Sucharit Bhakdi - Search Results

Year	Number of Results
2001	1
2002	5
2003	3
2004	4
2005	4
2006	7
2007	1
2008	8
2009	9
2011	2
2012	8
2013	2
2014	1
2016	2
2017	2
2018	1
2019	2
2021	1
2022	2
2024	0

1

Scramblases as Regulators of Proteolytic ADAM Function.

Reiss K, Leitzke S, Seidel J, Sperrhacke M, Bhakdi S. Reiss K, et al. Among authors: bhakdi s. Membranes (Basel). 2022 Feb 4;12(2):185. doi: 10.3390/membranes12020185. Membranes (Basel). 2022. PMID: 35207106 Free PMC article. Review.

2

Influence of Anoctamin-4 and -9 on ADAM10 and ADAM17 Sheddase Function.

Leitzke S, Seidel J, Ahrens B, Schreiber R, Kunzelmann K, Sperrhacke M, Bhakdi S, Reiss K. Leitzke S, et al. Among authors: bhakdi s. Membranes (Basel). 2022 Jan 20;12(2):123. doi: 10.3390/membranes12020123. Membranes (Basel). 2022. PMID: 35207044 Free PMC article.

3

Role of ADAM10 and ADAM17 in Regulating CD137 Function.

Seidel J, Leitzke S, Ahrens B, Sperrhacke M, Bhakdi S, Reiss K. Seidel J, et al. Among authors: bhakdi s. Int J Mol Sci. 2021 Mar 8;22(5):2730. doi: 10.3390/ijms22052730. Int J Mol Sci. 2021. PMID: 33800462 Free PMC article.

4

Mutagenesis of the ADAM17-phosphatidylserine-binding motif leads to embryonic lethality in mice.

Veit M, Ahrens B, Seidel J, Sommer A, Bhakdi S, Reiss K. Veit M, et al. Among authors: bhakdi s. Life Sci Alliance. 2019 Aug 27;2(5):e201900430. doi: 10.26508/lsa.201900430. Print 2019 Oct. Life Sci Alliance. 2019. PMID: 31455669 Free PMC article.

5

ADAM10 sheddase activation is controlled by cell membrane asymmetry.

Bleibaum F, Sommer A, Veit M, Rabe B, Andrä J, Kunzelmann K, Nehls C, Correa W, Gutsmann T, Grötzinger J, Bhakdi S, Reiss K. Bleibaum F, et al. Among authors: bhakdi s. J Mol Cell Biol. 2019 Dec 23;11(11):979-993. doi: 10.1093/jmcb/mjz008. J Mol Cell Biol. 2019. PMID: 30753537 Free PMC article.

6

Anoctamin-6 regulates ADAM sheddase function.

Veit M, Koyro KI, Ahrens B, Bleibaum F, Munz M, Rövekamp H, Andrä J, Schreiber R, Kunzelmann K, Sommer A, Bhakdi S, Reiss K. Veit M, et al. Among authors: bhakdi s. Biochim Biophys Acta Mol Cell Res. 2018 Nov;1865(11 Pt A):1598-1610. doi: 10.1016/j.bbamcr.2018.08.011. Epub 2018 Aug 23. Biochim Biophys Acta Mol Cell Res. 2018. PMID: 30327201 Free article.

7

Extracellular sphingomyelinase activity impairs TNF-α-induced endothelial cell death via ADAM17 activation and TNF receptor 1 shedding.

Sommer A, Düppe M, Baumecker L, Kordowski F, Büch J, Chico JF, Fritsch J, Schütze S, Adam D, Sperrhacke M, Bhakdi S, Reiss K. Sommer A, et al. Among authors: bhakdi s. Oncotarget. 2017 Aug 7;8(42):72584-72596. doi: 10.18632/oncotarget.19983. eCollection 2017 Sep 22. Oncotarget. 2017. PMID: 29069811 Free PMC article.

8

The plasma membrane: Penultimate regulator of ADAM sheddase function.

Reiss K, Bhakdi S. Reiss K, et al. Among authors: bhakdi s. Biochim Biophys Acta Mol Cell Res. 2017 Nov;1864(11 Pt B):2082-2087. doi: 10.1016/j.bbamcr.2017.06.006. Epub 2017 Jun 15. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28624437 Free article. Review.

