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Transporters as a determinant of drug clearance and tissue distribution.
Shitara Y, Horie T, Sugiyama Y. Shitara Y, et al. Among authors: sugiyama y. Eur J Pharm Sci. 2006 Apr;27(5):425-46. doi: 10.1016/j.ejps.2005.12.003. Epub 2006 Feb 20. Eur J Pharm Sci. 2006. PMID: 16488580 Review.
Significance of binding to Na,K-ATPase in the tissue distribution of ouabain in guinea pigs.
Harashima H, Mamiya M, Yamazaki M, Sugiyama Y, Sawada Y, Iga T, Hanano M. Harashima H, et al. Among authors: sugiyama y. Pharm Res. 1992 Apr;9(4):474-9. doi: 10.1023/a:1015832127969. Pharm Res. 1992. PMID: 1323099
Kinetic modeling of ouabain tissue distribution based on slow and saturable binding to Na,K-ATPase.
Harashima H, Mamiya M, Yamazaki M, Sawada Y, Iga T, Hanano M, Sugiyama Y. Harashima H, et al. Among authors: sugiyama y. Pharm Res. 1992 Dec;9(12):1607-11. doi: 10.1023/a:1015820610048. Pharm Res. 1992. PMID: 1336859
Kinetic analysis of hepatobiliary transport of vincristine in perfused rat liver. Possible roles of P-glycoprotein in biliary excretion of vincristine.
Watanabe T, Miyauchi S, Sawada Y, Iga T, Hanano M, Inaba M, Sugiyama Y. Watanabe T, et al. Among authors: sugiyama y. J Hepatol. 1992 Sep;16(1-2):77-88. doi: 10.1016/s0168-8278(05)80098-4. J Hepatol. 1992. PMID: 1362433
Importance of the liver in plasma clearance of hepatocyte growth factors in rats.
Liu KX, Kato Y, Narukawa M, Kim DC, Hanano M, Higuchi O, Nakamura T, Sugiyama Y. Liu KX, et al. Among authors: sugiyama y. Am J Physiol. 1992 Nov;263(5 Pt 1):G642-9. doi: 10.1152/ajpgi.1992.263.5.G642. Am J Physiol. 1992. PMID: 1443139
Nonlinear pharmacokinetics of hepatobiliary transport of rose bengal in rats after i.v. bolus administration with varying doses.
Wang HK, Miyachi S, Yamazaki M, Sawada Y, Chung YB, Iga T, Hanano M, Sugiyama Y. Wang HK, et al. Among authors: sugiyama y. Biopharm Drug Dispos. 1992 Dec;13(9):647-62. doi: 10.1002/bdd.2510130903. Biopharm Drug Dispos. 1992. PMID: 1467452
Localization of binding sites for epidermal growth factor (EGF) in rat kidney: evidence for the existence of low affinity EGF binding sites on the brush border membrane.
Kim DC, Hanano M, Kanai Y, Ohnuma N, Sugiyama Y. Kim DC, et al. Among authors: sugiyama y. Pharm Res. 1992 Nov;9(11):1394-401. doi: 10.1023/a:1015846526461. Pharm Res. 1992. PMID: 1475224
'Albumin-mediated transport phenomenon' observed for ligands with high membrane permeability. Effect of the unstirred water layer in the Disse's space of rat liver.
Ichikawa M, Tsao SC, Lin TH, Miyauchi S, Sawada Y, Iga T, Hanano M, Sugiyama Y. Ichikawa M, et al. Among authors: sugiyama y. J Hepatol. 1992 Sep;16(1-2):38-49. doi: 10.1016/s0168-8278(05)80092-3. J Hepatol. 1992. PMID: 1484165
Renal tubular handling of p-aminohippurate and epidermal growth factor (EGF) in filtering and nonfiltering perfused rat kidneys.
Kim DC, Sugiyama Y, Sawada Y, Hanano M. Kim DC, et al. Among authors: sugiyama y. Pharm Res. 1992 Feb;9(2):271-5. doi: 10.1023/a:1018957911614. Pharm Res. 1992. PMID: 1553353
Localization of epidermal growth factor (EGF) binding sites on antiluminal plasma membrane of rat kidney: autoradiographic study using nonfiltering perfused rat kidney.
Kim DC, Sugiyama Y, Kanai Y, Ohnuma N, Hanano M. Kim DC, et al. Among authors: sugiyama y. Pharm Res. 1992 Jan;9(1):40-4. doi: 10.1023/a:1018923609371. Pharm Res. 1992. PMID: 1589408
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