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SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis.
Anderson DD, Stover PJ. Anderson DD, et al. Among authors: stover pj. PLoS One. 2009 Jun 9;4(6):e5839. doi: 10.1371/journal.pone.0005839. PLoS One. 2009. PMID: 19513116 Free PMC article.
Arsenic trioxide targets MTHFD1 and SUMO-dependent nuclear de novo thymidylate biosynthesis.
Kamynina E, Lachenauer ER, DiRisio AC, Liebenthal RP, Field MS, Stover PJ. Kamynina E, et al. Among authors: stover pj. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2319-E2326. doi: 10.1073/pnas.1619745114. Epub 2017 Mar 6. Proc Natl Acad Sci U S A. 2017. PMID: 28265077 Free PMC article.
Targeting nuclear thymidylate biosynthesis.
Chon J, Stover PJ, Field MS. Chon J, et al. Among authors: stover pj. Mol Aspects Med. 2017 Feb;53:48-56. doi: 10.1016/j.mam.2016.11.005. Epub 2016 Nov 19. Mol Aspects Med. 2017. PMID: 27876557 Free PMC article. Review.
Human mutations in methylenetetrahydrofolate dehydrogenase 1 impair nuclear de novo thymidylate biosynthesis.
Field MS, Kamynina E, Watkins D, Rosenblatt DS, Stover PJ. Field MS, et al. Among authors: stover pj. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):400-5. doi: 10.1073/pnas.1414555112. Epub 2014 Dec 29. Proc Natl Acad Sci U S A. 2015. PMID: 25548164 Free PMC article.
Competition between sumoylation and ubiquitination of serine hydroxymethyltransferase 1 determines its nuclear localization and its accumulation in the nucleus.
Anderson DD, Eom JY, Stover PJ. Anderson DD, et al. Among authors: stover pj. J Biol Chem. 2012 Feb 10;287(7):4790-9. doi: 10.1074/jbc.M111.302174. Epub 2011 Dec 21. J Biol Chem. 2012. PMID: 22194612 Free PMC article.
Serine hydroxymethyltransferase anchors de novo thymidylate synthesis pathway to nuclear lamina for DNA synthesis.
Anderson DD, Woeller CF, Chiang EP, Shane B, Stover PJ. Anderson DD, et al. Among authors: stover pj. J Biol Chem. 2012 Mar 2;287(10):7051-62. doi: 10.1074/jbc.M111.333120. Epub 2012 Jan 10. J Biol Chem. 2012. PMID: 22235121 Free PMC article.
A hybrid stochastic model of folate-mediated one-carbon metabolism: Effect of the common C677T MTHFR variant on de novo thymidylate biosynthesis.
Misselbeck K, Marchetti L, Field MS, Scotti M, Priami C, Stover PJ. Misselbeck K, et al. Among authors: stover pj. Sci Rep. 2017 Apr 11;7(1):797. doi: 10.1038/s41598-017-00854-w. Sci Rep. 2017. PMID: 28400561 Free PMC article.
MTHFD1 regulates nuclear de novo thymidylate biosynthesis and genome stability.
Field MS, Kamynina E, Stover PJ. Field MS, et al. Among authors: stover pj. Biochimie. 2016 Jul;126:27-30. doi: 10.1016/j.biochi.2016.02.001. Epub 2016 Feb 4. Biochimie. 2016. PMID: 26853819 Free PMC article.
Dietary Uridine Decreases Tumorigenesis in the ApcMin/+ Model of Intestinal Cancer.
Field MS, Lan X, Stover DM, Stover PJ. Field MS, et al. Among authors: stover dm, stover pj. Curr Dev Nutr. 2018 Mar 13;2(5):nzy013. doi: 10.1093/cdn/nzy013. eCollection 2018 May. Curr Dev Nutr. 2018. PMID: 29955725 Free PMC article.
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