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Novel potent inhibitors of A. thaliana cytokinin oxidase/dehydrogenase.
Zatloukal M, Gemrotová M, Dolezal K, Havlícek L, Spíchal L, Strnad M. Zatloukal M, et al. Among authors: strnad m. Bioorg Med Chem. 2008 Oct 15;16(20):9268-75. doi: 10.1016/j.bmc.2008.09.008. Epub 2008 Sep 7. Bioorg Med Chem. 2008. PMID: 18818088
Cytokinin-derived cyclin-dependent kinase inhibitors: synthesis and cdc2 inhibitory activity of olomoucine and related compounds.
Havlícek L, Hanus J, Veselý J, Leclerc S, Meijer L, Shaw G, Strnad M. Havlícek L, et al. Among authors: strnad m. J Med Chem. 1997 Feb 14;40(4):408-12. doi: 10.1021/jm960666x. J Med Chem. 1997. PMID: 9046330
Inhibition of cdk with OC and related compounds clearly arrests cell proliferation of many tumor cell lines at G1/S and G2/M transitions and also triggers apoptosis in the target tumor cells in vitro and in vivo. ...
Inhibition of cdk with OC and related compounds clearly arrests cell proliferation of many tumor cell lines at G1/S and G2/M transiti …
Induction of apoptosis and regression of spontaneous dog melanoma following in vivo application of synthetic cyclin-dependent kinase inhibitor olomoucine.
Hajdúch M, Kolár Z, Novotný R, Hanus J, Mihál V, Hlobílková A, Nosková V, Strnad M. Hajdúch M, et al. Among authors: strnad m. Anticancer Drugs. 1997 Nov;8(10):1007-13. doi: 10.1097/00001813-199711000-00012. Anticancer Drugs. 1997. PMID: 9436644
Cytokinins as inhibitors of plant amine oxidase.
Galuszka P, Sebela M, Luhová L, Zajoncová L, Frébort I, Strnad M, Pec P. Galuszka P, et al. Among authors: strnad m. J Enzyme Inhib. 1998 Sep;13(6):457-63. doi: 10.3109/14756369809020549. J Enzyme Inhib. 1998. PMID: 9825308
Synthetic cyclin dependent kinase inhibitors. New generation of potent anti-cancer drugs.
Hajdúch M, Havlíèek L, Veselý J, Novotný R, Mihál V, Strnad M. Hajdúch M, et al. Among authors: strnad m. Adv Exp Med Biol. 1999;457:341-53. Adv Exp Med Biol. 1999. PMID: 10500810 Review.
Docking-based development of purine-like inhibitors of cyclin-dependent kinase-2.
Otyepka M, Krystof V, Havlícek L, Siglerová V, Strnad M, Koca J. Otyepka M, et al. Among authors: strnad m. J Med Chem. 2000 Jun 29;43(13):2506-13. doi: 10.1021/jm990506w. J Med Chem. 2000. PMID: 10891109
Preparation, physicochemical properties and biological activity of copper(II) complexes with 6-(2-chlorobenzylamino)purine (HL1) or 6-(3-chlorobenzylamino)purine (HL2). The single-crystal X-ray structure of.
Trávnícek Z, Malon M, Sindelál Z, Dolezal K, Rolcík J, Krystof V, Strnad M, Marek J. Trávnícek Z, et al. Among authors: strnad m. J Inorg Biochem. 2001 Mar;84(1-2):23-32. doi: 10.1016/s0162-0134(00)00218-x. J Inorg Biochem. 2001. PMID: 11330478
Synthetic inhibitors of CDKs induce different responses in androgen sensitive and androgen insensitive prostatic cancer cell lines.
Mad'arová J, Lukesová M, Hlobilková A, Strnad M, Vojtesek B, Lenobel R, Hajdúch M, Murray PG, Perera S, Kolár Z. Mad'arová J, et al. Among authors: strnad m. Mol Pathol. 2002 Aug;55(4):227-34. doi: 10.1136/mp.55.4.227. Mol Pathol. 2002. PMID: 12147712 Free PMC article.
Synthesis and biological activity of olomoucine II.
Krystof V, Lenobel R, Havlícek L, Kuzma M, Strnad M. Krystof V, et al. Among authors: strnad m. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3283-6. doi: 10.1016/s0960-894x(02)00693-5. Bioorg Med Chem Lett. 2002. PMID: 12392733
Mixed ligand complexes of platinum(II) and palladium(II) with cytokinin-derived compounds Bohemine and Olomoucine: X-ray structure of [Pt(BohH+-N7)Cl(3)].9/5H2O [Boh=6-(benzylamino)-2-[(3-(hydroxypropyl)-amino]-9-isopropylpurine, Bohemine].
Trávnícek Z, Malon M, Zatloukal M, Dolezal K, Strnad M, Marek J. Trávnícek Z, et al. Among authors: strnad m. J Inorg Biochem. 2003 Apr 1;94(4):307-16. doi: 10.1016/s0162-0134(03)00051-5. J Inorg Biochem. 2003. PMID: 12667701
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