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Neurophysiological basis and clinical applications of the H-reflex as an adjunct for evaluating response to intrathecal baclofen for spasticity.
Stokic DS, Yablon SA. Stokic DS, et al. Acta Neurochir Suppl. 2007;97(Pt 1):231-41. doi: 10.1007/978-3-211-33079-1_32. Acta Neurochir Suppl. 2007. PMID: 17691382 Review.
Implanted programmable pumps that infuse intrathecal baclofen (ITB) markedly enhance the ability of clinicians to manage severe spasticity in appropriately selected patients. ...We therefore recommend using H-reflex as an adjunct to clinical evaluation …
Implanted programmable pumps that infuse intrathecal baclofen (ITB) markedly enhance the ability of clinicians to manage sever …
Effect of concentration and mode of intrathecal baclofen administration on soleus H-reflex in patients with muscle hypertonia.
Stokic DS, Yablon SA. Stokic DS, et al. Clin Neurophysiol. 2012 Nov;123(11):2200-4. doi: 10.1016/j.clinph.2012.04.007. Epub 2012 May 16. Clin Neurophysiol. 2012. PMID: 22595326 Clinical Trial.
OBJECTIVES: Assess spinal reflex excitability after increasing intrathecal baclofen (ITB) flow by manipulation of drug concentration and mode of administration. METHODS: The effect of concentration was assessed by comparing changes in H-reflex ( …
OBJECTIVES: Assess spinal reflex excitability after increasing intrathecal baclofen (ITB) flow by manipulation of drug …
Dose-response relationship between the H-reflex and continuous intrathecal baclofen administration for management of spasticity.
Stokic DS, Yablon SA, Hayes A, Vesovic-Potic V, Olivier J. Stokic DS, et al. Clin Neurophysiol. 2006 Jun;117(6):1283-9. doi: 10.1016/j.clinph.2006.02.018. Epub 2006 Apr 18. Clin Neurophysiol. 2006. PMID: 16621691 Clinical Trial.
OBJECTIVE: To determine the relationship between the H-reflex (H/M ratio) and continuous intrathecal baclofen (CITB) dose after pump implantation for control of spastic hypertonia. ...Different fitting methods were explored to determine which fu …
OBJECTIVE: To determine the relationship between the H-reflex (H/M ratio) and continuous intrathecal baclofen
Neurophysiologic evaluation of spastic hypertonia: implications for management of the patient with the intrathecal baclofen pump.
Yablon SA, Stokic DS. Yablon SA, et al. Among authors: stokic ds. Am J Phys Med Rehabil. 2004 Oct;83(10 Suppl):S10-8. doi: 10.1097/01.phm.0000141126.11008.7d. Am J Phys Med Rehabil. 2004. PMID: 15448573 Review.
We review studies that highlight the potential utility of neurophysiologic techniques, including the H-reflex, F-wave, and flexion withdrawal reflex, in the objective evaluation of response to intrathecal baclofen administration. The accumulated …
We review studies that highlight the potential utility of neurophysiologic techniques, including the H-reflex, F-wave, and fle …
Comparison of clinical and neurophysiologic responses to intrathecal baclofen bolus administration in moderate-to-severe spasticity after acquired brain injury.
Stokic DS, Yablon SA, Hayes A. Stokic DS, et al. Arch Phys Med Rehabil. 2005 Sep;86(9):1801-6. doi: 10.1016/j.apmr.2005.03.027. Arch Phys Med Rehabil. 2005. PMID: 16181946
OBJECTIVES: To compare clinical and neurophysiologic responses to intrathecal baclofen (ITB) bolus injection in subjects with spasticity after acquired brain injury. ...MAIN OUTCOME MEASURES: Lower-extremity Ashworth Scale score at 2, 4, and 6 hours after ITB bolus; …
OBJECTIVES: To compare clinical and neurophysiologic responses to intrathecal baclofen (ITB) bolus injection in subjects with …
Clinical and neurophysiologic assessment of strength and spasticity during intrathecal baclofen titration in incomplete spinal cord injury: single-subject design.
Bowden M, Stokic DS. Bowden M, et al. Among authors: stokic ds. J Spinal Cord Med. 2009;32(2):183-90. doi: 10.1080/10790268.2009.11760770. J Spinal Cord Med. 2009. PMID: 19569466 Free PMC article.
BACKGROUND/OBJECTIVE: Spasticity after spinal cord injury (SCI) is commonly managed with oral and intrathecal baclofen (ITB), with less attention to the effects on voluntary motor control. ...RESULTS: A dose-dependent change in the Ashworth score and lower limb moto …
BACKGROUND/OBJECTIVE: Spasticity after spinal cord injury (SCI) is commonly managed with oral and intrathecal baclofen (ITB), …