248-6. Cell Mol Life Sci. 2024. PMID: 38722330 Free PMC article.
Nevertheless, it remains largely unknown about key genes and signaling pathways that regulate fate determinations of human SSCs and male infertility. In this study, we explored the expression, function, and mechanism of USP11 in controlling the proliferation and apoptosis …
Nevertheless, it remains largely unknown about key genes and signaling pathways that regulate fate determinations of human SSCs and male …
Regulation of early spermatogenesis in the giant prawn Macrobrachium rosenbergii by a GCL homolog†.
Molcho J, Albagly D, Levy T, Manor R, Aflalo ED, Alfaro-Montoya J, Sagi A. Molcho J, et al. Biol Reprod. 2024 May 9;110(5):1000-1011. doi: 10.1093/biolre/ioae028. Biol Reprod. 2024. PMID: 38408206 Free PMC article.
Early interventions in its expression suggested a regulatory role at the mitotic stages of spermatogenesis, and its early knockout resulted in complete sterility in Drosophila. Genomic and transcriptomic data available for the catadromous giant prawn Macrobrachium rosenber …
Early interventions in its expression suggested a regulatory role at the mitotic stages of spermatogenesis, and its early knockout resulted …
The varying estimation of infertility in Ethiopia: the need for a comprehensive definition.
Araya BM, Aldersey HM, Camara S, Alemu K, Dyer S, Velez MP. Araya BM, et al. BMC Womens Health. 2024 May 8;24(1):280. doi: 10.1186/s12905-024-03118-8. BMC Womens Health. 2024. PMID: 38720297 Free PMC article.
BACKGROUND: Infertility is a marginalized sexual and reproductive health issue in low-resource settings. ...CONCLUSION: The demographic definition of infertility resulted in a lower estimate of infertility. The current duration approach definition coul …
BACKGROUND: Infertility is a marginalized sexual and reproductive health issue in low-resource settings. ...CONCLUSION: The de …
Placental Cannabinoid Receptor Expression in Preterm Birth.
Feduniw S, Krupa I, Łagowska K, Laudański P, Tabarkiewicz J, Stawarz B, Raba G. Feduniw S, et al. J Pregnancy. 2024 May 7;2024:6620156. doi: 10.1155/2024/6620156. eCollection 2024. J Pregnancy. 2024. PMID: 38745869 Free PMC article.
Ovarian response to controlled stimulation and its predictors in a limited-resource setting.
Dermolo M, Ansa M, Siferih M. Dermolo M, et al. BMC Womens Health. 2024 May 7;24(1):279. doi: 10.1186/s12905-024-02991-7. BMC Womens Health. 2024. PMID: 38714986 Free PMC article.
BACKGROUND: Infertility remains a serious health concern for Ethiopian women. Most of its treatment approaches entail controlled ovarian stimulation, the responses of which vary. ...
BACKGROUND: Infertility remains a serious health concern for Ethiopian women. Most of its treatment approaches entail controlled ovar …
Comparison of the pregnancy outcomes of progestin-primed vs. antagonist ovarian stimulation in patients with poor ovarian response: a retrospective study.
Shi Z, Zhao W, Wu X, Bi X. Shi Z, et al. Gynecol Endocrinol. 2024 May 6;40(1):2352133. doi: 10.1080/09513590.2024.2352133. Epub 2024 May 15. Gynecol Endocrinol. 2024. PMID: 38749017 Free article.
METHODS: This retrospective study included patients with POR who underwent COS at the Reproductive Medical Center of Shanxi Maternal and Child Health Hospital from January 2021 to April 2022. ...The cycles were divided into the GnRH-ant (n = 236 cycles) and PPOS (n = 273 c …
METHODS: This retrospective study included patients with POR who underwent COS at the Reproductive Medical Center of Shanxi Maternal …
Gonadotropin elevation is ootoxic to ovulatory oocytes and inhibits oocyte maturation, and activin decoy receptor ActRIIB:Fc therapeutically restores maturation.
Bernstein LR, Mackenzie ACL, Chaffin CL, Lee SJ, Kraemer DC, Merchenthaler I. Bernstein LR, et al. Reprod Biol Endocrinol. 2024 May 6;22(1):52. doi: 10.1186/s12958-024-01224-8. Reprod Biol Endocrinol. 2024. PMID: 38711160 Free PMC article.
