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FemA, a host-mediated factor essential for methicillin resistance in Staphylococcus aureus: molecular cloning and characterization.
Berger-Bächi B, Barberis-Maino L, Strässle A, Kayser FH. Berger-Bächi B, et al. Among authors: strassle a. Mol Gen Genet. 1989 Oct;219(1-2):263-9. doi: 10.1007/BF00261186. Mol Gen Genet. 1989. PMID: 2559314
We cloned and characterized a chromosomally determined gene which encodes a factor essential for the expression of methicillin resistance (femA) in S. aureus. femA mapped in chromosomal segment number 18, genetically very distant from the methicillin resistance dete …
We cloned and characterized a chromosomally determined gene which encodes a factor essential for the expression of methicillin …
In vitro activity of oral cephalosporin BAY v 3522 compared with other oral cephalosporins.
Locher R, Strässle A, Kayser FH. Locher R, et al. Among authors: strassle a. Drugs Exp Clin Res. 1990;16(10):515-25. Drugs Exp Clin Res. 1990. PMID: 2100734
MICs ranged from 0.01 mg/l against group A streptococci to 16 mg/l against S. faecium. Although mean MICs of BAY against methicillin-resistant S. aureus and S. epidermidis were between 0.9-1.8 mg/l, respectively, such strains showed typical heteroresistance in population s …
MICs ranged from 0.01 mg/l against group A streptococci to 16 mg/l against S. faecium. Although mean MICs of BAY against methicillin- …
Evidence of a novel staphylococcal mec-encoded element (mecR) controlling expression of penicillin-binding protein 2'.
Tesch W, Ryffel C, Strässle A, Kayser FH, Berger-Bächi B. Tesch W, et al. Among authors: strassle a. Antimicrob Agents Chemother. 1990 Sep;34(9):1703-6. doi: 10.1128/aac.34.9.1703. Antimicrob Agents Chemother. 1990. PMID: 2285282 Free PMC article.
A region was identified on the methicillin resistance determinant (mec) isolated from Staphylococcus epidermidis and cloned into Staphylococcus carnosus which was responsible for a novel downregulation of the expression of methicillin resistance. ...
A region was identified on the methicillin resistance determinant (mec) isolated from Staphylococcus epidermidis and cloned into Stap
Mechanisms of heteroresistance in methicillin-resistant Staphylococcus aureus.
Ryffel C, Strässle A, Kayser FH, Berger-Bächi B. Ryffel C, et al. Among authors: strassle a. Antimicrob Agents Chemother. 1994 Apr;38(4):724-8. doi: 10.1128/aac.38.4.724. Antimicrob Agents Chemother. 1994. PMID: 8031036 Free PMC article.
The femC locus of Staphylococcus aureus required for methicillin resistance includes the glutamine synthetase operon.
Gustafson J, Strässle A, Hächler H, Kayser FH, Berger-Bächi B. Gustafson J, et al. Among authors: strassle a. J Bacteriol. 1994 Mar;176(5):1460-7. doi: 10.1128/jb.176.5.1460-1467.1994. J Bacteriol. 1994. PMID: 7509336 Free PMC article.
Characterization of an isogenic set of methicillin-resistant and susceptible mutants of Staphylococcus aureus.
Berger-Bächi B, Strässle A, Kayser FH. Berger-Bächi B, et al. Among authors: strassle a. Eur J Clin Microbiol. 1986 Dec;5(6):697-701. doi: 10.1007/BF02013308. Eur J Clin Microbiol. 1986. PMID: 3026801
A low affinity penicillin binding protein (PBP2') present in methicillin resistant strains but absent in isogenic sensitive strains of Staphylococcus aureus is responsible for the phenotypic expression of the methicillin resistance. ...Isogenic methicillin sensitive and re
A low affinity penicillin binding protein (PBP2') present in methicillin resistant strains but absent in isogenic sensitive strains o
Cloning and expression of methicillin resistance from Staphylococcus epidermidis in Staphylococcus carnosus.
Tesch W, Strässle A, Berger-Bächi B, O'Hara D, Reynolds P, Kayser FH. Tesch W, et al. Among authors: strassle a. Antimicrob Agents Chemother. 1988 Oct;32(10):1494-9. doi: 10.1128/aac.32.10.1494. Antimicrob Agents Chemother. 1988. PMID: 2903715 Free PMC article.
A 6.2-kilobase chromosomal DNA fragment from a methicillin-resistant Staphylococcus epidermidis strain was cloned into Staphylococcus carnosus by using staphylococcal plasmid pCA44 as the vector. ...These findings point to a common origin of the methicillin r
A 6.2-kilobase chromosomal DNA fragment from a methicillin-resistant Staphylococcus epidermidis strain was cloned into Staphyl
Activity of meropenem, against gram-positive bacteria.
Kayser FH, Morenzoni G, Strässle A, Hadorn K. Kayser FH, et al. Among authors: strassle a. J Antimicrob Chemother. 1989 Sep;24 Suppl A:101-12. doi: 10.1093/jac/24.suppl_a.101. J Antimicrob Chemother. 1989. PMID: 2808202
A new carbapenem antibiotic, meropenem, was shown to be active against a large number of Gram-positive bacteria. The drug inhibited penicillinase-positive and -negative, methicillin-susceptible staphylococci equally well. ...Strains of Ent. faecium, C. jeikeium, and
A new carbapenem antibiotic, meropenem, was shown to be active against a large number of Gram-positive bacteria. The drug inhi
Autolysis of methicillin-resistant and -susceptible Staphylococcus aureus.
Gustafson JE, Berger-Bächi B, Strässle A, Wilkinson BJ. Gustafson JE, et al. Among authors: strassle a. Antimicrob Agents Chemother. 1992 Mar;36(3):566-72. doi: 10.1128/aac.36.3.566. Antimicrob Agents Chemother. 1992. PMID: 1320363 Free PMC article.
Faster rates of autolysis were noted in two heterogeneous methicillin-resistant transductants than in their methicillin-susceptible parental recipients, in a heterogeneous resistant strain than in a susceptible derivative created by chemical mutagenesis, and in a
Faster rates of autolysis were noted in two heterogeneous methicillin-resistant transductants than in their methicillin-susceptible parental …
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