Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1982 1
1983 1
1985 1
1986 1
1988 1
1990 7
1992 3
1993 2
1994 2
1995 4
1996 4
1997 1
1998 3
1999 5
2000 17
2001 6
2002 5
2003 7
2004 7
2005 4
2006 10
2007 15
2008 15
2009 29
2010 30
2011 43
2012 45
2013 60
2014 76
2015 73
2016 80
2017 88
2018 88
2019 115
2020 109
2021 130
2022 106
2023 115
2024 48

Text availability

Article attribute

Article type

Publication date

Search Results

1,155 results

Results by year

Filters applied: . Clear all
Page 1
Sucralose.
AlDeeb OA, Mahgoub H, Foda NH. AlDeeb OA, et al. Profiles Drug Subst Excip Relat Methodol. 2013;38:423-62. doi: 10.1016/B978-0-12-407691-4.00010-1. Profiles Drug Subst Excip Relat Methodol. 2013. PMID: 23668410 Review.
The ADME profile covered all absorption, distribution, metabolism, and elimination data in addition to pharmacokinetics and pharmacological effects of sucralose. Some nutritional aspects for sucralose in obesity and diabetes are also presented. Both chemical and mic …
The ADME profile covered all absorption, distribution, metabolism, and elimination data in addition to pharmacokinetics and pharmacological …
Toxicological and pharmacokinetic properties of sucralose-6-acetate and its parent sucralose: in vitro screening assays.
Schiffman SS, Scholl EH, Furey TS, Nagle HT. Schiffman SS, et al. J Toxicol Environ Health B Crit Rev. 2023 Aug 18;26(6):307-341. doi: 10.1080/10937404.2023.2213903. Epub 2023 May 29. J Toxicol Environ Health B Crit Rev. 2023. PMID: 37246822 Review.
Sucralose-6-acetate is an intermediate and impurity in the manufacture of sucralose, and recent commercial sucralose samples were found to contain up to 0.67% sucralose-6-acetate. Studies in a rodent model found that sucralose-6-acetate is also
Sucralose-6-acetate is an intermediate and impurity in the manufacture of sucralose, and recent commercial sucralose sa
Sucralose.
[No authors listed] [No authors listed] 2022 Jul 18. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2022 Jul 18. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000579 Free Books & Documents. Review.
Sucralose has been found in the breastmilk of some nursing mothers who report consuming artificially sweetened beverages and sweetener packets in the past 24 hours and in all women given a sucralose-sweetened soda. ...Some authors note that the levels of sucralos
Sucralose has been found in the breastmilk of some nursing mothers who report consuming artificially sweetened beverages and sweetene
Potential Effects of Sucralose and Saccharin on Gut Microbiota: A Review.
Del Pozo S, Gómez-Martínez S, Díaz LE, Nova E, Urrialde R, Marcos A. Del Pozo S, et al. Nutrients. 2022 Apr 18;14(8):1682. doi: 10.3390/nu14081682. Nutrients. 2022. PMID: 35458244 Free PMC article. Review.
Although there is no consensus, current evidence indicates that sucralose and saccharin could influence the gut microbiota. The aim of this study was to analyze the existing scientific evidence on the effects of saccharin and sucralose consumption on gut microbiota …
Although there is no consensus, current evidence indicates that sucralose and saccharin could influence the gut microbiota. The aim o …
The dietary sweetener sucralose is a negative modulator of T cell-mediated responses.
Zani F, Blagih J, Gruber T, Buck MD, Jones N, Hennequart M, Newell CL, Pilley SE, Soro-Barrio P, Kelly G, Legrave NM, Cheung EC, Gilmore IS, Gould AP, Garcia-Caceres C, Vousden KH. Zani F, et al. Nature. 2023 Mar;615(7953):705-711. doi: 10.1038/s41586-023-05801-6. Epub 2023 Mar 15. Nature. 2023. PMID: 36922598 Free PMC article.
Mechanistically, sucralose affects the membrane order of T cells, accompanied by a reduced efficiency of T cell receptor signalling and intracellular calcium mobilization. ...Overall, these findings suggest that a high intake of sucralose can dampen T cell-mediated …
