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PSNCBAM-1 analogs: Structural evolutions and allosteric properties at cannabinoid CB1 receptor.
Meini S, Gado F, Stevenson LA, Digiacomo M, Saba A, Codini S, Macchia M, Pertwee RG, Bertini S, Manera C. Meini S, et al. Among authors: stevenson la. Eur J Med Chem. 2020 Oct 1;203:112606. doi: 10.1016/j.ejmech.2020.112606. Epub 2020 Jul 12. Eur J Med Chem. 2020. PMID: 32682199
Climate change research in Asia: A knowledge synthesis of Asia-Pacific Network for Global Change Research (2013-2018).
Uchiyama C, Stevenson LA, Tandoko E. Uchiyama C, et al. Among authors: stevenson la. Environ Res. 2020 Sep;188:109635. doi: 10.1016/j.envres.2020.109635. Epub 2020 May 6. Environ Res. 2020. PMID: 32526496
Host thermoregulatory constraints predict growth of an amphibian chytrid pathogen (Batrachochytrium dendrobatidis).
Stevenson LA, Roznik EA, Greenspan SE, Alford RA, Pike DA. Stevenson LA, et al. J Therm Biol. 2020 Jan;87:102472. doi: 10.1016/j.jtherbio.2019.102472. Epub 2019 Nov 27. J Therm Biol. 2020. PMID: 31999604
Indomethacin Enhances Type 1 Cannabinoid Receptor Signaling.
Laprairie RB, Mohamed KA, Zagzoog A, Kelly MEM, Stevenson LA, Pertwee R, Denovan-Wright EM, Thakur GA. Laprairie RB, et al. Among authors: stevenson la. Front Mol Neurosci. 2019 Oct 18;12:257. doi: 10.3389/fnmol.2019.00257. eCollection 2019. Front Mol Neurosci. 2019. PMID: 31680861 Free PMC article.
Identification of the First Synthetic Allosteric Modulator of the CB2 Receptors and Evidence of Its Efficacy for Neuropathic Pain Relief.
Gado F, Di Cesare Mannelli L, Lucarini E, Bertini S, Cappelli E, Digiacomo M, Stevenson LA, Macchia M, Tuccinardi T, Ghelardini C, Pertwee RG, Manera C. Gado F, et al. Among authors: stevenson la. J Med Chem. 2019 Jan 10;62(1):276-287. doi: 10.1021/acs.jmedchem.8b00368. Epub 2018 Jul 23. J Med Chem. 2019. PMID: 29990428
Cannabidiolic acid methyl ester, a stable synthetic analogue of cannabidiolic acid, can produce 5-HT1A receptor-mediated suppression of nausea and anxiety in rats.
Pertwee RG, Rock EM, Guenther K, Limebeer CL, Stevenson LA, Haj C, Smoum R, Parker LA, Mechoulam R. Pertwee RG, et al. Among authors: stevenson la. Br J Pharmacol. 2018 Jan;175(1):100-112. doi: 10.1111/bph.14073. Epub 2017 Dec 5. Br J Pharmacol. 2018. PMID: 29057454 Free PMC article.
Big conductance calcium-activated potassium channel openers control spasticity without sedation.
Baker D, Pryce G, Visintin C, Sisay S, Bondarenko AI, Vanessa Ho WS, Jackson SJ, Williams TE, Al-Izki S, Sevastou I, Okuyama M, Graier WF, Stevenson LA, Tanner C, Ross R, Pertwee RG, Henstridge CM, Irving AJ, Schulman J, Powell K, Baker MD, Giovannoni G, Selwood DL. Baker D, et al. Among authors: stevenson la. Br J Pharmacol. 2017 Aug;174(16):2662-2681. doi: 10.1111/bph.13889. Epub 2017 Jul 7. Br J Pharmacol. 2017. PMID: 28677901 Free PMC article. Clinical Trial.
Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor.
Laprairie RB, Kulkarni PM, Deschamps JR, Kelly MEM, Janero DR, Cascio MG, Stevenson LA, Pertwee RG, Kenakin TP, Denovan-Wright EM, Thakur GA. Laprairie RB, et al. Among authors: stevenson la. ACS Chem Neurosci. 2017 Jun 21;8(6):1188-1203. doi: 10.1021/acschemneuro.6b00310. Epub 2017 Feb 7. ACS Chem Neurosci. 2017. PMID: 28103441
Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe.
Laprairie RB, Kulkarni AR, Kulkarni PM, Hurst DP, Lynch D, Reggio PH, Janero DR, Pertwee RG, Stevenson LA, Kelly ME, Denovan-Wright EM, Thakur GA. Laprairie RB, et al. Among authors: stevenson la. ACS Chem Neurosci. 2016 Jun 15;7(6):776-98. doi: 10.1021/acschemneuro.6b00041. Epub 2016 Apr 25. ACS Chem Neurosci. 2016. PMID: 27046127 Free PMC article.
Host-specific thermal profiles affect fitness of a widespread pathogen.
Stevenson LA, Roznik EA, Alford RA, Pike DA. Stevenson LA, et al. Ecol Evol. 2014 Nov;4(21):4053-64. doi: 10.1002/ece3.1271. Epub 2014 Oct 3. Ecol Evol. 2014. PMID: 25505533 Free PMC article.
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