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PI 3-kinase p110beta: a new target for antithrombotic therapy.
Jackson SP, Schoenwaelder SM, Goncalves I, Nesbitt WS, Yap CL, Wright CE, Kenche V, Anderson KE, Dopheide SM, Yuan Y, Sturgeon SA, Prabaharan H, Thompson PE, Smith GD, Shepherd PR, Daniele N, Kulkarni S, Abbott B, Saylik D, Jones C, Lu L, Giuliano S, Hughan SC, Angus JA, Robertson AD, Salem HH. Jackson SP, et al. Among authors: sturgeon sa. Nat Med. 2005 May;11(5):507-14. doi: 10.1038/nm1232. Epub 2005 Apr 17. Nat Med. 2005. PMID: 15834429 Free article.
Identification of a unique co-operative phosphoinositide 3-kinase signaling mechanism regulating integrin alpha IIb beta 3 adhesive function in platelets.
Schoenwaelder SM, Ono A, Sturgeon S, Chan SM, Mangin P, Maxwell MJ, Turnbull S, Mulchandani M, Anderson K, Kauffenstein G, Rewcastle GW, Kendall J, Gachet C, Salem HH, Jackson SP. Schoenwaelder SM, et al. J Biol Chem. 2007 Sep 28;282(39):28648-28658. doi: 10.1074/jbc.M704358200. Epub 2007 Aug 2. J Biol Chem. 2007. PMID: 17673465 Free article.
Novel role of platelets in mediating inflammatory responses and ventricular rupture or remodeling following myocardial infarction.
Liu Y, Gao XM, Fang L, Jennings NL, Su Y, Q X, Samson AL, Kiriazis H, Wang XF, Shan L, Sturgeon SA, Medcalf RL, Jackson SP, Dart AM, Du XJ. Liu Y, et al. Among authors: sturgeon sa. Arterioscler Thromb Vasc Biol. 2011 Apr;31(4):834-41. doi: 10.1161/ATVBAHA.110.220467. Epub 2011 Jan 20. Arterioscler Thromb Vasc Biol. 2011. PMID: 21252067
14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function.
Schoenwaelder SM, Darbousset R, Cranmer SL, Ramshaw HS, Orive SL, Sturgeon S, Yuan Y, Yao Y, Krycer JR, Woodcock J, Maclean J, Pitson S, Zheng Z, Henstridge DC, van der Wal D, Gardiner EE, Berndt MC, Andrews RK, James DE, Lopez AF, Jackson SP. Schoenwaelder SM, et al. Nat Commun. 2016 Sep 27;7:12862. doi: 10.1038/ncomms12862. Nat Commun. 2016. PMID: 27670677 Free PMC article.
21 results