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Mutation (Ser284Leu) of neuronal nicotinic acetylcholine receptor alpha 4 subunit associated with frontal lobe epilepsy causes faster desensitization of the rat receptor expressed in oocytes.
Matsushima N, Hirose S, Iwata H, Fukuma G, Yonetani M, Nagayama C, Hamanaka W, Matsunaka Y, Ito M, Kaneko S, Mitsudome A, Sugiyama H. Matsushima N, et al. Among authors: sugiyama h. Epilepsy Res. 2002 Feb;48(3):181-6. doi: 10.1016/s0920-1211(01)00336-9. Epilepsy Res. 2002. PMID: 11904236
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