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Human Pancreatic β Cell lncRNAs Control Cell-Specific Regulatory Networks.
Akerman I, Tu Z, Beucher A, Rolando DMY, Sauty-Colace C, Benazra M, Nakic N, Yang J, Wang H, Pasquali L, Moran I, Garcia-Hurtado J, Castro N, Gonzalez-Franco R, Stewart AF, Bonner C, Piemonti L, Berney T, Groop L, Kerr-Conte J, Pattou F, Argmann C, Schadt E, Ravassard P, Ferrer J. Akerman I, et al. Among authors: stewart af. Cell Metab. 2017 Feb 7;25(2):400-411. doi: 10.1016/j.cmet.2016.11.016. Epub 2016 Dec 29. Cell Metab. 2017. PMID: 28041957 Free PMC article.
Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas.
Wang H, Bender A, Wang P, Karakose E, Inabnet WB, Libutti SK, Arnold A, Lambertini L, Stang M, Chen H, Kasai Y, Mahajan M, Kinoshita Y, Fernandez-Ranvier G, Becker TC, Takane KK, Walker LA, Saul S, Chen R, Scott DK, Ferrer J, Antipin Y, Donovan M, Uzilov AV, Reva B, Schadt EE, Losic B, Argmann C, Stewart AF. Wang H, et al. Among authors: stewart af. Nat Commun. 2017 Oct 3;8(1):767. doi: 10.1038/s41467-017-00992-9. Nat Commun. 2017. PMID: 28974674 Free PMC article.
Aberrant methylation underlies insulin gene expression in human insulinoma.
Karakose E, Wang H, Inabnet W, Thakker RV, Libutti S, Fernandez-Ranvier G, Suh H, Stevenson M, Kinoshita Y, Donovan M, Antipin Y, Li Y, Liu X, Jin F, Wang P, Uzilov A, Argmann C, Schadt EE, Stewart AF, Scott DK, Lambertini L. Karakose E, et al. Among authors: stewart af. Nat Commun. 2020 Oct 15;11(1):5210. doi: 10.1038/s41467-020-18839-1. Nat Commun. 2020. PMID: 33060578 Free PMC article.
Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells.
Wang P, Karakose E, Liu H, Swartz E, Ackeifi C, Zlatanic V, Wilson J, González BJ, Bender A, Takane KK, Ye L, Harb G, Pagliuca F, Homann D, Egli D, Argmann C, Scott DK, Garcia-Ocaña A, Stewart AF. Wang P, et al. Among authors: stewart af. Cell Metab. 2019 Mar 5;29(3):638-652.e5. doi: 10.1016/j.cmet.2018.12.005. Epub 2018 Dec 20. Cell Metab. 2019. PMID: 30581122 Free PMC article.
Disrupting the DREAM complex enables proliferation of adult human pancreatic β cells.
Wang P, Karakose E, Argmann C, Wang H, Balev M, Brody RI, Rivas HG, Liu X, Wood O, Liu H, Choleva L, Hasson D, Bernstein E, Paulo JA, Scott DK, Lambertini L, DeCaprio JA, Stewart AF. Wang P, et al. Among authors: stewart af. J Clin Invest. 2022 Aug 1;132(15):e157086. doi: 10.1172/JCI157086. J Clin Invest. 2022. PMID: 35700053 Free PMC article.
Human β-cell proliferation and intracellular signaling: part 3.
Stewart AF, Hussain MA, García-Ocaña A, Vasavada RC, Bhushan A, Bernal-Mizrachi E, Kulkarni RN. Stewart AF, et al. Diabetes. 2015 Jun;64(6):1872-85. doi: 10.2337/db14-1843. Diabetes. 2015. PMID: 25999530 Free PMC article. Review.
Advances in drug discovery for human beta cell regeneration.
Karakose E, Ackeifi C, Wang P, Stewart AF. Karakose E, et al. Among authors: stewart af. Diabetologia. 2018 Aug;61(8):1693-1699. doi: 10.1007/s00125-018-4639-6. Epub 2018 May 16. Diabetologia. 2018. PMID: 29770834 Free PMC article. Review.
600 results