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Cumulative mutations affecting sterol biosynthesis in the yeast Saccharomyces cerevisiae result in synthetic lethality that is suppressed by alterations in sphingolipid profiles.
Valachovic M, Bareither BM, Shah Alam Bhuiyan M, Eckstein J, Barbuch R, Balderes D, Wilcox L, Sturley SL, Dickson RC, Bard M. Valachovic M, et al. Among authors: sturley sl. Genetics. 2006 Aug;173(4):1893-908. doi: 10.1534/genetics.105.053025. Epub 2006 May 15. Genetics. 2006. PMID: 16702413 Free PMC article.
Sterol esterification in yeast: a two-gene process.
Yang H, Bard M, Bruner DA, Gleeson A, Deckelbaum RJ, Aljinovic G, Pohl TM, Rothstein R, Sturley SL. Yang H, et al. Among authors: sturley sl. Science. 1996 May 31;272(5266):1353-6. doi: 10.1126/science.272.5266.1353. Science. 1996. PMID: 8650549
Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution.
Malathi K, Higaki K, Tinkelenberg AH, Balderes DA, Almanzar-Paramio D, Wilcox LJ, Erdeniz N, Redican F, Padamsee M, Liu Y, Khan S, Alcantara F, Carstea ED, Morris JA, Sturley SL. Malathi K, et al. Among authors: sturley sl. J Cell Biol. 2004 Feb 16;164(4):547-56. doi: 10.1083/jcb.200310046. J Cell Biol. 2004. PMID: 14970192 Free PMC article.
Sterols and sphingolipids: dynamic duo or partners in crime?
Gulati S, Liu Y, Munkacsi AB, Wilcox L, Sturley SL. Gulati S, et al. Among authors: sturley sl. Prog Lipid Res. 2010 Oct;49(4):353-65. doi: 10.1016/j.plipres.2010.03.003. Epub 2010 Apr 1. Prog Lipid Res. 2010. PMID: 20362613 Free PMC article. Review.
79 results