Dihydropyrrole-3-thiones: one-pot synthesis from propargylamines, acyl chlorides and sodium sulfide.
Volkov PA, Khrapova KO, Vyi EM, Telezhkin AA, Bidusenko IA, Albanov AI, Schmidt EY, Trofimov BA.
Volkov PA, et al.
Org Biomol Chem. 2023 Aug 30;21(34):6903-6913. doi: 10.1039/d3ob01061a.
Org Biomol Chem. 2023.
PMID: 37581533
An efficient one-pot synthesis of 1,2,5-trisubstituted-1,2-dihydro-3H-pyrrole-3-thiones (up to 91% yield), representatives of essentially new heterocyclic systems, by the successive treatment of available propargylamines with acyl chlorides (PdCl(2)/CuI/Ph(3)P/Et(3)N, tolu …
An efficient one-pot synthesis of 1,2,5-trisubstituted-1,2-dihydro-3H-pyrrole-3-thiones (up to 91% yield), representatives of essentially ne …