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Early-onset type-II diabetes mellitus (MODY4) linked to IPF1.
Stoffers DA, Ferrer J, Clarke WL, Habener JF. Stoffers DA, et al. Nat Genet. 1997 Oct;17(2):138-9. doi: 10.1038/ng1097-138. Nat Genet. 1997. PMID: 9326926 No abstract available.
A newly discovered role of transcription factors involved in pancreas development and the pathogenesis of diabetes mellitus.
Habener JF, Stoffers DA. Habener JF, et al. Among authors: stoffers da. Proc Assoc Am Physicians. 1998 Jan-Feb;110(1):12-21. Proc Assoc Am Physicians. 1998. PMID: 9460079 Review.
Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence.
Stoffers DA, Zinkin NT, Stanojevic V, Clarke WL, Habener JF. Stoffers DA, et al. Nat Genet. 1997 Jan;15(1):106-10. doi: 10.1038/ng0197-106. Nat Genet. 1997. PMID: 8988180
Insulin promoter factor 1 gene is not a major cause of maturity-onset diabetes of the young in French Caucasians.
Chèvre JC, Hani EH, Stoffers DA, Habener JF, Froguel P. Chèvre JC, et al. Among authors: stoffers da. Diabetes. 1998 May;47(5):843-4. doi: 10.2337/diabetes.47.5.843. Diabetes. 1998. PMID: 9588460 Clinical Trial. No abstract available.
Insulin promoter factor-1 gene mutation linked to early-onset type 2 diabetes mellitus directs expression of a dominant negative isoprotein.
Stoffers DA, Stanojevic V, Habener JF. Stoffers DA, et al. J Clin Invest. 1998 Jul 1;102(1):232-41. doi: 10.1172/JCI2242. J Clin Invest. 1998. PMID: 9649577 Free PMC article.
Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus.
Hani EH, Stoffers DA, Chèvre JC, Durand E, Stanojevic V, Dina C, Habener JF, Froguel P. Hani EH, et al. Among authors: stoffers da. J Clin Invest. 1999 Nov;104(9):R41-8. doi: 10.1172/JCI7469. J Clin Invest. 1999. PMID: 10545531 Free PMC article.
Homeodomain protein IDX-1: a master regulator of pancreas development and insulin gene expression.
Stoffers DA, Thomas MK, Habener JF. Stoffers DA, et al. Trends Endocrinol Metab. 1997 May-Jun;8(4):145-51. doi: 10.1016/s1043-2760(97)00008-8. Trends Endocrinol Metab. 1997. PMID: 18406800
Misexpression of the pancreatic homeodomain protein IDX-1 by the Hoxa-4 promoter associated with agenesis of the cecum.
Heller RS, Stoffers DA, Hussain MA, Miller CP, Habener JF. Heller RS, et al. Among authors: stoffers da. Gastroenterology. 1998 Aug;115(2):381-7. doi: 10.1016/s0016-5085(98)70204-5. Gastroenterology. 1998. PMID: 9679043
Improved glucose tolerance and acinar dysmorphogenesis by targeted expression of transcription factor PDX-1 to the exocrine pancreas.
Heller RS, Stoffers DA, Bock T, Svenstrup K, Jensen J, Horn T, Miller CP, Habener JF, Madsen OD, Serup P. Heller RS, et al. Among authors: stoffers da. Diabetes. 2001 Jul;50(7):1553-61. doi: 10.2337/diabetes.50.7.1553. Diabetes. 2001. PMID: 11423476
Impaired insulin secretion and increased insulin sensitivity in familial maturity-onset diabetes of the young 4 (insulin promoter factor 1 gene).
Clocquet AR, Egan JM, Stoffers DA, Muller DC, Wideman L, Chin GA, Clarke WL, Hanks JB, Habener JF, Elahi D. Clocquet AR, et al. Among authors: stoffers da. Diabetes. 2000 Nov;49(11):1856-64. doi: 10.2337/diabetes.49.11.1856. Diabetes. 2000. PMID: 11078452
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