BACKGROUND: Elevated FSH often occurs in women of advanced maternal age (AMA, age 35) and in infertility patients undergoing controlled ovarian stimulation (COS). There is controversy on whether high endogenous FSH contributes to infertility and whether high exogeno …
BACKGROUND: Elevated FSH often occurs in women of advanced maternal age (AMA, age 35) and in infertility patients undergoing controll …
A comprehensive analysis of spermatozoal RNA elements in idiopathic infertile males undergoing fertility treatment.
Hamilton M, Russell S, Swanson GM, Krawetz SA, Menezes K, Moskovtsev SI, Librach C. Hamilton M, et al. Sci Rep. 2024 May 5;14(1):10316. doi: 10.1038/s41598-024-60586-6. Sci Rep. 2024. PMID: 38705876 Free PMC article.
Current approaches to diagnosing male infertility inadequately assess the complexity of the male gamete. Beyond the paternal haploid genome, spermatozoa also deliver coding and non-coding RNAs to the oocyte. ...This knowledge can be leveraged to improve clinical screening …
Current approaches to diagnosing male infertility inadequately assess the complexity of the male gamete. Beyond the paternal haploid …
Role of mitochondrial DNA level in epidural-related maternal fever: a single-centre, observational, pilot study.
Hafner C, Windpassinger M, Tretter EV, Rebernig KA, Reindl SM, Hochreiter B, Dekan S, Haider P, Kiss H, Klein KU, Wohlrab P. Hafner C, et al. BMC Pregnancy Childbirth. 2024 May 3;24(1):341. doi: 10.1186/s12884-024-06551-7. BMC Pregnancy Childbirth. 2024. PMID: 38702618 Free PMC article.
Circulating cell-free mitochondrial deoxyribonucleic acid (mtDNA) is one of the possible triggers of sterile inflammatory processes; however, a connection has not been investigated so far. ...Further work is urgently required to understand the connections between the ERMF …
Circulating cell-free mitochondrial deoxyribonucleic acid (mtDNA) is one of the possible triggers of sterile inflammatory processes; …
Resistant ovary syndrome: Two case reports and a literature review of effective controlled ovarian stimulation in IVF.
Zhao S, Zheng W, Gu X, Liang G, Long G. Zhao S, et al. Medicine (Baltimore). 2024 May 3;103(18):e37886. doi: 10.1097/MD.0000000000037886. Medicine (Baltimore). 2024. PMID: 38701292 Free PMC article. Review.
INTRODUCTION: Resistant ovary syndrome (ROS) represents a rare reproductive endocrine disorder that is predominantly associated with infertility, characterized by heightened endogenous gonadotropin levels in the presence of a normal ovarian reserve. ...
INTRODUCTION: Resistant ovary syndrome (ROS) represents a rare reproductive endocrine disorder that is predominantly associated with …
Effects of antisperm antibodies post vasectomy reversal on pregnancy rates.
Abouelgreed TA, Amer MA, Mamdouh H, El-Sherbiny AF, Aboelwafa H, Omar OA, Abdelshakour M, Elesawy M, Sonbol M, Maawad AN, Zayed EM, Eldestawy MT. Abouelgreed TA, et al. Arch Ital Urol Androl. 2024 May 2;96(2):12335. doi: 10.4081/aiua.2024.12335. Arch Ital Urol Androl. 2024. PMID: 38700009 Free article.
Vitamin D and reproductive disorders: a comprehensive review with a focus on endometriosis.
Farhangnia P, Noormohammadi M, Delbandi AA. Farhangnia P, et al. Reprod Health. 2024 May 2;21(1):61. doi: 10.1186/s12978-024-01797-y. Reprod Health. 2024. PMID: 38698459 Free PMC article. Review.
However, data investigating the association between vitamin D levels and reproductive disorders, including endometriosis, have encountered inconsistencies. Therefore, the present study aims to review existing research on the effect of vitamin D on proper reproductive
However, data investigating the association between vitamin D levels and reproductive disorders, including endometriosis, have encoun …
Resumption of ovulation in anovulatory women with PCOS and obesity is associated with reduction of 11β-hydroxyandrostenedione concentrations.
