Prevalence of Keratoconus Based on Scheimpflug Corneal Tomography Metrics in a Pediatric Population From a Chicago-Based School Age Vision Clinic

Eye Contact Lens. 2024 Mar 1;50(3):121-125. doi: 10.1097/ICL.0000000000001072. Epub 2024 Feb 7.

Abstract

Purpose: Determine the pediatric prevalence of keratoconus (KC) using Scheimpflug corneal tomography.

Methods: A prospective observational study was done on subjects aged 3 to 18 years at the Princeton Vision Clinic, Chicago, IL. Scheimpflug tomography (Pentacam HR, OCULUS Optikgerate GmbH) scans (Belin/Ambrósio Enhanced Ectasia BAD3) yielded BAD Final D (Final D) and Back Elevation at the Thinnest Point (BETP) measurements. Criteria differentiating non-KC from KC suspects & KC were, Non-KC -Final D <2.00 in both eyes; KC suspect -Final D ≥2.00 and <3.00 in combination with BETP ≥18 μm for myopia and ≥28 μm for hyperopia/mixed astigmatism in at least one eye; and KC -Final D of ≥3.00 with BETP ≥18 μm for myopia or ≥28 μm for hyperopia/mixed astigmatism in at least one eye. Two thousand two hundred and six subjects were recorded, removing duplicate and poor-quality scans leaving 2007 subjects.

Results: Of 2007 subjects, six were classified as KC -prevalence of 1:334, three subjects were KC suspects -prevalence of 1:669, and total prevalence of KC suspects and KC was 1:223.

Conclusion: The prevalence of KC in children is higher than previously reported, emphasizing the importance of sensitive screening for KC at its earliest manifestation as standard in pediatric comprehensive eye examinations.

Publication types

  • Observational Study

MeSH terms

  • Astigmatism*
  • Chicago / epidemiology
  • Child
  • Cornea / diagnostic imaging
  • Corneal Pachymetry
  • Corneal Topography / methods
  • Humans
  • Hyperopia*
  • Keratoconus* / diagnosis
  • Keratoconus* / epidemiology
  • Myopia* / diagnosis
  • Myopia* / epidemiology
  • Prevalence
  • Prospective Studies
  • ROC Curve
  • Tomography