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miR-29b and miR-198 overexpression in CD8+ T cells of renal cell carcinoma patients down-modulates JAK3 and MCL-1 leading to immune dysfunction.
Gigante M, Pontrelli P, Herr W, Gigante M, D'Avenia M, Zaza G, Cavalcanti E, Accetturo M, Lucarelli G, Carrieri G, Battaglia M, Storkus WJ, Gesualdo L, Ranieri E. Gigante M, et al. Among authors: storkus wj. J Transl Med. 2016 Apr 11;14:84. doi: 10.1186/s12967-016-0841-9. J Transl Med. 2016. PMID: 27063186 Free PMC article.
IL-12p70 and IL-18 gene-modified dendritic cells loaded with tumor antigen-derived peptides or recombinant protein effectively stimulate specific Type-1 CD4+ T-cell responses from normal donors and melanoma patients in vitro.
Vujanovic L, Ranieri E, Gambotto A, Olson WC, Kirkwood JM, Storkus WJ. Vujanovic L, et al. Among authors: storkus wj. Cancer Gene Ther. 2006 Aug;13(8):798-805. doi: 10.1038/sj.cgt.7700964. Epub 2006 Apr 28. Cancer Gene Ther. 2006. PMID: 16645618
228 results