Mechanistically, sucralose affects the membrane order of T cells, accompanied by a reduced efficiency of T cell receptor signalling a …
Critical review of the current literature on the safety of sucralose.
Magnuson BA, Roberts A, Nestmann ER. Magnuson BA, et al. Food Chem Toxicol. 2017 Aug;106(Pt A):324-355. doi: 10.1016/j.fct.2017.05.047. Epub 2017 May 27. Food Chem Toxicol. 2017. PMID: 28558975 Free article. Review.
Sucralose is a non-caloric high intensity sweetener that is approved globally for use in foods and beverages. ...Following the discovery of sweet taste receptors in the gut and studies investigating the activation of these receptors by sucralose lead to numerous hum
Sucralose is a non-caloric high intensity sweetener that is approved globally for use in foods and beverages. ...Following the discov
Effect of sucralose and aspartame on glucose metabolism and gut hormones.
Ahmad SY, Friel JK, Mackay DS. Ahmad SY, et al. Nutr Rev. 2020 Sep 1;78(9):725-746. doi: 10.1093/nutrit/nuz099. Nutr Rev. 2020. PMID: 32065635 Review.
Here, the available evidence of the effects of aspartame and sucralose consumption on glucose metabolism and gut hormones is reviewed. ...Three studies reported decreased insulin sensitivity following sucralose consumption, while 1 trial reported an increase in insu …
Here, the available evidence of the effects of aspartame and sucralose consumption on glucose metabolism and gut hormones is reviewed …
The Effects of Non-Nutritive Artificial Sweeteners, Aspartame and Sucralose, on the Gut Microbiome in Healthy Adults: Secondary Outcomes of a Randomized Double-Blinded Crossover Clinical Trial.
Ahmad SY, Friel J, Mackay D. Ahmad SY, et al. Nutrients. 2020 Nov 6;12(11):3408. doi: 10.3390/nu12113408. Nutrients. 2020. PMID: 33171964 Free PMC article. Clinical Trial.
Non-nutritive artificial sweeteners (NNSs) may have the ability to change the gut microbiota, which could potentially alter glucose metabolism. This study aimed to determine the effect of sucralose and aspartame consumption on gut microbiota composition using realistic dos …
Non-nutritive artificial sweeteners (NNSs) may have the ability to change the gut microbiota, which could potentially alter glucose metaboli …
Short-Term Consumption of Sucralose with, but Not without, Carbohydrate Impairs Neural and Metabolic Sensitivity to Sugar in Humans.
Dalenberg JR, Patel BP, Denis R, Veldhuizen MG, Nakamura Y, Vinke PC, Luquet S, Small DM. Dalenberg JR, et al. Cell Metab. 2020 Mar 3;31(3):493-502.e7. doi: 10.1016/j.cmet.2020.01.014. Cell Metab. 2020. PMID: 32130881 Free PMC article. Clinical Trial.
Whether a similar relationship exists for no- or low-calorie "diet" drinks is a subject of intensive debate and controversy. Here, we demonstrate that consuming seven sucralose-sweetened beverages with, but not without, a carbohydrate over 10 days decreases insulin sensiti …
Whether a similar relationship exists for no- or low-calorie "diet" drinks is a subject of intensive debate and controversy. Here, we demons …
Ten-Week Sucralose Consumption Induces Gut Dysbiosis and Altered Glucose and Insulin Levels in Healthy Young Adults.
Méndez-García LA, Bueno-Hernández N, Cid-Soto MA, De León KL, Mendoza-Martínez VM, Espinosa-Flores AJ, Carrero-Aguirre M, Esquivel-Velázquez M, León-Hernández M, Viurcos-Sanabria R, Ruíz-Barranco A, Cota-Arce JM, Álvarez-Lee A, De León-Nava MA, Meléndez G, Escobedo G. Méndez-García LA, et al. Microorganisms. 2022 Feb 14;10(2):434. doi: 10.3390/microorganisms10020434. Microorganisms. 2022. PMID: 35208888 Free PMC article.
Sucralose consumption alters microbiome and carbohydrate metabolism in mouse models. ...Sucralose consumption increased serum insulin and the area under the glucose curve compared to water. ...
Sucralose consumption alters microbiome and carbohydrate metabolism in mouse models. ...Sucralose consumption increased serum
1,155 results