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Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase.

Uyttenhove C, Pilotte L, Théate I, Stroobant V, Colau D, Parmentier N, Boon T, Van den Eynde BJ. Uyttenhove C, et al. Among authors: stroobant v. Nat Med. 2003 Oct;9(10):1269-74. doi: 10.1038/nm934. Epub 2003 Sep 21. Nat Med. 2003. PMID: 14502282

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Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer.

Field S, Uyttenhove C, Stroobant V, Cheou P, Donckers D, Coutelier JP, Simpson PT, Cummings MC, Saunus JM, Reid LE, Kutasovic JR, McNicol AM, Kim BR, Kim JH, Lakhani SR, Neville AM, Van Snick J, Jat PS. Field S, et al. Among authors: stroobant v. Int J Cancer. 2016 Apr 15;138(8):1959-70. doi: 10.1002/ijc.29946. Epub 2015 Dec 21. Int J Cancer. 2016. PMID: 26619948 Free article.

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Constitutive IDO1 Expression in Human Tumors Is Driven by Cyclooxygenase-2 and Mediates Intrinsic Immune Resistance.

Hennequart M, Pilotte L, Cane S, Hoffmann D, Stroobant V, Plaen E, Van den Eynde BJ. Hennequart M, et al. Among authors: stroobant v. Cancer Immunol Res. 2017 Aug;5(8):695-709. doi: 10.1158/2326-6066.CIR-16-0400. Epub 2017 Jul 21. Cancer Immunol Res. 2017. PMID: 28765120

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A conserved phosphatase destroys toxic glycolytic side products in mammals and yeast.

Collard F, Baldin F, Gerin I, Bolsée J, Noël G, Graff J, Veiga-da-Cunha M, Stroobant V, Vertommen D, Houddane A, Rider MH, Linster CL, Van Schaftingen E, Bommer GT. Collard F, et al. Among authors: stroobant v. Nat Chem Biol. 2016 Aug;12(8):601-7. doi: 10.1038/nchembio.2104. Epub 2016 Jun 13. Nat Chem Biol. 2016. PMID: 27294321

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A short treatment with galactomannan GM-CT-01 corrects the functions of freshly isolated human tumor-infiltrating lymphocytes.

Demotte N, Bigirimana R, Wieërs G, Stroobant V, Squifflet JL, Carrasco J, Thielemans K, Baurain JF, Van Der Smissen P, Courtoy PJ, van der Bruggen P. Demotte N, et al. Among authors: stroobant v. Clin Cancer Res. 2014 Apr 1;20(7):1823-33. doi: 10.1158/1078-0432.CCR-13-2459. Epub 2014 Feb 13. Clin Cancer Res. 2014. PMID: 24526733

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Database of T cell-defined human tumor antigens: the 2013 update.

Vigneron N, Stroobant V, Van den Eynde BJ, van der Bruggen P. Vigneron N, et al. Among authors: stroobant v. Cancer Immun. 2013 Jul 15;13:15. Print 2013. Cancer Immun. 2013. PMID: 23882160 Free PMC article. Review.

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Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules.

Guillaume B, Chapiro J, Stroobant V, Colau D, Van Holle B, Parvizi G, Bousquet-Dubouch MP, Théate I, Parmentier N, Van den Eynde BJ. Guillaume B, et al. Among authors: stroobant v. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18599-604. doi: 10.1073/pnas.1009778107. Epub 2010 Oct 11. Proc Natl Acad Sci U S A. 2010. PMID: 20937868 Free PMC article.

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Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes.

Demotte N, Stroobant V, Courtoy PJ, Van Der Smissen P, Colau D, Luescher IF, Hivroz C, Nicaise J, Squifflet JL, Mourad M, Godelaine D, Boon T, van der Bruggen P. Demotte N, et al. Among authors: stroobant v. Immunity. 2008 Mar;28(3):414-24. doi: 10.1016/j.immuni.2008.01.011. Immunity. 2008. PMID: 18342010 Free article.

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Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase.

Pilotte L, Larrieu P, Stroobant V, Colau D, Dolusic E, Frédérick R, De Plaen E, Uyttenhove C, Wouters J, Masereel B, Van den Eynde BJ. Pilotte L, et al. Among authors: stroobant v. Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2497-502. doi: 10.1073/pnas.1113873109. Epub 2012 Jan 30. Proc Natl Acad Sci U S A. 2012. PMID: 22308364 Free PMC article.

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Antigen spreading contributes to MAGE vaccination-induced regression of melanoma metastases.

Corbière V, Chapiro J, Stroobant V, Ma W, Lurquin C, Lethé B, van Baren N, Van den Eynde BJ, Boon T, Coulie PG. Corbière V, et al. Among authors: stroobant v. Cancer Res. 2011 Feb 15;71(4):1253-62. doi: 10.1158/0008-5472.CAN-10-2693. Epub 2011 Jan 7. Cancer Res. 2011. PMID: 21216894 Free article.

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