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Monomeric structure of the cardioprotective chemokine SDF-1/CXCL12.
Veldkamp CT, Ziarek JJ, Su J, Basnet H, Lennertz R, Weiner JJ, Peterson FC, Baker JE, Volkman BF. Veldkamp CT, et al. Among authors: su j. Protein Sci. 2009 Jul;18(7):1359-69. doi: 10.1002/pro.167. Protein Sci. 2009. PMID: 19551879 Free PMC article.
Heparin oligosaccharides inhibit chemokine (CXC motif) ligand 12 (CXCL12) cardioprotection by binding orthogonal to the dimerization interface, promoting oligomerization, and competing with the chemokine (CXC motif) receptor 4 (CXCR4) N terminus.
Ziarek JJ, Veldkamp CT, Zhang F, Murray NJ, Kartz GA, Liang X, Su J, Baker JE, Linhardt RJ, Volkman BF. Ziarek JJ, et al. Among authors: su j. J Biol Chem. 2013 Jan 4;288(1):737-46. doi: 10.1074/jbc.M112.394064. Epub 2012 Nov 12. J Biol Chem. 2013. PMID: 23148226 Free PMC article.
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