Stoddard BL - Search Results

1

Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis.

Khare SD, Kipnis Y, Greisen P Jr, Takeuchi R, Ashani Y, Goldsmith M, Song Y, Gallaher JL, Silman I, Leader H, Sussman JL, Stoddard BL, Tawfik DS, Baker D. Khare SD, et al. Among authors: stoddard bl. Nat Chem Biol. 2012 Feb 5;8(3):294-300. doi: 10.1038/nchembio.777. Nat Chem Biol. 2012. PMID: 22306579 Free PMC article.

2

DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI.

Flick KE, Jurica MS, Monnat RJ Jr, Stoddard BL. Flick KE, et al. Among authors: stoddard bl. Nature. 1998 Jul 2;394(6688):96-101. doi: 10.1038/27952. Nature. 1998. PMID: 9665136

3

Design, activity, and structure of a highly specific artificial endonuclease.

Chevalier BS, Kortemme T, Chadsey MS, Baker D, Monnat RJ, Stoddard BL. Chevalier BS, et al. Among authors: stoddard bl. Mol Cell. 2002 Oct;10(4):895-905. doi: 10.1016/s1097-2765(02)00690-1. Mol Cell. 2002. PMID: 12419232 Free article.

4

Design of a novel globular protein fold with atomic-level accuracy.

Kuhlman B, Dantas G, Ireton GC, Varani G, Stoddard BL, Baker D. Kuhlman B, et al. Among authors: stoddard bl. Science. 2003 Nov 21;302(5649):1364-8. doi: 10.1126/science.1089427. Science. 2003. PMID: 14631033

5

Computational redesign of protein-protein interaction specificity.

Kortemme T, Joachimiak LA, Bullock AN, Schuler AD, Stoddard BL, Baker D. Kortemme T, et al. Among authors: stoddard bl. Nat Struct Mol Biol. 2004 Apr;11(4):371-9. doi: 10.1038/nsmb749. Epub 2004 Mar 21. Nat Struct Mol Biol. 2004. PMID: 15034550

6

Computational thermostabilization of an enzyme.

Korkegian A, Black ME, Baker D, Stoddard BL. Korkegian A, et al. Among authors: stoddard bl. Science. 2005 May 6;308(5723):857-60. doi: 10.1126/science.1107387. Science. 2005. PMID: 15879217 Free PMC article.

7

Computational redesign of endonuclease DNA binding and cleavage specificity.

Ashworth J, Havranek JJ, Duarte CM, Sussman D, Monnat RJ Jr, Stoddard BL, Baker D. Ashworth J, et al. Among authors: stoddard bl. Nature. 2006 Jun 1;441(7093):656-9. doi: 10.1038/nature04818. Nature. 2006. PMID: 16738662 Free PMC article.

8

Computational design of a new hydrogen bond network and at least a 300-fold specificity switch at a protein-protein interface.

Joachimiak LA, Kortemme T, Stoddard BL, Baker D. Joachimiak LA, et al. Among authors: stoddard bl. J Mol Biol. 2006 Aug 4;361(1):195-208. doi: 10.1016/j.jmb.2006.05.022. Epub 2006 May 24. J Mol Biol. 2006. PMID: 16831445

9

Mis-translation of a computationally designed protein yields an exceptionally stable homodimer: implications for protein engineering and evolution.

Dantas G, Watters AL, Lunde BM, Eletr ZM, Isern NG, Roseman T, Lipfert J, Doniach S, Tompa M, Kuhlman B, Stoddard BL, Varani G, Baker D. Dantas G, et al. Among authors: stoddard bl. J Mol Biol. 2006 Oct 6;362(5):1004-24. doi: 10.1016/j.jmb.2006.07.092. Epub 2006 Aug 4. J Mol Biol. 2006. PMID: 16949611

10

De novo computational design of retro-aldol enzymes.

Jiang L, Althoff EA, Clemente FR, Doyle L, Röthlisberger D, Zanghellini A, Gallaher JL, Betker JL, Tanaka F, Barbas CF 3rd, Hilvert D, Houk KN, Stoddard BL, Baker D. Jiang L, et al. Among authors: stoddard bl. Science. 2008 Mar 7;319(5868):1387-91. doi: 10.1126/science.1152692. Science. 2008. PMID: 18323453 Free PMC article.

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