9

How membrane asymmetry regulates ADAM17 sheddase function.

Sommer A, Bhakdi S, Reiss K. Sommer A, et al. Among authors: bhakdi s. Cell Cycle. 2016 Nov 16;15(22):2995-2996. doi: 10.1080/15384101.2016.1211449. Epub 2016 Jul 27. Cell Cycle. 2016. PMID: 27463373 Free PMC article. No abstract available.

10

Phosphatidylserine exposure is required for ADAM17 sheddase function.

Sommer A, Kordowski F, Büch J, Maretzky T, Evers A, Andrä J, Düsterhöft S, Michalek M, Lorenzen I, Somasundaram P, Tholey A, Sönnichsen FD, Kunzelmann K, Heinbockel L, Nehls C, Gutsmann T, Grötzinger J, Bhakdi S, Reiss K. Sommer A, et al. Among authors: bhakdi s. Nat Commun. 2016 May 10;7:11523. doi: 10.1038/ncomms11523. Nat Commun. 2016. PMID: 27161080 Free PMC article.

11

Malarial anemia: digestive vacuole of Plasmodium falciparum mediates complement deposition on bystander cells to provoke hemophagocytosis.

Dasari P, Fries A, Heber SD, Salama A, Blau IW, Lingelbach K, Bhakdi SC, Udomsangpetch R, Torzewski M, Reiss K, Bhakdi S. Dasari P, et al. Among authors: bhakdi s. Med Microbiol Immunol. 2014 Dec;203(6):383-93. doi: 10.1007/s00430-014-0347-0. Epub 2014 Jul 2. Med Microbiol Immunol. 2014. PMID: 24985035

12

Proteomic profiling of secreted proteins for the hematopoietic support of interleukin-stimulated human umbilical vein endothelial cells.

Bal G, Kamhieh-Milz J, Sterzer V, Al-Samman M, Debski J, Klein O, Kamhieh-Milz S, Bhakdi S, Salama A. Bal G, et al. Among authors: bhakdi s. Cell Transplant. 2013;22(7):1185-99. doi: 10.3727/096368912X657288. Epub 2012 Oct 1. Cell Transplant. 2013. PMID: 23031318 Free article.

13

Complement and atherosclerosis-united to the point of no return?

Torzewski M, Bhakdi S. Torzewski M, et al. Among authors: bhakdi s. Clin Biochem. 2013 Jan;46(1-2):20-5. doi: 10.1016/j.clinbiochem.2012.09.012. Epub 2012 Sep 23. Clin Biochem. 2013. PMID: 23010447 Review.

14

Mechanisms of invasion and persistence of infectious agents.

Bhakdi S. Bhakdi S. Med Microbiol Immunol. 2012 Nov;201(4):407. doi: 10.1007/s00430-012-0275-9. Epub 2012 Sep 23. Med Microbiol Immunol. 2012. PMID: 23001362 No abstract available.

15

Pore-forming bacterial toxins and antimicrobial peptides as modulators of ADAM function.

Reiss K, Bhakdi S. Reiss K, et al. Among authors: bhakdi s. Med Microbiol Immunol. 2012 Nov;201(4):419-26. doi: 10.1007/s00430-012-0260-3. Epub 2012 Sep 13. Med Microbiol Immunol. 2012. PMID: 22972233 Review.

16

Pathogenesis of malaria revisited.

Dasari P, Bhakdi S. Dasari P, et al. Among authors: bhakdi s. Med Microbiol Immunol. 2012 Nov;201(4):599-604. doi: 10.1007/s00430-012-0265-y. Epub 2012 Sep 7. Med Microbiol Immunol. 2012. PMID: 22955244 Review.

17

Melittin modulates keratinocyte function through P2 receptor-dependent ADAM activation.

Sommer A, Fries A, Cornelsen I, Speck N, Koch-Nolte F, Gimpl G, Andrä J, Bhakdi S, Reiss K. Sommer A, et al. Among authors: bhakdi s. J Biol Chem. 2012 Jul 6;287(28):23678-89. doi: 10.1074/jbc.M112.362756. Epub 2012 May 21. J Biol Chem. 2012. PMID: 22613720 Free PMC article.

