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433 results

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T cells specific for α-myosin drive immunotherapy-related myocarditis.
Axelrod ML, Meijers WC, Screever EM, Qin J, Carroll MG, Sun X, Tannous E, Zhang Y, Sugiura A, Taylor BC, Hanna A, Zhang S, Amancherla K, Tai W, Wright JJ, Wei SC, Opalenik SR, Toren AL, Rathmell JC, Ferrell PB, Phillips EJ, Mallal S, Johnson DB, Allison JP, Moslehi JJ, Balko JM. Axelrod ML, et al. Among authors: sugiura a. Nature. 2022 Nov;611(7937):818-826. doi: 10.1038/s41586-022-05432-3. Epub 2022 Nov 16. Nature. 2022. PMID: 36385524 Free PMC article.
Metabolic Barriers to T Cell Function in Tumors.
Sugiura A, Rathmell JC. Sugiura A, et al. J Immunol. 2018 Jan 15;200(2):400-407. doi: 10.4049/jimmunol.1701041. J Immunol. 2018. PMID: 29311381 Free PMC article. Review.
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.
Johnson MO, Wolf MM, Madden MZ, Andrejeva G, Sugiura A, Contreras DC, Maseda D, Liberti MV, Paz K, Kishton RJ, Johnson ME, de Cubas AA, Wu P, Li G, Zhang Y, Newcomb DC, Wells AD, Restifo NP, Rathmell WK, Locasale JW, Davila ML, Blazar BR, Rathmell JC. Johnson MO, et al. Among authors: sugiura a. Cell. 2018 Dec 13;175(7):1780-1795.e19. doi: 10.1016/j.cell.2018.10.001. Epub 2018 Nov 1. Cell. 2018. PMID: 30392958 Free PMC article.
Clinical Features and Multiplatform Molecular Analysis Assist in Understanding Patient Response to Anti-PD-1/PD-L1 in Renal Cell Carcinoma.
Shiuan E, Reddy A, Dudzinski SO, Lim AR, Sugiura A, Hongo R, Young K, Liu XD, Smith CC, O'Neal J, Dahlman KB, McAlister R, Chen B, Ruma K, Roscoe N, Bender J, Ward J, Kim JY, Vaupel C, Bordeaux J, Ganesan S, Mayer TM, Riedlinger GM, Vincent BG, Davis NB, Haake SM, Rathmell JC, Jonasch E, Rini BI, Rathmell WK, Beckermann KE. Shiuan E, et al. Among authors: sugiura a. Cancers (Basel). 2021 Mar 23;13(6):1475. doi: 10.3390/cancers13061475. Cancers (Basel). 2021. PMID: 33806963 Free PMC article.
Cell-programmed nutrient partitioning in the tumour microenvironment.
Reinfeld BI, Madden MZ, Wolf MM, Chytil A, Bader JE, Patterson AR, Sugiura A, Cohen AS, Ali A, Do BT, Muir A, Lewis CA, Hongo RA, Young KL, Brown RE, Todd VM, Huffstater T, Abraham A, O'Neil RT, Wilson MH, Xin F, Tantawy MN, Merryman WD, Johnson RW, Williams CS, Mason EF, Mason FM, Beckermann KE, Vander Heiden MG, Manning HC, Rathmell JC, Rathmell WK. Reinfeld BI, et al. Among authors: sugiura a. Nature. 2021 May;593(7858):282-288. doi: 10.1038/s41586-021-03442-1. Epub 2021 Apr 7. Nature. 2021. PMID: 33828302 Free PMC article.
A guide to interrogating immunometabolism.
Voss K, Hong HS, Bader JE, Sugiura A, Lyssiotis CA, Rathmell JC. Voss K, et al. Among authors: sugiura a. Nat Rev Immunol. 2021 Oct;21(10):637-652. doi: 10.1038/s41577-021-00529-8. Epub 2021 Apr 15. Nat Rev Immunol. 2021. PMID: 33859379 Free PMC article. Review.
MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function.
Sugiura A, Andrejeva G, Voss K, Heintzman DR, Xu X, Madden MZ, Ye X, Beier KL, Chowdhury NU, Wolf MM, Young AC, Greenwood DL, Sewell AE, Shahi SK, Freedman SN, Cameron AM, Foerch P, Bourne T, Garcia-Canaveras JC, Karijolich J, Newcomb DC, Mangalam AK, Rabinowitz JD, Rathmell JC. Sugiura A, et al. Immunity. 2022 Jan 11;55(1):65-81.e9. doi: 10.1016/j.immuni.2021.10.011. Epub 2021 Nov 11. Immunity. 2022. PMID: 34767747 Free PMC article.
Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk.
Greenwood DL, Ramsey HE, Nguyen PTT, Patterson AR, Voss K, Bader JE, Sugiura A, Bacigalupa ZA, Schaefer S, Ye X, Dahunsi DO, Madden MZ, Wellen KE, Savona MR, Ferrell PB, Rathmell JC. Greenwood DL, et al. Among authors: sugiura a. Immunohorizons. 2022 Dec 1;6(12):837-850. doi: 10.4049/immunohorizons.2200086. Immunohorizons. 2022. PMID: 36547387 Free PMC article.
Elevated transferrin receptor impairs T cell metabolism and function in systemic lupus erythematosus.
Voss K, Sewell AE, Krystofiak ES, Gibson-Corley KN, Young AC, Basham JH, Sugiura A, Arner EN, Beavers WN, Kunkle DE, Dickson ME, Needle GA, Skaar EP, Rathmell WK, Ormseth MJ, Major AS, Rathmell JC. Voss K, et al. Among authors: sugiura a. Sci Immunol. 2023 Jan 13;8(79):eabq0178. doi: 10.1126/sciimmunol.abq0178. Epub 2023 Jan 13. Sci Immunol. 2023. PMID: 36638190 Free PMC article.
433 results