A mutant of Sindbis virus which is able to replicate in cells with reduced CTP makes a replicase/transcriptase with a decreased Km for CTP.
Li ML, Lin YH, Simmonds HA, Stollar V.
Li ML, et al. Among authors: stollar v.
J Virol. 2004 Sep;78(18):9645-51. doi: 10.1128/JVI.78.18.9645-9651.2004.
J Virol. 2004.
PMID: 15331697
Free PMC article.
We reported earlier the isolation and characterization of a Sindbis virus mutant, SV(PZF), that can grow in mosquito cells treated with pyrazofurin (PZF), a compound that interferes with pyrimidine biosynthesis (Y. H. Lin, P. Yadav, R. Ravatn, and V. Stollar, Virolo …
We reported earlier the isolation and characterization of a Sindbis virus mutant, SV(PZF), that can grow in mosquito cells treated with pyra …