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Page 1
Potential Utility of Cannabidiol in Stress-Related Disorders.
Lookfong NA, Raup-Konsavage WM, Silberman Y. Lookfong NA, et al. Cannabis Cannabinoid Res. 2023 Apr;8(2):230-240. doi: 10.1089/can.2022.0130. Epub 2022 Nov 21. Cannabis Cannabinoid Res. 2023. PMID: 36409719 Free PMC article. Review.
However, caution may be warranted in utilization of medicinal cannabinoid products that contain delta-9-tetrahydrocannabinol due to pronounced euphorigenic effects and potential to exacerbate stress-related behaviors. Other cannabinoid products, such as cannabidiol
However, caution may be warranted in utilization of medicinal cannabinoid products that contain delta-9-tetrahydrocannabinol due to pronounc …
Therapeutic potential of cannabidiol (CBD) in anxiety disorders: A systematic review and meta-analysis.
Han K, Wang JY, Wang PY, Peng YC. Han K, et al. Psychiatry Res. 2024 Sep;339:116049. doi: 10.1016/j.psychres.2024.116049. Epub 2024 Jun 21. Psychiatry Res. 2024. PMID: 38924898 Free article.
Cannabidiol (CBD), as one of the phytocannabinoids, has a wide range of therapeutic properties for various neuropsychiatric disorders due to central nervous system effects. ...In addition, this meta-analysis focuses on the efficacy of CBD in treating anxiety disorders such
Cannabidiol (CBD), as one of the phytocannabinoids, has a wide range of therapeutic properties for various neuropsychiatric disorders
Cannabidiol as a Potential Treatment for Anxiety Disorders.
Blessing EM, Steenkamp MM, Manzanares J, Marmar CR. Blessing EM, et al. Neurotherapeutics. 2015 Oct;12(4):825-36. doi: 10.1007/s13311-015-0387-1. Neurotherapeutics. 2015. PMID: 26341731 Free PMC article. Review.
Cannabidiol (CBD), a Cannabis sativa constituent, is a pharmacologically broad-spectrum drug that in recent years has drawn increasing interest as a treatment for a range of neuropsychiatric disorders. ...We found that existing preclinical evidence strongly supports CBD as
Cannabidiol (CBD), a Cannabis sativa constituent, is a pharmacologically broad-spectrum drug that in recent years has drawn increasin
Constituents of Cannabis Sativa.
Rock EM, Parker LA. Rock EM, et al. Adv Exp Med Biol. 2021;1264:1-13. doi: 10.1007/978-3-030-57369-0_1. Adv Exp Med Biol. 2021. PMID: 33332000 Review.
There are more than 550 chemical compounds in cannabis, with more than 100 phytocannabinoids being identified, including delta(9)-tetrahydrocannabinol (THC) and cannabidiol (CBD). These phytocannabinoids work by binding to the cannabinoid receptors, as well as other recept …
There are more than 550 chemical compounds in cannabis, with more than 100 phytocannabinoids being identified, including delta(9)-tetrahydro …
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
Huang T, Xu T, Wang Y, Zhou Y, Yu D, Wang Z, He L, Chen Z, Zhang Y, Davidson D, Dai Y, Hang C, Liu X, Yan C. Huang T, et al. Autophagy. 2021 Nov;17(11):3592-3606. doi: 10.1080/15548627.2021.1885203. Epub 2021 Feb 25. Autophagy. 2021. PMID: 33629929 Free PMC article.
The non-psychoactive phytocannabinoid cannabidiol (CBD) has been shown to be effective against glioma; however, the molecular target and mechanism of action of CBD in glioma are poorly understood. ...Transcriptome analysis and other results demonstrated that ER stress
The non-psychoactive phytocannabinoid cannabidiol (CBD) has been shown to be effective against glioma; however, the molecular target …
Amygdala-hippocampal innervation modulates stress-induced depressive-like behaviors through AMPA receptors.
