Stick RV - Search Results

1

Iminosugar glycosidase inhibitors: structural and thermodynamic dissection of the binding of isofagomine and 1-deoxynojirimycin to beta-glucosidases.

Zechel DL, Boraston AB, Gloster T, Boraston CM, Macdonald JM, Tilbrook DM, Stick RV, Davies GJ. Zechel DL, et al. Among authors: stick rv. J Am Chem Soc. 2003 Nov 26;125(47):14313-23. doi: 10.1021/ja036833h. J Am Chem Soc. 2003. PMID: 14624580

2

Distortion of a cellobio-derived isofagomine highlights the potential conformational itinerary of inverting beta-glucosidases.

Varrot A, Macdonald J, Stick RV, Pell G, Gilbert HJ, Davies GJ. Varrot A, et al. Among authors: stick rv. Chem Commun (Camb). 2003 Apr 21;(8):946-7. doi: 10.1039/b301592k. Chem Commun (Camb). 2003. PMID: 12744312

3

Direct observation of the protonation state of an imino sugar glycosidase inhibitor upon binding.

Varrot A, Tarling CA, Macdonald JM, Stick RV, Zechel DL, Withers SG, Davies GJ. Varrot A, et al. Among authors: stick rv. J Am Chem Soc. 2003 Jun 25;125(25):7496-7. doi: 10.1021/ja034917k. J Am Chem Soc. 2003. PMID: 12812472

4

Structural, thermodynamic, and kinetic analyses of tetrahydrooxazine-derived inhibitors bound to beta-glucosidases.

Gloster TM, Macdonald JM, Tarling CA, Stick RV, Withers SG, Davies GJ. Gloster TM, et al. Among authors: stick rv. J Biol Chem. 2004 Nov 19;279(47):49236-42. doi: 10.1074/jbc.M407195200. Epub 2004 Sep 8. J Biol Chem. 2004. PMID: 15356002 Free article.

5

Common inhibition of both beta-glucosidases and beta-mannosidases by isofagomine lactam reflects different conformational itineraries for pyranoside hydrolysis.

Vincent F, Gloster TM, Macdonald J, Morland C, Stick RV, Dias FM, Prates JA, Fontes CM, Gilbert HJ, Davies GJ. Vincent F, et al. Among authors: stick rv. Chembiochem. 2004 Nov 5;5(11):1596-9. doi: 10.1002/cbic.200400169. Chembiochem. 2004. PMID: 15515081 No abstract available.

6

Glycosidase inhibition: an assessment of the binding of 18 putative transition-state mimics.

Gloster TM, Meloncelli P, Stick RV, Zechel D, Vasella A, Davies GJ. Gloster TM, et al. Among authors: stick rv. J Am Chem Soc. 2007 Feb 28;129(8):2345-54. doi: 10.1021/ja066961g. Epub 2007 Feb 6. J Am Chem Soc. 2007. PMID: 17279749

7

Mycobacterium tuberculosis strains possess functional cellulases.

Varrot A, Leydier S, Pell G, Macdonald JM, Stick RV, Henrissat B, Gilbert HJ, Davies GJ. Varrot A, et al. Among authors: stick rv. J Biol Chem. 2005 May 27;280(21):20181-4. doi: 10.1074/jbc.C500142200. Epub 2005 Apr 11. J Biol Chem. 2005. PMID: 15824123 Free article.

8

How family 26 glycoside hydrolases orchestrate catalysis on different polysaccharides: structure and activity of a Clostridium thermocellum lichenase, CtLic26A.

Taylor EJ, Goyal A, Guerreiro CI, Prates JA, Money VA, Ferry N, Morland C, Planas A, Macdonald JA, Stick RV, Gilbert HJ, Fontes CM, Davies GJ. Taylor EJ, et al. Among authors: stick rv. J Biol Chem. 2005 Sep 23;280(38):32761-7. doi: 10.1074/jbc.M506580200. Epub 2005 Jun 28. J Biol Chem. 2005. PMID: 15987675 Free article.

9

Substrate distortion by a lichenase highlights the different conformational itineraries harnessed by related glycoside hydrolases.

Money VA, Smith NL, Scaffidi A, Stick RV, Gilbert HJ, Davies GJ. Money VA, et al. Among authors: stick rv. Angew Chem Int Ed Engl. 2006 Aug 4;45(31):5136-40. doi: 10.1002/anie.200600802. Angew Chem Int Ed Engl. 2006. PMID: 16823793 No abstract available.

10

Structural and biochemical evidence for a boat-like transition state in beta-mannosidases.

Tailford LE, Offen WA, Smith NL, Dumon C, Morland C, Gratien J, Heck MP, Stick RV, Blériot Y, Vasella A, Gilbert HJ, Davies GJ. Tailford LE, et al. Among authors: stick rv. Nat Chem Biol. 2008 May;4(5):306-12. doi: 10.1038/nchembio.81. Nat Chem Biol. 2008. PMID: 18408714

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