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NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Zhao T, Zhang J, Lei H, Meng Y, Cheng H, Zhao Y, Geng G, Mu C, Chen L, Liu Q, Luo Q, Zhang C, Long Y, Su J, Wang Y, Li Z, Sun J, Chen G, Li Y, Liao X, Shang Y, Hu G, Chen Q, Zhu Y. Zhao T, et al. Among authors: su j. EMBO J. 2023 Aug 15;42(16):e113258. doi: 10.15252/embj.2022113258. Epub 2023 Jul 6. EMBO J. 2023. PMID: 37409632 Free PMC article.
NRF1-mediated innate immune response drives inflammaging.
Lei H, Zhao T, Zhang J, Long Y, Chen Y, Zhu Y, Meng Y, Tang Y, Liu X, Sun J, Li Z, Su J, Gong F, Chen G, Sun B, Chen Y, Chen Q, Li Y, Zhu Y. Lei H, et al. Among authors: su j. Nat Commun. 2025 Dec 11;16(1):11367. doi: 10.1038/s41467-025-66368-6. Nat Commun. 2025. PMID: 41381492 Free PMC article.
Tandem-Mass-Tag Based Proteomic Analysis Facilitates Analyzing Critical Factors of Porous Silicon Nanoparticles in Determining Their Biological Responses under Diseased Condition.
Li Y, Liu Z, Li L, Lian W, He Y, Khalil E, Mäkilä E, Zhang W, Torrieri G, Liu X, Su J, Xiu Y, Fontana F, Salonen J, Hirvonen J, Liu W, Zhang H, Santos HA, Deng X. Li Y, et al. Among authors: su j. Adv Sci (Weinh). 2020 Jun 23;7(15):2001129. doi: 10.1002/advs.202001129. eCollection 2020 Aug. Adv Sci (Weinh). 2020. PMID: 32775170 Free PMC article.
PIKfyve inhibitors against SARS-CoV-2 and its variants including Omicron.
Su J, Zheng J, Huang W, Zhang Y, Lv C, Zhang B, Jiang L, Cheng T, Yuan Q, Xia N, Zhang J, Li L, Li L, Deng X. Su J, et al. Signal Transduct Target Ther. 2022 May 24;7(1):167. doi: 10.1038/s41392-022-01025-8. Signal Transduct Target Ther. 2022. PMID: 35610213 Free PMC article. No abstract available.
Discovery of Potent 1,3-Cyclobutane-Containing Dual A2A/A2B Receptor Antagonists with Low Projected Human Dose for the Treatment of Cancer.
Brill ZG, Christian AH, Rico L, Schneider SE, Phillips EM, Winston MS, Krishnamurthy H, Hennessy ET, Mansoor UF, Xiao D, Su J, Liu P, Plummer C, Palmieri A, Vela Ramirez J, Hill A, Dewey W, Tatosian D, Rindgen D, Ogunbodede O, Smotrov N, Piesvaux J, Ciaccio P, Fan P, Afshar R, Daublain P, Presland J, Otte KM, Ali A, Cumming J, Ranganath S, DeMong D. Brill ZG, et al. Among authors: su j. ACS Med Chem Lett. 2026 Apr 14;17(5):1121-1131. doi: 10.1021/acsmedchemlett.6c00027. eCollection 2026 May 14. ACS Med Chem Lett. 2026. PMID: 42157841 Free PMC article.
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