Ma H, Li C, Wang J, Zhang X, Li M, Zhang R, Huang Z, Zhang Y. Ma H, et al. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2019409118. doi: 10.1073/pnas.2019409118. Proc Natl Acad Sci U S A. 2021. PMID: 33526688 Free PMC article.
Chronic stress is one of the most critical factors in the onset of depressive disorders; hence, environmental factors such as psychosocial stress are commonly used to induce depressive-like traits in animal models of depression. ...Here we employed chronic unpredict …
Chronic stress is one of the most critical factors in the onset of depressive disorders; hence, environmental factors such as psychos …
The NLRP3 Inflammasome in Stress Response: Another Target for the Promiscuous Cannabidiol.
Hartmann A, Vila-Verde C, Guimarães FS, Joca SR, Lisboa SF. Hartmann A, et al. Curr Neuropharmacol. 2023;21(2):284-308. doi: 10.2174/1570159X20666220411101217. Curr Neuropharmacol. 2023. PMID: 35410608 Free PMC article. Review.
The mechanisms are still unclear, but one pathway in microglia has received increased attention in the last 8 years, i.e., the NLRP3 inflammasome pathway. Stress response and inflammation, including microglia activation, can be attenuated by Cannabidiol (CBD). ...Th …
The mechanisms are still unclear, but one pathway in microglia has received increased attention in the last 8 years, i.e., the NLRP3 inflamm …
Cannabidiol protects C2C12 myotubes against cisplatin-induced atrophy by regulating oxidative stress.
Le Bacquer O, Sanchez P, Patrac V, Rivoirard C, Saroul N, Giraudet C, Kocer A, Walrand S. Le Bacquer O, et al. Am J Physiol Cell Physiol. 2024 Apr 1;326(4):C1226-C1236. doi: 10.1152/ajpcell.00622.2023. Epub 2024 Feb 26. Am J Physiol Cell Physiol. 2024. PMID: 38406827 Free article.
The aim of the present study was to investigate whether cannabidiol (CBD) administration may potentially antagonize the effects of cisplatin in inducing muscle atrophy, using a model of myotubes in culture. ...Altogether, our results demonstrated that CBD antagonize the ci …
The aim of the present study was to investigate whether cannabidiol (CBD) administration may potentially antagonize the effects of ci …
Cannabidiol Protects Striatal Neurons by Attenuating Endoplasmic Reticulum Stress.
Patel V, Abu-Hijleh F, Rigg N, Mishra R. Patel V, et al. Cannabis Cannabinoid Res. 2023 Apr;8(2):299-308. doi: 10.1089/can.2022.0090. Epub 2022 Nov 28. Cannabis Cannabinoid Res. 2023. PMID: 36454179
This aggregation leads to the persistent activation of the unfolded protein response (UPR) and ultimately apoptosis as a result of ER stress. Cannabidiol (CBD) has been demonstrated to be neuroprotective in various cellular and animal models of neurodegeneration, wh …
This aggregation leads to the persistent activation of the unfolded protein response (UPR) and ultimately apoptosis as a result of ER str
Cannabidiol attenuates pulmonary arterial hypertension by improving vascular smooth muscle cells mitochondrial function.
Lu X, Zhang J, Liu H, Ma W, Yu L, Tan X, Wang S, Ren F, Li X, Li X. Lu X, et al. Theranostics. 2021 Mar 11;11(11):5267-5278. doi: 10.7150/thno.55571. eCollection 2021. Theranostics. 2021. PMID: 33859746 Free PMC article.
Additionally, CBD's roles in mitochondrial function and oxidant stress were also assessed in PASMCs. Results: We found that CBD reversed the pathological changes observed in both Sugen-hypoxia and monocrotaline-induced PAH rodent models in a cannabinoid receptors-independe …
Additionally, CBD's roles in mitochondrial function and oxidant stress were also assessed in PASMCs. Results: We found that CBD rever …
799 results