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Role of p53 in irinotecan-induced intestinal cell death and mucosal damage.
Bowen JM, Gibson RJ, Stringer AM, Chan TW, Prabowo AS, Cummins AG, Keefe DM. Bowen JM, et al. Anticancer Drugs. 2007 Feb;18(2):197-210. doi: 10.1097/CAD.0b013e328010ef29. Anticancer Drugs. 2007. PMID: 17159606
The role of pro-inflammatory cytokines in cancer treatment-induced alimentary tract mucositis: pathobiology, animal models and cytotoxic drugs.
Logan RM, Stringer AM, Bowen JM, Yeoh AS, Gibson RJ, Sonis ST, Keefe DM. Logan RM, et al. Cancer Treat Rev. 2007 Aug;33(5):448-60. doi: 10.1016/j.ctrv.2007.03.001. Epub 2007 May 15. Cancer Treat Rev. 2007. PMID: 17507164 Review.
Gene expression analysis of multiple gastrointestinal regions reveals activation of common cell regulatory pathways following cytotoxic chemotherapy.
Bowen JM, Gibson RJ, Tsykin A, Stringer AM, Logan RM, Keefe DM. Bowen JM, et al. Int J Cancer. 2007 Oct 15;121(8):1847-56. doi: 10.1002/ijc.22895. Int J Cancer. 2007. PMID: 17594691
A novel animal model to investigate fractionated radiotherapy-induced alimentary mucositis: the role of apoptosis, p53, nuclear factor-kappaB, COX-1, and COX-2.
Yeoh AS, Gibson RJ, Yeoh EE, Bowen JM, Stringer AM, Giam KA, Keefe DM. Yeoh AS, et al. Mol Cancer Ther. 2007 Aug;6(8):2319-27. doi: 10.1158/1535-7163.MCT-07-0113. Mol Cancer Ther. 2007. PMID: 17699727
Characterisation of mucosal changes in the alimentary tract following administration of irinotecan: implications for the pathobiology of mucositis.
Logan RM, Gibson RJ, Bowen JM, Stringer AM, Sonis ST, Keefe DM. Logan RM, et al. Cancer Chemother Pharmacol. 2008 Jun;62(1):33-41. doi: 10.1007/s00280-007-0570-0. Epub 2007 Aug 17. Cancer Chemother Pharmacol. 2008. PMID: 17703303
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