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Positron emission tomography studies using (15R)-16-m-[11C]tolyl-17,18,19,20-tetranorisocarbacyclin methyl ester for the evaluation of hepatobiliary transport.
Takashima T, Nagata H, Nakae T, Cui Y, Wada Y, Kitamura S, Doi H, Suzuki M, Maeda K, Kusuhara H, Sugiyama Y, Watanabe Y. Takashima T, et al. Among authors: sugiyama y. J Pharmacol Exp Ther. 2010 Nov;335(2):314-23. doi: 10.1124/jpet.110.170092. Epub 2010 Aug 17. J Pharmacol Exp Ther. 2010. PMID: 20716623
Dynamic analysis of fluid distribution in the gastrointestinal tract in rats: positron emission tomography imaging after oral administration of nonabsorbable marker, [(18)F]Deoxyfluoropoly(ethylene glycol).
Takashima T, Shingaki T, Katayama Y, Hayashinaka E, Wada Y, Kataoka M, Ozaki D, Doi H, Suzuki M, Ishida S, Hatanaka K, Sugiyama Y, Akai S, Oku N, Yamashita S, Watanabe Y. Takashima T, et al. Among authors: sugiyama y. Mol Pharm. 2013 Jun 3;10(6):2261-9. doi: 10.1021/mp300469m. Epub 2013 May 7. Mol Pharm. 2013. PMID: 23600944
Evaluation of Oatp and Mrp2 activities in hepatobiliary excretion using newly developed positron emission tomography tracer [11C]dehydropravastatin in rats.
Shingaki T, Takashima T, Ijuin R, Zhang X, Onoue T, Katayama Y, Okauchi T, Hayashinaka E, Cui Y, Wada Y, Suzuki M, Maeda K, Kusuhara H, Sugiyama Y, Watanabe Y. Shingaki T, et al. Among authors: sugiyama y. J Pharmacol Exp Ther. 2013 Oct;347(1):193-202. doi: 10.1124/jpet.113.206425. Epub 2013 Aug 7. J Pharmacol Exp Ther. 2013. PMID: 23926287
PET imaging-based evaluation of hepatobiliary transport in humans with (15R)-11C-TIC-Me.
Takashima T, Kitamura S, Wada Y, Tanaka M, Shigihara Y, Ishii H, Ijuin R, Shiomi S, Nakae T, Watanabe Y, Cui Y, Doi H, Suzuki M, Maeda K, Kusuhara H, Sugiyama Y, Watanabe Y. Takashima T, et al. Among authors: sugiyama y. J Nucl Med. 2012 May;53(5):741-8. doi: 10.2967/jnumed.111.098681. Epub 2012 Apr 12. J Nucl Med. 2012. PMID: 22499612 Free article. Clinical Trial.
The synthesis and biodistribution of [(11)C]metformin as a PET probe to study hepatobiliary transport mediated by the multi-drug and toxin extrusion transporter 1 (MATE1) in vivo.
Hume WE, Shingaki T, Takashima T, Hashizume Y, Okauchi T, Katayama Y, Hayashinaka E, Wada Y, Kusuhara H, Sugiyama Y, Watanabe Y. Hume WE, et al. Among authors: sugiyama y. Bioorg Med Chem. 2013 Dec 15;21(24):7584-90. doi: 10.1016/j.bmc.2013.10.041. Epub 2013 Nov 1. Bioorg Med Chem. 2013. PMID: 24238901
2,649 results