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1997 1
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1999 2
2000 1
2001 3
2002 4
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247 results

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Page 1
Calmodulin-Targeting Molecules from Ageratina grandifolia.
Gutiérrez-González JA, Pérez-Vásquez A, González-Andrade M, Galano A, Villaseñor JL, Mata R. Gutiérrez-González JA, et al. J Nat Prod. 2023 Nov 24;86(11):2562-2570. doi: 10.1021/acs.jnatprod.3c00794. Epub 2023 Oct 31. J Nat Prod. 2023. PMID: 37906816
Four new natural chemical entities, including 2-hydroxy-alpha-truxillic acid (2), (3R,4S)-2,2-dimethyl-3-hydroxy-4-(1-angeloyloxy)-6-acetyl-7-methoxychromane (3), N-tricosanoyltyramine (4), and grandifolamide (5), were isolated along with 11 known compounds (1, 6-15) from the aer …
Four new natural chemical entities, including 2-hydroxy-alpha-truxillic acid (2), (3R,4S)-2,2-dimethyl-3-hydroxy-4-(1-angeloyloxy)-6-acetyl- …
alpha-Glucosidase Inhibitors from Ageratina grandifolia.
Gutiérrez-González JA, Pérez-Vásquez A, Torres-Colín R, Rangel-Grimaldo M, Rebollar-Ramos D, Mata R. Gutiérrez-González JA, et al. J Nat Prod. 2021 May 28;84(5):1573-1578. doi: 10.1021/acs.jnatprod.1c00105. Epub 2021 Apr 15. J Nat Prod. 2021. PMID: 33857371
Fractionation of an aqueous extract from the aerial parts of Ageratina grandifolia yielded a new natural product, namely, 4-hydroxy-3-((S)-1'-angeloyloxy-(R)-2',3'-epoxy-3'-methyl)butylacetophenone (1), along with eight known compounds, including three flavonoids (2-4) and …
Fractionation of an aqueous extract from the aerial parts of Ageratina grandifolia yielded a new natural product, namely, 4-hydroxy-3 …
Chemical constituents from Aphanamixis grandifolia.
Zhang R, He HP, Di YT, Li SL, Zuo GY, Zhang Y, Hao XJ. Zhang R, et al. Fitoterapia. 2014 Jan;92:100-4. doi: 10.1016/j.fitote.2013.10.014. Epub 2013 Nov 2. Fitoterapia. 2014. PMID: 24188860
Four new terpenoids, nemoralisins D-G (1-4), were isolated from the leaves and stems of Aphanamixis grandifolia, along with two known diterpenoids, nemoralisin C and nemoralisin. ...
Four new terpenoids, nemoralisins D-G (1-4), were isolated from the leaves and stems of Aphanamixis grandifolia, along with two known …
Bridging the Gap: Exploring the Preclinical Potential of Pereskia grandifolia in Metabolic-Associated Fatty Liver Disease.
Rodrigues Albuquerque E, Ratti da Silva G, de Abreu Braga F, Pelegrini Silva E, Sposito Negrini K, Rodrigues Fracasso JA, Pires Guarnier L, Jacomassi E, Ribeiro-Paes JT, da Silva Gomes R, Gasparotto Junior A, Lívero FADR. Rodrigues Albuquerque E, et al. Evid Based Complement Alternat Med. 2023 Nov 9;2023:8840427. doi: 10.1155/2023/8840427. eCollection 2023. Evid Based Complement Alternat Med. 2023. PMID: 38026733 Free PMC article.
This research aims to determine the hepatoprotective properties of P. grandifolia using a model of MAFLD. The study was carried out through various phases to assess the safety and efficacy of the ethanol-soluble fraction of P. grandifolia. ...These findings emphasiz …
This research aims to determine the hepatoprotective properties of P. grandifolia using a model of MAFLD. The study was carried out t …
Bisindole alkaloids from Voacanga grandifolia leaves.
