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The interplay of functional tuning, drug resistance, and thermodynamic stability in the evolution of the M2 proton channel from the influenza A virus.
Structure. 2008 Jul;16(7):1067-76. doi: 10.1016/j.str.2008.04.011.
Structure. 2008.
PMID: 18611380
Free PMC article.
Sequence determinants of a transmembrane proton channel: an inverse relationship between stability and function.
Stouffer AL, Nanda V, Lear JD, DeGrado WF.
Stouffer AL, et al.
J Mol Biol. 2005 Mar 18;347(1):169-79. doi: 10.1016/j.jmb.2005.01.023. Epub 2005 Jan 21.
J Mol Biol. 2005.
PMID: 15733926
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Structural basis for the function and inhibition of an influenza virus proton channel.
Stouffer AL, Acharya R, Salom D, Levine AS, Di Costanzo L, Soto CS, Tereshko V, Nanda V, Stayrook S, DeGrado WF.
Stouffer AL, et al.
Nature. 2008 Jan 31;451(7178):596-9. doi: 10.1038/nature06528.
Nature. 2008.
PMID: 18235504
Free PMC article.
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Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel.
Ma C, Polishchuk AL, Ohigashi Y, Stouffer AL, Schön A, Magavern E, Jing X, Lear JD, Freire E, Lamb RA, DeGrado WF, Pinto LH.
Ma C, et al. Among authors: stouffer al.
Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12283-8. doi: 10.1073/pnas.0905726106. Epub 2009 Jul 9.
Proc Natl Acad Sci U S A. 2009.
PMID: 19590009
Free PMC article.
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Association of a model transmembrane peptide containing gly in a heptad sequence motif.
Lear JD, Stouffer AL, Gratkowski H, Nanda V, Degrado WF.
Lear JD, et al. Among authors: stouffer al.
Biophys J. 2004 Nov;87(5):3421-9. doi: 10.1529/biophysj.103.032839. Epub 2004 Aug 17.
Biophys J. 2004.
PMID: 15315956
Free PMC article.
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