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Inhibitors of cyclic AMP phosphodiesterase. 3. Synthesis and biological evaluation of pyrido and imidazolyl analogues of 1,2,3,5-tetrahydro-2-oxoimidazo[2,1-b]quinazoline.
Venuti MC, Stephenson RA, Alvarez R, Bruno JJ, Strosberg AM. Venuti MC, et al. Among authors: strosberg am. J Med Chem. 1988 Nov;31(11):2136-45. doi: 10.1021/jm00119a014. J Med Chem. 1988. PMID: 2846839
Inhibitors of cyclic AMP phosphodiesterase. 4. Synthesis and evaluation of potential prodrugs of lixazinone (N-cyclohexyl-N-methyl-4-[(1,2,3,5-tetrahydro-2- oxoimidazo[2,1-b]quinazolin-7-yl)-oxy]butyramide, RS-82856).
Venuti MC, Alvarez R, Bruno JJ, Strosberg AM, Gu L, Chiang HS, Massey IJ, Chu N, Fried JH. Venuti MC, et al. Among authors: strosberg am. J Med Chem. 1988 Nov;31(11):2145-52. doi: 10.1021/jm00119a015. J Med Chem. 1988. PMID: 2846840
Effects of enprostil on cardiovascular and respiratory parameters in the dog, and on hematologic parameters in the rat, monkey, and human.
Johnson LG, Bruno JJ, Allely MC, Eglen RM, Chang K, Yang D, Alps BJ, Rosenkranz RP, Strosberg AM. Johnson LG, et al. Among authors: strosberg am. Arzneimittelforschung. 1989 Nov;39(11):1443-8. Arzneimittelforschung. 1989. PMID: 2515862
A potent and selective inhibitor of cyclic AMP phosphodiesterase with potential cardiotonic and antithrombotic properties.
Alvarez R, Banerjee GL, Bruno JJ, Jones GL, Littschwager K, Strosberg AM, Venuti MC. Alvarez R, et al. Among authors: strosberg am. Mol Pharmacol. 1986 Jun;29(6):554-60. Mol Pharmacol. 1986. PMID: 3012320
Effects of RS-59022-198 on the uptake and release of norepinephrine in isolated rat hearts.
Jacobson LO, Lee C, Clarke D, Strosberg AM, Smith WL. Jacobson LO, et al. Among authors: strosberg am. Proc West Pharmacol Soc. 1992;35:73-5. Proc West Pharmacol Soc. 1992. PMID: 1502243 No abstract available.
Antihypertensive 9-substituted 1-oxa-4,9-diazaspiro[5.5]undecan-3-ones.
Clark RD, Caroon JM, Repke DB, Strosberg AM, Bitter SM, Okada MD, Michel AD, Whiting RL. Clark RD, et al. J Med Chem. 1983 Jun;26(6):855-61. doi: 10.1021/jm00360a013. J Med Chem. 1983. PMID: 6133954
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