Wang Z, Van Faassen M, Groen H, Cantineau AEP, Van Oers A, Van der Veen A, Hawley JM, Keevil BG, Kema IP, Hoek A. Wang Z, et al. Hum Reprod. 2024 May 2;39(5):1078-1088. doi: 10.1093/humrep/deae058. Hum Reprod. 2024. PMID: 38503490 Free PMC article. Clinical Trial.
However, the mechanisms underlying why some women with PCOS remain anovulatory and others resume ovulation after weight loss are unclear. Reproductive characteristics at baseline and a greater degree of change in endocrine and metabolic features with lifestyle intervention …
However, the mechanisms underlying why some women with PCOS remain anovulatory and others resume ovulation after weight loss are unclear. …
Economic evaluations of assisted reproductive technologies in high-income countries: a systematic review.
Olive E, Bull C, Gordon A, Davies-Tuck M, Wang R, Callander E. Olive E, et al. Hum Reprod. 2024 May 2;39(5):981-991. doi: 10.1093/humrep/deae039. Hum Reprod. 2024. PMID: 38438132 Free PMC article.
STUDY QUESTION: Which assited reproductive technology (ART) interventions in high-income countries are cost-effective and which are not? ...In addition, there is insufficient knowledge of the willingness to pay thresholds of individuals and state funders for treatment of …
STUDY QUESTION: Which assited reproductive technology (ART) interventions in high-income countries are cost-effective and which are n …
Assessing the influence of preconception diet on male fertility: a systematic scoping review.
Tully CA, Alesi S, McPherson NO, Sharkey DJ, Teong XT, Tay CT, Silva TR, Puglisi C, Barsby JP, Moran LJ, Grieger JA, Mousa A. Tully CA, et al. Hum Reprod Update. 2024 May 2;30(3):243-261. doi: 10.1093/humupd/dmad035. Hum Reprod Update. 2024. PMID: 38237150 Free PMC article.
OBJECTIVE AND RATIONALE: The purpose of this scoping review is to examine the extent and range of research undertaken to evaluate the effect(s) of diet in the preconception period on male clinical fertility and reproductive outcomes. SEARCH METHODS: Four electronic databas …
OBJECTIVE AND RATIONALE: The purpose of this scoping review is to examine the extent and range of research undertaken to evaluate the effect …
Pregnancy co-treated with oral gonadotropin-releasing hormone antagonist in a woman with premature ovarian insufficiency: a case report.
Inoue D, Kondo M, Mizuno R, Shibuya S, Hashiba Y, Asada Y. Inoue D, et al. Nagoya J Med Sci. 2024 May;86(2):333-340. doi: 10.18999/nagjms.86.2.333. Nagoya J Med Sci. 2024. PMID: 38962420 Free PMC article.
This case shows the possibility of using an oral GnRH antagonist as an option for infertility treatment....
This case shows the possibility of using an oral GnRH antagonist as an option for infertility treatment....
The effects of conservative and surgical approaches in tubal ectopic pregnancy on fertility.
Dur R, Nalcakan A, Aytekin O, Cirik DA, Yaniktepe B, Gelisen O. Dur R, et al. Ann Saudi Med. 2024 May-Jun;44(3):141-145. doi: 10.5144/0256-4947.2024.141. Epub 2024 Jun 6. Ann Saudi Med. 2024. PMID: 38853473 Free article.
There was no significant difference between the conservative and surgical treatment groups with respect to infertility rate (35.9% vs 41.9%, P=.72) and admittance to the IVF program (3.9% vs 6.8%, P=.39) following ectopic pregnancy treatment. CONCLUSIONS: Reproductive
There was no significant difference between the conservative and surgical treatment groups with respect to infertility rate (35.9% vs …
Prognostic factors for IVF-ICSI live birth rate in women with endometriosis-related infertility.
Tew MP, Rahilah AS, Rosliza S. Tew MP, et al. Med J Malaysia. 2024 May;79(3):288-295. Med J Malaysia. 2024. PMID: 38817061 Free article.
CONCLUSION: A prolonged infertility duration, the presence of adenomyosis, and moderate to severe endometriosis negatively impacted the cumulative LBR in IVF-ICSI treatments for women with endometriosis. Consequently, early aggressive infertility treatments for pati …
CONCLUSION: A prolonged infertility duration, the presence of adenomyosis, and moderate to severe endometriosis negatively impacted t …