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Page 1
Loss of Dnmt3a increases self-renewal and resistance to pegIFN-α in JAK2-V617F-positive myeloproliferative neoplasms.
Usart M, Stetka J, Luque Paz D, Hansen N, Kimmerlin Q, Almeida Fonseca T, Lock M, Kubovcakova L, Karjalainen R, Hao-Shen H, Börsch A, El Taher A, Schulz J, Leroux JC, Dirnhofer S, Skoda RC. Usart M, et al. Among authors: stetka j. Blood. 2024 Jun 13;143(24):2490-2503. doi: 10.1182/blood.2023020270. Blood. 2024. PMID: 38493481 Free PMC article.
Iron is a modifier of the phenotypes of JAK2-mutant myeloproliferative neoplasms.
Stetka J, Usart M, Kubovcakova L, Rai S, Rao TN, Sutter J, Hao-Shen H, Dirnhofer S, Geier F, Bader MS, Passweg JR, Manolova V, Dürrenberger F, Ahmed N, Schroeder T, Ganz T, Nemeth E, Silvestri L, Nai A, Camaschella C, Skoda RC. Stetka J, et al. Blood. 2023 Apr 27;141(17):2127-2140. doi: 10.1182/blood.2022017976. Blood. 2023. PMID: 36758212 Free article.
JAK2-V617F and interferon-α induce megakaryocyte-biased stem cells characterized by decreased long-term functionality.
Rao TN, Hansen N, Stetka J, Luque Paz D, Kalmer M, Hilfiker J, Endele M, Ahmed N, Kubovcakova L, Rybarikova M, Hao-Shen H, Geier F, Beisel C, Dirnhofer S, Schroeder T, Brümmendorf TH, Wolf D, Koschmieder S, Skoda RC. Rao TN, et al. Among authors: stetka j. Blood. 2021 Apr 22;137(16):2139-2151. doi: 10.1182/blood.2020005563. Blood. 2021. PMID: 33667305 Free PMC article.
Low Plasma Citrate Levels and Specific Transcriptional Signatures Associated with Quiescence of CD34+ Progenitors Predict Azacitidine Therapy Failure in MDS/AML Patients.
Koralkova P, Belickova M, Kundrat D, Dostalova Merkerova M, Krejcik Z, Szikszai K, Kaisrlikova M, Vesela J, Vyhlidalova P, Stetka J, Hlavackova A, Suttnar J, Flodr P, Stritesky J, Jonasova A, Cermak J, Divoky V. Koralkova P, et al. Among authors: stetka j. Cancers (Basel). 2021 Apr 30;13(9):2161. doi: 10.3390/cancers13092161. Cancers (Basel). 2021. PMID: 33946220 Free PMC article.