Nugroho AE, Ono Y, Jin E, Hirasawa Y, Kaneda T, Rahman A, Kusumawati I, Tougan T, Horii T, Zaini NC, Morita H. Nugroho AE, et al. J Nat Med. 2021 Mar;75(2):408-414. doi: 10.1007/s11418-020-01475-w. Epub 2021 Jan 19. J Nat Med. 2021. PMID: 33462757
Two new bisindole alkaloids, 12'-O-demethyl-vobtusine-5-lactam and isovobtusine-N-oxide (1 and 2), were isolated from the leaves of Voacanga grandifolia, together with two known bisindole alkaloids. Their structures were elucidated on the basis of 1D and 2D NMR data. 1 and …
Two new bisindole alkaloids, 12'-O-demethyl-vobtusine-5-lactam and isovobtusine-N-oxide (1 and 2), were isolated from the leaves of Voacanga …
Antiproliferative Activity of Krukovine by Regulating Transmembrane Protein 139 (TMEM139) in Oxaliplatin-Resistant Pancreatic Cancer Cells.
Lee JH, Lee SH, Lee SK, Choi JH, Lim S, Kim MS, Lee KM, Lee MW, Ku JL, Kim DH, Cho IR, Paik WH, Ryu JK, Kim YT. Lee JH, et al. Cancers (Basel). 2023 May 7;15(9):2642. doi: 10.3390/cancers15092642. Cancers (Basel). 2023. PMID: 37174108 Free PMC article.
Krukovine (KV) is an alkaloid isolated from the bark of Abuta grandifolia (Mart.) Sandw. (Menispermaceae) with anticancer potential in some cancers with KRAS mutations. ...
Krukovine (KV) is an alkaloid isolated from the bark of Abuta grandifolia (Mart.) Sandw. (Menispermaceae) with anticancer potential i …
Chemical constituents from Aphanamixis grandifolia.
Liu Q, Chen CJ, Shi X, Zhang L, Chen HJ, Gao K. Liu Q, et al. Chem Pharm Bull (Tokyo). 2010 Nov;58(11):1431-5. doi: 10.1248/cpb.58.1431. Chem Pharm Bull (Tokyo). 2010. PMID: 21048332 Free article.
(23E)-25-Methylcycloart-23-en-3beta-ol (1), a cycloartane-type triterpenoid featuring an unusual skeleton of 31 carbon atoms, (17E)-cycloart-17,26-dien-3beta-ol (2), a new cycloartane-type triterpenoid, and the other two new compounds 4R-hydroxy-4-(9S-hydroxy-12-methylhexan-6-yl) …
(23E)-25-Methylcycloart-23-en-3beta-ol (1), a cycloartane-type triterpenoid featuring an unusual skeleton of 31 carbon atoms, (17E)-cycloart …
Hepatoprotective diterpenoids from the roots of Salvia grandifolia.
Kang J, Zhang T, Li L, Sun H, Wang DD, Chen RY. Kang J, et al. J Asian Nat Prod Res. 2016 May;18(5):504-8. doi: 10.1080/10286020.2015.1130705. Epub 2016 Apr 18. J Asian Nat Prod Res. 2016. PMID: 27086714
One new diterpenoid, grandifolia G (1), together with a known diterpenoid (6,7,8,8a-tetrahydro-6,6-dimethyl-2-oxonaphtho[1,8-bc]furan-3-yl)-4-methylfuran-3-carboxylic acid (2), was isolated from 70% EtOH extract of root of Salvia grandifolia. ...
One new diterpenoid, grandifolia G (1), together with a known diterpenoid (6,7,8,8a-tetrahydro-6,6-dimethyl-2-oxonaphtho[1,8-bc]furan …
Metabolomic profile, anti-trypanosomal potential and molecular docking studies of Thunbergia grandifolia.
El-Nashar HAS, Sayed AM, El-Sherief HAM, Rateb ME, Akil L, Khadra I, Majrashi TA, Al-Rashood ST, Binjubair FA, El Hassab MA, Eldehna WM, Abdelmohsen UR, Mostafa NM. El-Nashar HAS, et al. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2199950. doi: 10.1080/14756366.2023.2199950. J Enzyme Inhib Med Chem. 2023. PMID: 37080775 Free PMC article.
This study aimed to examine the metabolic profile and anti-trypanosomal effect of methanol extract of Thunbergia grandifolia leaves. The liquid chromatography-high resolution electrospray ionisation mass spectrometry (LC-HRESIMS) revealed the identification of fifteen comp …
This study aimed to examine the metabolic profile and anti-trypanosomal effect of methanol extract of Thunbergia grandifolia leaves. …
247 results