Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

46 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Cell death by necrosis, a regulated way to go.
Henriquez M, Armisén R, Stutzin A, Quest AF. Henriquez M, et al. Curr Mol Med. 2008 May;8(3):187-206. doi: 10.2174/156652408784221289. Curr Mol Med. 2008. PMID: 18473819 Review.
Apoptosis is a programmed form of cell death with well-defined morphological traits that are often associated with activation of caspases. ...These findings have changed our view of necrosis as a passive and essentially accidental form of cell death to that of an ac …
Apoptosis is a programmed form of cell death with well-defined morphological traits that are often associated with activation of casp …
Activation of H2O2-induced VSOR Cl- currents in HTC cells require phospholipase Cgamma1 phosphorylation and Ca2+ mobilisation.
Varela D, Simon F, Olivero P, Armisén R, Leiva-Salcedo E, Jørgensen F, Sala F, Stutzin A. Varela D, et al. Cell Physiol Biochem. 2007;20(6):773-80. doi: 10.1159/000110437. Cell Physiol Biochem. 2007. PMID: 17982259
In rat hepatoma (HTC) cells, H(2)O(2) elicited a transient increase in tyrosine phosphorylation of phospholipase Cgamma1 (PLCgamma1) that was blocked by PP2, a Src-family protein kinases inhibitor. ...Furthermore, in cells that overexpress a phosphorylation-d …
In rat hepatoma (HTC) cells, H(2)O(2) elicited a transient increase in tyrosine phosphorylation of phospholipase Cgamma1 (PLCgamma1) …
NAD(P)H oxidase-derived H(2)O(2) signals chloride channel activation in cell volume regulation and cell proliferation.
Varela D, Simon F, Riveros A, Jørgensen F, Stutzin A. Varela D, et al. J Biol Chem. 2004 Apr 2;279(14):13301-4. doi: 10.1074/jbc.C400020200. Epub 2004 Feb 3. J Biol Chem. 2004. PMID: 14761962
It is concluded that NAD(P)H oxidase-derived H(2)O(2) is the common signal transducing molecule that mediates the activation of these ubiquitously expressed anion channels under a variety of physiological conditions....
It is concluded that NAD(P)H oxidase-derived H(2)O(2) is the common signal transducing molecule that mediates the activation of these ubiqui …
Non-selective cation channels and oxidative stress-induced cell swelling.
Simon F, Varela D, Riveros A, Eguiguren AL, Stutzin A. Simon F, et al. Biol Res. 2002;35(2):215-22. doi: 10.4067/s0716-97602002000200013. Biol Res. 2002. PMID: 12415739
Necrosis is considered as a non-specific form of cell death that induces tissue inflammation and is preceded by cell swelling. ...The ensuing Na+ influx initiates via positive feedback a series of metabolic and electrolytic disturbances, resulting in cell death by n …
Necrosis is considered as a non-specific form of cell death that induces tissue inflammation and is preceded by cell swelling. ...The …
Hydrogen peroxide removes TRPM4 current desensitization conferring increased vulnerability to necrotic cell death.
Simon F, Leiva-Salcedo E, Armisén R, Riveros A, Cerda O, Varela D, Eguiguren AL, Olivero P, Stutzin A. Simon F, et al. Among authors: stutzin a. J Biol Chem. 2010 Nov 26;285(48):37150-8. doi: 10.1074/jbc.M110.155390. Epub 2010 Sep 30. J Biol Chem. 2010. PMID: 20884614 Free PMC article.
TRPM4 enhances cell proliferation through up-regulation of the β-catenin signaling pathway.
Armisén R, Marcelain K, Simon F, Tapia JC, Toro J, Quest AF, Stutzin A. Armisén R, et al. J Cell Physiol. 2011 Jan;226(1):103-9. doi: 10.1002/jcp.22310. J Cell Physiol. 2011. PMID: 20625999
Here we show that reducing TRPM4 expression decreases proliferation of HeLa cells, a cervical cancer-derived cell line. In this cell line, constitutive TRPM4 silencing promoted GSK-3β-dependent degradation of β-catenin and reduced β-catenin/Tcf/Lef-dependent transcription. …
Here we show that reducing TRPM4 expression decreases proliferation of HeLa cells, a cervical cancer-derived cell line. In this cell …
Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells.
Villena J, Henriquez M, Torres V, Moraga F, Díaz-Elizondo J, Arredondo C, Chiong M, Olea-Azar C, Stutzin A, Lavandero S, Quest AF. Villena J, et al. Free Radic Biol Med. 2008 Mar 15;44(6):1146-60. doi: 10.1016/j.freeradbiomed.2007.12.017. Epub 2007 Dec 23. Free Radic Biol Med. 2008. PMID: 18191646
Cell-permeable, C6-ceramide (C6), but not dihydro-C6-ceramide (DH-C6), induced necrosis in a time- and dose-dependent fashion. ...Necrotic cell death observed following C6 exposure was associated with a pronounced decrease in ATP levels and Tiron significantly delay …
Cell-permeable, C6-ceramide (C6), but not dihydro-C6-ceramide (DH-C6), induced necrosis in a time- and dose-dependent fashion. ...Nec …
Hydroxyl radical activation of a Ca(2+)-sensitive nonselective cation channel involved in epithelial cell necrosis.
Simon F, Varela D, Eguiguren AL, Díaz LF, Sala F, Stutzin A. Simon F, et al. Am J Physiol Cell Physiol. 2004 Oct;287(4):C963-70. doi: 10.1152/ajpcell.00041.2004. Epub 2004 May 26. Am J Physiol Cell Physiol. 2004. PMID: 15163619
In a previous work the involvement of a fenamate-sensitive Ca(2+)-activated nonselective cation channel (NSCC) in free radical-induced rat liver cell necrosis was demonstrated (5). Therefore, we studied the effect of radical oxygen species and oxidizing agents on th …
In a previous work the involvement of a fenamate-sensitive Ca(2+)-activated nonselective cation channel (NSCC) in free radical …
TRPM4 regulates Akt/GSK3-β activity and enhances β-catenin signaling and cell proliferation in prostate cancer cells.
Sagredo AI, Sagredo EA, Cappelli C, Báez P, Andaur RE, Blanco C, Tapia JC, Echeverría C, Cerda O, Stutzin A, Simon F, Marcelain K, Armisén R. Sagredo AI, et al. Among authors: stutzin a. Mol Oncol. 2018 Feb;12(2):151-165. doi: 10.1002/1878-0261.12100. Epub 2017 Dec 30. Mol Oncol. 2018. PMID: 28614631 Free PMC article.
Casein kinase-mediated phosphorylation of serine 839 is necessary for basolateral localization of the Ca²⁺-activated non-selective cation channel TRPM4.
Cerda O, Cáceres M, Park KS, Leiva-Salcedo E, Romero A, Varela D, Trimmer JS, Stutzin A. Cerda O, et al. Among authors: stutzin a. Pflugers Arch. 2015 Aug;467(8):1723-1732. doi: 10.1007/s00424-014-1610-3. Epub 2014 Sep 18. Pflugers Arch. 2015. PMID: 25231975 Free PMC article.
46 results
Jump to page
Feedback