18

Use of quantitative microbiological analyses to trace origin of contamination of parenteral nutrition solutions.

Bhakdi S, Krämer I, Siegel E, Jansen B, Exner M. Bhakdi S, et al. Med Microbiol Immunol. 2012 May;201(2):231-7. doi: 10.1007/s00430-012-0236-3. Epub 2012 Apr 7. Med Microbiol Immunol. 2012. PMID: 22484833

19

Digestive vacuole of Plasmodium falciparum released during erythrocyte rupture dually activates complement and coagulation.

Dasari P, Heber SD, Beisele M, Torzewski M, Reifenberg K, Orning C, Fries A, Zapf AL, Baumeister S, Lingelbach K, Udomsangpetch R, Bhakdi SC, Reiss K, Bhakdi S. Dasari P, et al. Among authors: bhakdi s. Blood. 2012 May 3;119(18):4301-10. doi: 10.1182/blood-2011-11-392134. Epub 2012 Mar 8. Blood. 2012. PMID: 22403252 Free article.

20

Digestive vacuoles of Plasmodium falciparum are selectively phagocytosed by and impair killing function of polymorphonuclear leukocytes.

Dasari P, Reiss K, Lingelbach K, Baumeister S, Lucius R, Udomsangpetch R, Bhakdi SC, Bhakdi S. Dasari P, et al. Among authors: bhakdi s. Blood. 2011 Nov 3;118(18):4946-56. doi: 10.1182/blood-2011-05-353920. Epub 2011 Sep 12. Blood. 2011. PMID: 21911835 Free article.

21

Unsaturated fatty acids drive disintegrin and metalloproteinase (ADAM)-dependent cell adhesion, proliferation, and migration by modulating membrane fluidity.

Reiss K, Cornelsen I, Husmann M, Gimpl G, Bhakdi S. Reiss K, et al. Among authors: bhakdi s. J Biol Chem. 2011 Jul 29;286(30):26931-42. doi: 10.1074/jbc.M111.243485. Epub 2011 Jun 3. J Biol Chem. 2011. PMID: 21642425 Free PMC article.

22

Human C-reactive protein does not promote atherosclerosis in transgenic rabbits.

Koike T, Kitajima S, Yu Y, Nishijima K, Zhang J, Ozaki Y, Morimoto M, Watanabe T, Bhakdi S, Asada Y, Chen YE, Fan J. Koike T, et al. Among authors: bhakdi s. Circulation. 2009 Nov 24;120(21):2088-94. doi: 10.1161/CIRCULATIONAHA.109.872796. Epub 2009 Nov 9. Circulation. 2009. PMID: 19901190 Free PMC article.

23

Possible hidden hazards of mass vaccination against new influenza A/H1N1: have the cardiovascular risks been adequately weighed?

Bhakdi S, Lackner K, Doerr HW. Bhakdi S, et al. Med Microbiol Immunol. 2009 Nov;198(4):205-9. doi: 10.1007/s00430-009-0130-9. Med Microbiol Immunol. 2009. PMID: 19851782

24

Pore-forming toxins activate MAPK p38 by causing loss of cellular potassium.

Kloft N, Busch T, Neukirch C, Weis S, Boukhallouk F, Bobkiewicz W, Cibis I, Bhakdi S, Husmann M. Kloft N, et al. Among authors: bhakdi s. Biochem Biophys Res Commun. 2009 Aug 7;385(4):503-6. doi: 10.1016/j.bbrc.2009.05.121. Epub 2009 Jun 2. Biochem Biophys Res Commun. 2009. PMID: 19497299

25

Hypersusceptibility of neutrophil granulocytes towards lethal action of free fatty acids contained in enzyme-modified atherogenic low density lipoprotein.

Lux CA, Koschinski A, Dersch K, Husmann M, Bhakdi S. Lux CA, et al. Among authors: bhakdi s. Atherosclerosis. 2009 Nov;207(1):116-22. doi: 10.1016/j.atherosclerosis.2009.04.004. Epub 2009 Apr 11. Atherosclerosis. 2009. PMID: 19423111

26

Pore formation by Vibrio cholerae cytolysin follows the same archetypical mode as beta-barrel toxins from gram-positive organisms.

