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Xanthohumol and related prenylflavonoids from hops and beer: to your good health!
Stevens JF, Page JE. Stevens JF, et al. Phytochemistry. 2004 May;65(10):1317-30. doi: 10.1016/j.phytochem.2004.04.025. Phytochemistry. 2004. PMID: 15231405 Review.
Identification and in vitro biological activities of hop proanthocyanidins: inhibition of nNOS activity and scavenging of reactive nitrogen species.
Stevens JF, Miranda CL, Wolthers KR, Schimerlik M, Deinzer ML, Buhler DR. Stevens JF, et al. J Agric Food Chem. 2002 Jun 5;50(12):3435-43. doi: 10.1021/jf0116202. J Agric Food Chem. 2002. PMID: 12033808
Inhibition of peroxynitrite-mediated LDL oxidation by prenylated flavonoids: the alpha,beta-unsaturated keto functionality of 2'-hydroxychalcones as a novel antioxidant pharmacophore.
Stevens JF, Miranda CL, Frei B, Buhler DR. Stevens JF, et al. Chem Res Toxicol. 2003 Oct;16(10):1277-86. doi: 10.1021/tx020100d. Chem Res Toxicol. 2003. PMID: 14565769
Xanthohumol, a prenylflavonoid derived from hops induces apoptosis and inhibits NF-kappaB activation in prostate epithelial cells.
Colgate EC, Miranda CL, Stevens JF, Bray TM, Ho E. Colgate EC, et al. Among authors: stevens jf. Cancer Lett. 2007 Feb 8;246(1-2):201-9. doi: 10.1016/j.canlet.2006.02.015. Epub 2006 Mar 24. Cancer Lett. 2007. PMID: 16563612
Hop proanthocyanidins induce apoptosis, protein carbonylation, and cytoskeleton disorganization in human colorectal adenocarcinoma cells via reactive oxygen species.
Chung WG, Miranda CL, Stevens JF, Maier CS. Chung WG, et al. Among authors: stevens jf. Food Chem Toxicol. 2009 Apr;47(4):827-36. doi: 10.1016/j.fct.2009.01.015. Food Chem Toxicol. 2009. PMID: 19271284 Free PMC article.
Covalent interaction of ascorbic acid with natural products.
Kesinger NG, Stevens JF. Kesinger NG, et al. Among authors: stevens jf. Phytochemistry. 2009 Dec;70(17-18):1930-9. doi: 10.1016/j.phytochem.2009.09.028. Epub 2009 Oct 28. Phytochemistry. 2009. PMID: 19875138 Free PMC article.
Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.
Legette L, Ma L, Reed RL, Miranda CL, Christensen JM, Rodriguez-Proteau R, Stevens JF. Legette L, et al. Among authors: stevens jf. Mol Nutr Food Res. 2012 Mar;56(3):466-74. doi: 10.1002/mnfr.201100554. Epub 2011 Dec 7. Mol Nutr Food Res. 2012. PMID: 22147307 Free PMC article.
Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.
Legette LL, Luna AY, Reed RL, Miranda CL, Bobe G, Proteau RR, Stevens JF. Legette LL, et al. Among authors: stevens jf. Phytochemistry. 2013 Jul;91:236-41. doi: 10.1016/j.phytochem.2012.04.018. Epub 2012 May 27. Phytochemistry. 2013. PMID: 22640929
A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.
Kirkwood JS, Legette LL, Miranda CL, Jiang Y, Stevens JF. Kirkwood JS, et al. Among authors: stevens jf. J Biol Chem. 2013 Jun 28;288(26):19000-13. doi: 10.1074/jbc.M112.445452. Epub 2013 May 14. J Biol Chem. 2013. PMID: 23673658 Free PMC article.
Human pharmacokinetics of xanthohumol, an antihyperglycemic flavonoid from hops.
Legette L, Karnpracha C, Reed RL, Choi J, Bobe G, Christensen JM, Rodriguez-Proteau R, Purnell JQ, Stevens JF. Legette L, et al. Among authors: stevens jf. Mol Nutr Food Res. 2014 Feb;58(2):248-55. doi: 10.1002/mnfr.201300333. Epub 2013 Aug 27. Mol Nutr Food Res. 2014. PMID: 24038952 Free PMC article.
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