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IL-22, but not IL-17, dominant environment in cutaneous T-cell lymphoma
Miyagaki T, et al. Clin Cancer Res 2011. Among authors: Suga H. PMID 22048239
PURPOSE: Both patients with cutaneous T-cell lymphoma (CTCL) and those with atopic dermatitis (AD) have pruritus, T(H)2-biased T cells, and a tendency to have bacterial infections, suggesting a common pathologic basis for these two diseases. ...In this study, we investigated expression levels of T(H)22- and T(H)17-related molecules in lesional skin and sera isolated from patients with CTCL. ...
PURPOSE: Both patients with cutaneous T-cell lymphoma (CTCL) and those with atopic dermatitis (AD) have pruritus, T(H)2-biased T cell …
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