Löhner S, Walev I, Boukhallouk F, Palmer M, Bhakdi S, Valeva A. Löhner S, et al. Among authors: bhakdi s. FASEB J. 2009 Aug;23(8):2521-8. doi: 10.1096/fj.08-127688. Epub 2009 Mar 10. FASEB J. 2009. PMID: 19276173

27

Investigation of Sudan IV staining areas in aortas of infants and children: possible prelesional stages of atherogenesis.

Torzewski M, Navarro B, Cheng F, Canisius A, Schmidt T, Bhakdi S, Urban R, Lackner KJ. Torzewski M, et al. Among authors: bhakdi s. Atherosclerosis. 2009 Sep;206(1):159-67. doi: 10.1016/j.atherosclerosis.2009.01.038. Epub 2009 Feb 7. Atherosclerosis. 2009. PMID: 19268943

28

Enzymatically hydrolyzed low-density lipoprotein modulates inflammatory responses in endothelial cells.

Fenske D, Dersch K, Lux C, Zipse L, Suriyaphol P, Dragneva Y, Han SR, Bhakdi S, Husmann M. Fenske D, et al. Among authors: bhakdi s. Thromb Haemost. 2008 Dec;100(6):1146-54. Thromb Haemost. 2008. PMID: 19132242

29

Elimination of a bacterial pore-forming toxin by sequential endocytosis and exocytosis.

Husmann M, Beckmann E, Boller K, Kloft N, Tenzer S, Bobkiewicz W, Neukirch C, Bayley H, Bhakdi S. Husmann M, et al. Among authors: bhakdi s. FEBS Lett. 2009 Jan 22;583(2):337-44. doi: 10.1016/j.febslet.2008.12.028. Epub 2008 Dec 25. FEBS Lett. 2009. PMID: 19101547 Free article.

30

Putative identification of an amphipathic alpha-helical sequence in hemolysin of Escherichia coli (HlyA) involved in transmembrane pore formation.

Valeva A, Siegel I, Wylenzek M, Wassenaar TM, Weis S, Heinz N, Schmitt R, Fischer C, Reinartz R, Bhakdi S, Walev I. Valeva A, et al. Among authors: bhakdi s. Biol Chem. 2008 Sep;389(9):1201-7. doi: 10.1515/BC.2008.136. Biol Chem. 2008. PMID: 18713007

31

Endotoxin accelerates atherosclerosis independent of complement activation.

Reifenberg K, Lehr HA, Fan J, Koike T, Wiese E, Küpper I, Sagban TA, Schaefer SC, Zähringer U, Torzewski M, Lackner KJ, Bhakdi S. Reifenberg K, et al. Among authors: bhakdi s. Thromb Res. 2009 Feb;123(4):653-8. doi: 10.1016/j.thromres.2008.06.017. Epub 2008 Aug 9. Thromb Res. 2009. PMID: 18692867 No abstract available.

32

Mast cells determine the magnitude of bacterial toxin-induced skin inflammation.

Metz M, Magerl M, Kühl NF, Valeva A, Bhakdi S, Maurer M. Metz M, et al. Among authors: bhakdi s. Exp Dermatol. 2009 Feb;18(2):160-6. doi: 10.1111/j.1600-0625.2008.00778.x. Epub 2008 Jul 17. Exp Dermatol. 2009. PMID: 18643847

33

Potential protective role of apoprotein J (clusterin) in atherogenesis: binding to enzymatically modified low-density lipoprotein reduces fatty acid-mediated cytotoxicity.

Schwarz M, Spath L, Lux CA, Paprotka K, Torzewski M, Dersch K, Koch-Brandt C, Husmann M, Bhakdi S. Schwarz M, et al. Among authors: bhakdi s. Thromb Haemost. 2008 Jul;100(1):110-8. doi: 10.1160/TH07-12-0737. Thromb Haemost. 2008. PMID: 18612545

34

No effect of C-reactive protein on early atherosclerosis in LDLR-/- / human C-reactive protein transgenic mice.

Torzewski M, Reifenberg K, Cheng F, Wiese E, Küpper I, Crain J, Lackner KJ, Bhakdi S. Torzewski M, et al. Among authors: bhakdi s. Thromb Haemost. 2008 Jan;99(1):196-201. doi: 10.1160/TH07-10-0595. Thromb Haemost. 2008. PMID: 18217154

35

Pro-inflammatory feedback activation cycle evoked by attack of Vibrio cholerae cytolysin on human neutrophil granulocytes.

