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Blocking of platelets or intrinsic coagulation pathway-driven thrombosis does not prevent cerebral infarctions induced by photothrombosis.
Kleinschnitz C, Braeuninger S, Pham M, Austinat M, Nölte I, Renné T, Nieswandt B, Bendszus M, Stoll G. Kleinschnitz C, et al. Stroke. 2008 Apr;39(4):1262-8. doi: 10.1161/STROKEAHA.107.496448. Epub 2008 Feb 21. Stroke. 2008. PMID: 18292385
In vivo imaging of stepwise vessel occlusion in cerebral photothrombosis of mice by 19F MRI.
Weise G, Basse-Lüsebrink TC, Kleinschnitz C, Kampf T, Jakob PM, Stoll G. Weise G, et al. PLoS One. 2011;6(12):e28143. doi: 10.1371/journal.pone.0028143. Epub 2011 Dec 15. PLoS One. 2011. PMID: 22194810 Free PMC article.
Sustained reperfusion after blockade of glycoprotein-receptor-Ib in focal cerebral ischemia: an MRI study at 17.6 Tesla.
Pham M, Helluy X, Kleinschnitz C, Kraft P, Bartsch AJ, Jakob P, Nieswandt B, Bendszus M, Stoll G. Pham M, et al. PLoS One. 2011 Apr 1;6(4):e18386. doi: 10.1371/journal.pone.0018386. PLoS One. 2011. PMID: 21483769 Free PMC article.
RESULTS: Anti-GPIb treatment led to a relative increase of postischemic CBF vs. controls in the cortical territory of the MCA (2 h: 44.2±6.9 ml/100 g/min versus 24 h: 60.5±8.4; p = 0.0012, F((1,18)) = 14.63) after tMCAO. ...
RESULTS: Anti-GPIb treatment led to a relative increase of postischemic CBF vs. controls in the cortical territory of the MCA (2 h: 44.2±6.9 …
Induction of granulocyte colony-stimulating factor mRNA by focal cerebral ischemia and cortical spreading depression.
Kleinschnitz C, Schroeter M, Jander S, Stoll G. Kleinschnitz C, et al. Brain Res Mol Brain Res. 2004 Nov 24;131(1-2):73-8. doi: 10.1016/j.molbrainres.2004.08.011. Brain Res Mol Brain Res. 2004. PMID: 15530654
Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic growth factor with neuroprotective and antiinflammatory properties. ...In conclusion, G-CSF induction in the brain may be part of an intrinsic stress response aimed at limitation of neuronal damage....
Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic growth factor with neuroprotective and antiinflammatory properties. …
Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation.
Kleinschnitz C, Schwab N, Kraft P, Hagedorn I, Dreykluft A, Schwarz T, Austinat M, Nieswandt B, Wiendl H, Stoll G. Kleinschnitz C, et al. Blood. 2010 May 6;115(18):3835-42. doi: 10.1182/blood-2009-10-249078. Epub 2010 Mar 9. Blood. 2010. PMID: 20215643
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