Strömberg K - Search Results

1

Aph-1 interacts at the cell surface with proteins in the active gamma-secretase complex and membrane-tethered Notch.

Hansson EM, Strömberg K, Bergstedt S, Yu G, Näslund J, Lundkvist J, Lendahl U. Hansson EM, et al. Among authors: stromberg k. J Neurochem. 2005 Mar;92(5):1010-20. doi: 10.1111/j.1471-4159.2004.02926.x. J Neurochem. 2005. PMID: 15715652 Free article.

2

gamma-Secretase complexes containing N- and C-terminal fragments of different presenilin origin retain normal gamma-secretase activity.

Strömberg K, Hansson EM, Laudon H, Bergstedt S, Näslund J, Lundkvist J, Lendahl U. Strömberg K, et al. J Neurochem. 2005 Nov;95(3):880-90. doi: 10.1111/j.1471-4159.2005.03415.x. Epub 2005 Aug 31. J Neurochem. 2005. PMID: 16135086 Free article.

3

First and second generation γ-secretase modulators (GSMs) modulate amyloid-β (Aβ) peptide production through different mechanisms.

Borgegard T, Juréus A, Olsson F, Rosqvist S, Sabirsh A, Rotticci D, Paulsen K, Klintenberg R, Yan H, Waldman M, Stromberg K, Nord J, Johansson J, Regner A, Parpal S, Malinowsky D, Radesater AC, Li T, Singh R, Eriksson H, Lundkvist J. Borgegard T, et al. Among authors: stromberg k. J Biol Chem. 2012 Apr 6;287(15):11810-9. doi: 10.1074/jbc.M111.305227. Epub 2012 Feb 13. J Biol Chem. 2012. PMID: 22334705 Free PMC article.

4

Second generation γ-secretase modulators exhibit different modulation of Notch β and Aβ production.

Wanngren J, Ottervald J, Parpal S, Portelius E, Strömberg K, Borgegård T, Klintenberg R, Juréus A, Blomqvist J, Blennow K, Zetterberg H, Lundkvist J, Rosqvist S, Karlström H. Wanngren J, et al. Among authors: stromberg k. J Biol Chem. 2012 Sep 21;287(39):32640-50. doi: 10.1074/jbc.M112.376541. Epub 2012 Jul 31. J Biol Chem. 2012. PMID: 22851182 Free PMC article.

5

Combining an amyloid-beta (Aβ) cleaving enzyme inhibitor with a γ-secretase modulator results in an additive reduction of Aβ production.

Strömberg K, Eketjäll S, Georgievska B, Tunblad K, Eliason K, Olsson F, Radesäter AC, Klintenberg R, Arvidsson PI, von Berg S, Fälting J, Cowburn RF, Dabrowski M. Strömberg K, et al. FEBS J. 2015 Jan;282(1):65-73. doi: 10.1111/febs.13103. Epub 2014 Nov 7. FEBS J. 2015. PMID: 25303711 Free article.

6

Characterization of the effect of a novel γ-secretase modulator on Aβ: a clinically translatable model.

Portelius E, Appelkvist P, Stromberg K, Hoglund K. Portelius E, et al. Among authors: stromberg k. Curr Pharm Des. 2014;20(15):2484-90. doi: 10.2174/13816128113199990499. Curr Pharm Des. 2014. PMID: 23859556

7

Tau-tubulin kinase 1 expression, phosphorylation and co-localization with phospho-Ser422 tau in the Alzheimer's disease brain.

Lund H, Cowburn RF, Gustafsson E, Strömberg K, Svensson A, Dahllund L, Malinowsky D, Sunnemark D. Lund H, et al. Among authors: stromberg k. Brain Pathol. 2013 Jul;23(4):378-89. doi: 10.1111/bpa.12001. Epub 2012 Nov 20. Brain Pathol. 2013. PMID: 23088643 Free PMC article.

8

Imatinib treatment and Aβ42 in humans.

Olsson B, Legros L, Guilhot F, Strömberg K, Smith J, Livesey FJ, Wilson DH, Zetterberg H, Blennow K. Olsson B, et al. Among authors: stromberg k. Alzheimers Dement. 2014 Oct;10(5 Suppl):S374-80. doi: 10.1016/j.jalz.2013.08.283. Epub 2013 Dec 10. Alzheimers Dement. 2014. PMID: 24331439

9

New aminoimidazoles as β-secretase (BACE-1) inhibitors showing amyloid-β (Aβ) lowering in brain.

Gravenfors Y, Viklund J, Blid J, Ginman T, Karlström S, Kihlström J, Kolmodin K, Lindström J, von Berg S, von Kieseritzky F, Bogar K, Slivo C, Swahn BM, Olsson LL, Johansson P, Eketjäll S, Fälting J, Jeppsson F, Strömberg K, Janson J, Rahm F. Gravenfors Y, et al. Among authors: stromberg k. J Med Chem. 2012 Nov 8;55(21):9297-311. doi: 10.1021/jm300991n. Epub 2012 Oct 3. J Med Chem. 2012. PMID: 23017051

10

Genomic organization, sequence analysis, and chromosomal localization of the human carboxyl ester lipase (CEL) gene and a CEL-like (CELL) gene.

Lidberg U, Nilsson J, Strömberg K, Stenman G, Sahlin P, Enerbäck S, Bjursell G. Lidberg U, et al. Among authors: stromberg k. Genomics. 1992 Jul;13(3):630-40. doi: 10.1016/0888-7543(92)90134-e. Genomics. 1992. PMID: 1639390

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