Valeva A, Walev I, Weis S, Boukhallouk F, Wassenaar TM, Bhakdi S. Valeva A, et al. Among authors: bhakdi s. Med Microbiol Immunol. 2008 Sep;197(3):285-93. doi: 10.1007/s00430-007-0061-2. Epub 2007 Sep 20. Med Microbiol Immunol. 2008. PMID: 17882454

36

[Immunopathogenesis of atherosclerosis: the Mainz hypothesis].

Bhakdi S. Bhakdi S. Med Monatsschr Pharm. 2006 Oct;29(10):356-9. Med Monatsschr Pharm. 2006. PMID: 17058894 Review. German.

37

Pore-forming Staphylococcus aureus alpha-toxin triggers epidermal growth factor receptor-dependent proliferation.

Haugwitz U, Bobkiewicz W, Han SR, Beckmann E, Veerachato G, Shaid S, Biehl S, Dersch K, Bhakdi S, Husmann M. Haugwitz U, et al. Among authors: bhakdi s. Cell Microbiol. 2006 Oct;8(10):1591-600. doi: 10.1111/j.1462-5822.2006.00733.x. Cell Microbiol. 2006. PMID: 16984414

38

Evidence that clustered phosphocholine head groups serve as sites for binding and assembly of an oligomeric protein pore.

Valeva A, Hellmann N, Walev I, Strand D, Plate M, Boukhallouk F, Brack A, Hanada K, Decker H, Bhakdi S. Valeva A, et al. Among authors: bhakdi s. J Biol Chem. 2006 Sep 8;281(36):26014-21. doi: 10.1074/jbc.M601960200. Epub 2006 Jul 9. J Biol Chem. 2006. PMID: 16829693 Free article.

39

Early diagnosis of Acanthamoeba infection during routine cytological examination of cerebrospinal fluid.

Petry F, Torzewski M, Bohl J, Wilhelm-Schwenkmezger T, Scheid P, Walochnik J, Michel R, Zöller L, Werhahn KJ, Bhakdi S, Lackner KJ. Petry F, et al. Among authors: bhakdi s. J Clin Microbiol. 2006 May;44(5):1903-4. doi: 10.1128/JCM.44.5.1903-1904.2006. J Clin Microbiol. 2006. PMID: 16672436 Free PMC article.

40

Differential role of p38 mitogen activated protein kinase for cellular recovery from attack by pore-forming S. aureus alpha-toxin or streptolysin O.

Husmann M, Dersch K, Bobkiewicz W, Beckmann E, Veerachato G, Bhakdi S. Husmann M, et al. Among authors: bhakdi s. Biochem Biophys Res Commun. 2006 Jun 16;344(4):1128-34. doi: 10.1016/j.bbrc.2006.03.241. Epub 2006 Apr 21. Biochem Biophys Res Commun. 2006. PMID: 16643845

41

Why Escherichia coli alpha-hemolysin induces calcium oscillations in mammalian cells--the pore is on its own.

Koschinski A, Repp H, Unver B, Dreyer F, Brockmeier D, Valeva A, Bhakdi S, Walev I. Koschinski A, et al. Among authors: bhakdi s. FASEB J. 2006 May;20(7):973-5. doi: 10.1096/fj.05-4561fje. Epub 2006 Apr 5. FASEB J. 2006. PMID: 16597673

42

Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement.

Avirutnan P, Punyadee N, Noisakran S, Komoltri C, Thiemmeca S, Auethavornanan K, Jairungsri A, Kanlaya R, Tangthawornchaikul N, Puttikhunt C, Pattanakitsakul SN, Yenchitsomanus PT, Mongkolsapaya J, Kasinrerk W, Sittisombut N, Husmann M, Blettner M, Vasanawathana S, Bhakdi S, Malasit P. Avirutnan P, et al. Among authors: bhakdi s. J Infect Dis. 2006 Apr 15;193(8):1078-88. doi: 10.1086/500949. Epub 2006 Mar 9. J Infect Dis. 2006. PMID: 16544248

43

Staphylococcus aureus bicomponent gamma-hemolysins, HlgA, HlgB, and HlgC, can form mixed pores containing all components.

