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Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor.
Straus DB, Weiss A. Straus DB, et al. Cell. 1992 Aug 21;70(4):585-93. doi: 10.1016/0092-8674(92)90428-f. Cell. 1992. PMID: 1505025
Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function.
Kong G, Dalton M, Bubeck Wardenburg J, Straus D, Kurosaki T, Chan AC. Kong G, et al. Mol Cell Biol. 1996 Sep;16(9):5026-35. doi: 10.1128/mcb.16.9.5026. Mol Cell Biol. 1996. PMID: 8756661 Free PMC article.
Signal transduction events leading to T-cell lymphokine gene expression.
Fraser JD, Straus D, Weiss A. Fraser JD, et al. Immunol Today. 1993 Jul;14(7):357-62. doi: 10.1016/0167-5699(93)90236-E. Immunol Today. 1993. PMID: 8363726 Review.
Molecular and genetic insights into T cell antigen receptor signal transduction.
Weiss A, Iwashima M, Irving B, van Oers NS, Kadlecek TA, Straus D, Chan A. Weiss A, et al. Adv Exp Med Biol. 1994;365:53-62. doi: 10.1007/978-1-4899-0987-9_6. Adv Exp Med Biol. 1994. PMID: 7887313 No abstract available.
Regulation of protein tyrosine kinase activation by the T-cell antigen receptor zeta chain.
Weiss A, Chan AC, Iwashima M, Straus D, Irving BA. Weiss A, et al. Cold Spring Harb Symp Quant Biol. 1992;57:107-16. doi: 10.1101/sqb.1992.057.01.014. Cold Spring Harb Symp Quant Biol. 1992. PMID: 1339649 No abstract available.
Molecular basis of T cell inactivation by CTLA-4.
Lee KM, Chuang E, Griffin M, Khattri R, Hong DK, Zhang W, Straus D, Samelson LE, Thompson CB, Bluestone JA. Lee KM, et al. Science. 1998 Dec 18;282(5397):2263-6. doi: 10.1126/science.282.5397.2263. Science. 1998. PMID: 9856951
Genetic evidence of a role for Lck in T-cell receptor function independent or downstream of ZAP-70/Syk protein tyrosine kinases.
Wong J, Straus D, Chan AC. Wong J, et al. Mol Cell Biol. 1998 May;18(5):2855-66. doi: 10.1128/mcb.18.5.2855. Mol Cell Biol. 1998. PMID: 9566904 Free PMC article.
Lck SH3 domain function is required for T-cell receptor signals regulating thymocyte development.
Rudd ML, Tua-Smith A, Straus DB. Rudd ML, et al. Among authors: straus db. Mol Cell Biol. 2006 Nov;26(21):7892-900. doi: 10.1128/MCB.00968-06. Epub 2006 Aug 21. Mol Cell Biol. 2006. PMID: 16923964 Free PMC article.
CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1.
Carey KD, Dillon TJ, Schmitt JM, Baird AM, Holdorf AD, Straus DB, Shaw AS, Stork PJ. Carey KD, et al. Among authors: straus db. Mol Cell Biol. 2000 Nov;20(22):8409-19. doi: 10.1128/mcb.20.22.8409-8419.2000. Mol Cell Biol. 2000. PMID: 11046138 Free PMC article.
Superantigen-induced T cell:B cell conjugation is mediated by LFA-1 and requires signaling through Lck, but not ZAP-70.
Morgan MM, Labno CM, Van Seventer GA, Denny MF, Straus DB, Burkhardt JK. Morgan MM, et al. Among authors: straus db. J Immunol. 2001 Nov 15;167(10):5708-18. doi: 10.4049/jimmunol.167.10.5708. J Immunol. 2001. PMID: 11698443
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