Suemizu H - Search Results

1

Steady-State Human Pharmacokinetics of Monobutyl Phthalate Predicted by Physiologically Based Pharmacokinetic Modeling Using Single-Dose Data from Humanized-Liver Mice Orally Administered with Dibutyl Phthalate.

Miura T, Uehara S, Mizuno S, Yoshizawa M, Murayama N, Kamiya Y, Shimizu M, Suemizu H, Yamazaki H. Miura T, et al. Among authors: suemizu h. Chem Res Toxicol. 2019 Feb 18;32(2):333-340. doi: 10.1021/acs.chemrestox.8b00361. Epub 2019 Feb 5. Chem Res Toxicol. 2019. PMID: 30652481

2

Overexpression of human H-ras transgene is responsible for tumors induced by chemical carcinogens in mice.

Maruyama C, Tomisawa M, Wakana S, Yamazaki H, Kijima H, Suemizu H, Ohnishi Y, Urano K, Hioki K, Usui T, Nakamura M, Tsuchida T, Mitsumori K, Nomura T, Tamaoki N, Ueyama Y. Maruyama C, et al. Among authors: suemizu h. Oncol Rep. 2001 Mar-Apr;8(2):233-7. doi: 10.3892/or.8.2.233. Oncol Rep. 2001. PMID: 11182032

3

In vivo formation of a glutathione conjugate derived from thalidomide in humanized uPA-NOG mice.

Yamazaki H, Suemizu H, Igaya S, Shimizu M, Shibata N, Nakamura M, Chowdhury G, Guengerich FP. Yamazaki H, et al. Among authors: suemizu h. Chem Res Toxicol. 2011 Mar 21;24(3):287-9. doi: 10.1021/tx200005g. Epub 2011 Feb 7. Chem Res Toxicol. 2011. PMID: 21299192 Free PMC article.

4

In vivo formation of dihydroxylated and glutathione conjugate metabolites derived from thalidomide and 5-Hydroxythalidomide in humanized TK-NOG mice.

Yamazaki H, Suemizu H, Shimizu M, Igaya S, Shibata N, Nakamura M, Chowdhury G, Guengerich FP. Yamazaki H, et al. Among authors: suemizu h. Chem Res Toxicol. 2012 Feb 20;25(2):274-6. doi: 10.1021/tx300009j. Epub 2012 Jan 25. Chem Res Toxicol. 2012. PMID: 22268628 Free PMC article.

5

Plasma concentrations of melengestrol acetate in humans extrapolated from the pharmacokinetics established in in vivo experiments with rats and chimeric mice with humanized liver and physiologically based pharmacokinetic modeling.

Tsukada A, Suemizu H, Murayama N, Takano R, Shimizu M, Nakamura M, Yamazaki H. Tsukada A, et al. Among authors: suemizu h. Regul Toxicol Pharmacol. 2013 Apr;65(3):316-24. doi: 10.1016/j.yrtph.2013.01.008. Epub 2013 Feb 5. Regul Toxicol Pharmacol. 2013. PMID: 23395687

6

In vivo drug interactions of the teratogen thalidomide with midazolam: heterotropic cooperativity of human cytochrome P450 in humanized TK-NOG mice.

Yamazaki H, Suemizu H, Murayama N, Utoh M, Shibata N, Nakamura M, Guengerich FP. Yamazaki H, et al. Among authors: suemizu h. Chem Res Toxicol. 2013 Mar 18;26(3):486-9. doi: 10.1021/tx400008g. Epub 2013 Mar 1. Chem Res Toxicol. 2013. PMID: 23419139 Free PMC article.

7

The human hepatic cell line HepaRG as a possible cell source for the generation of humanized liver TK-NOG mice.

Higuchi Y, Kawai K, Yamazaki H, Nakamura M, Bree F, Guguen-Guillouzo C, Suemizu H. Higuchi Y, et al. Among authors: suemizu h. Xenobiotica. 2014 Jan;44(2):146-53. doi: 10.3109/00498254.2013.836257. Epub 2013 Sep 25. Xenobiotica. 2014. PMID: 24066694 Free PMC article.

8

Thalidomide increases human hepatic cytochrome P450 3A enzymes by direct activation of the pregnane X receptor.

Murayama N, van Beuningen R, Suemizu H, Guillouzo CG, Shibata N, Yajima K, Utoh M, Shimizu M, Chesné C, Nakamura M, Guengerich FP, Houtman R, Yamazaki H. Murayama N, et al. Among authors: suemizu h. Chem Res Toxicol. 2014 Feb 17;27(2):304-308. doi: 10.1021/tx4004374. Epub 2014 Feb 5. Chem Res Toxicol. 2014. PMID: 24460184 Free PMC article.

9

Human plasma concentrations of herbicidal carbamate molinate extrapolated from the pharmacokinetics established in in vivo experiments with chimeric mice with humanized liver and physiologically based pharmacokinetic modeling.

Yamashita M, Suemizu H, Murayama N, Nishiyama S, Shimizu M, Yamazaki H. Yamashita M, et al. Among authors: suemizu h. Regul Toxicol Pharmacol. 2014 Oct;70(1):214-21. doi: 10.1016/j.yrtph.2014.06.028. Epub 2014 Jul 10. Regul Toxicol Pharmacol. 2014. PMID: 25016177

10

Pharmacokinetics and effects on serum cholinesterase activities of organophosphorus pesticides acephate and chlorpyrifos in chimeric mice transplanted with human hepatocytes.

Suemizu H, Sota S, Kuronuma M, Shimizu M, Yamazaki H. Suemizu H, et al. Regul Toxicol Pharmacol. 2014 Nov;70(2):468-73. doi: 10.1016/j.yrtph.2014.08.010. Epub 2014 Aug 23. Regul Toxicol Pharmacol. 2014. PMID: 25158275

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