Dalla Serra M, Coraiola M, Viero G, Comai M, Potrich C, Ferreras M, Baba-Moussa L, Colin DA, Menestrina G, Bhakdi S, Prévost G. Dalla Serra M, et al. Among authors: bhakdi s. J Chem Inf Model. 2005 Nov-Dec;45(6):1539-45. doi: 10.1021/ci050175y. J Chem Inf Model. 2005. PMID: 16309251

44

Binding of Escherichia coli hemolysin and activation of the target cells is not receptor-dependent.

Valeva A, Walev I, Kemmer H, Weis S, Siegel I, Boukhallouk F, Wassenaar TM, Chavakis T, Bhakdi S. Valeva A, et al. Among authors: bhakdi s. J Biol Chem. 2005 Nov 4;280(44):36657-63. doi: 10.1074/jbc.M507690200. Epub 2005 Aug 30. J Biol Chem. 2005. PMID: 16131494 Free article.

45

Identification of the membrane penetrating domain of Vibrio cholerae cytolysin as a beta-barrel structure.

Valeva A, Walev I, Boukhallouk F, Wassenaar TM, Heinz N, Hedderich J, Lautwein S, Möcking M, Weis S, Zitzer A, Bhakdi S. Valeva A, et al. Among authors: bhakdi s. Mol Microbiol. 2005 Jul;57(1):124-31. doi: 10.1111/j.1365-2958.2005.04684.x. Mol Microbiol. 2005. PMID: 15948954 Free article.

46

Role of C-reactive protein in atherogenesis: can the apolipoprotein E knockout mouse provide the answer?

Reifenberg K, Lehr HA, Baskal D, Wiese E, Schaefer SC, Black S, Samols D, Torzewski M, Lackner KJ, Husmann M, Blettner M, Bhakdi S. Reifenberg K, et al. Among authors: bhakdi s. Arterioscler Thromb Vasc Biol. 2005 Aug;25(8):1641-6. doi: 10.1161/01.ATV.0000171983.95612.90. Epub 2005 May 26. Arterioscler Thromb Vasc Biol. 2005. PMID: 15920030

47

Enzymatic modification of low-density lipoprotein in the arterial wall: a new role for plasmin and matrix metalloproteinases in atherogenesis.

Torzewski M, Suriyaphol P, Paprotka K, Spath L, Ochsenhirt V, Schmitt A, Han SR, Husmann M, Gerl VB, Bhakdi S, Lackner KJ. Torzewski M, et al. Among authors: bhakdi s. Arterioscler Thromb Vasc Biol. 2004 Nov;24(11):2130-6. doi: 10.1161/01.ATV.0000144016.85221.66. Epub 2004 Sep 2. Arterioscler Thromb Vasc Biol. 2004. PMID: 15345515

48

A cellular metalloproteinase activates Vibrio cholerae pro-cytolysin.

Valeva A, Walev I, Weis S, Boukhallouk F, Wassenaar TM, Endres K, Fahrenholz F, Bhakdi S, Zitzer A. Valeva A, et al. Among authors: bhakdi s. J Biol Chem. 2004 Jun 11;279(24):25143-8. doi: 10.1074/jbc.M313913200. Epub 2004 Apr 5. J Biol Chem. 2004. PMID: 15066987 Free article.

49

Beyond cholesterol: the enigma of atherosclerosis revisited.

Bhakdi S, Lackner KJ, Han SR, Torzewski M, Husmann M. Bhakdi S, et al. Thromb Haemost. 2004 Apr;91(4):639-45. doi: 10.1160/TH03-12-0733. Thromb Haemost. 2004. PMID: 15045123 Review.

50

Possible protective role for C-reactive protein in atherogenesis: complement activation by modified lipoproteins halts before detrimental terminal sequence.

Bhakdi S, Torzewski M, Paprotka K, Schmitt S, Barsoom H, Suriyaphol P, Han SR, Lackner KJ, Husmann M. Bhakdi S, et al. Circulation. 2004 Apr 20;109(15):1870-6. doi: 10.1161/01.CIR.0000124228.08972.26. Epub 2004 Mar 22. Circulation. 2004. PMID: 15037531

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