Sugiyama Y - Search Results

1

A Clinical Cassette Dosing Study for Evaluating the Contribution of Hepatic OATPs and CYP3A to Drug-Drug Interactions.

Yoshikado T, Maeda K, Furihata S, Terashima H, Nakayama T, Ishigame K, Tsunemoto K, Kusuhara H, Furihata KI, Sugiyama Y. Yoshikado T, et al. Among authors: sugiyama y. Pharm Res. 2017 Aug;34(8):1570-1583. doi: 10.1007/s11095-017-2168-5. Epub 2017 May 8. Pharm Res. 2017. PMID: 28484975

2

DNA methylation profiles of organic anion transporting polypeptide 1B3 in cancer cell lines.

Ichihara S, Kikuchi R, Kusuhara H, Imai S, Maeda K, Sugiyama Y. Ichihara S, et al. Among authors: sugiyama y. Pharm Res. 2010 Mar;27(3):510-6. doi: 10.1007/s11095-010-0064-3. Epub 2010 Feb 4. Pharm Res. 2010. PMID: 20130966

3

Basolateral efflux mediated by multidrug resistance-associated protein 3 (Mrp3/Abcc3) facilitates intestinal absorption of folates in mouse.

Kitamura Y, Kusuhara H, Sugiyama Y. Kitamura Y, et al. Among authors: sugiyama y. Pharm Res. 2010 Apr;27(4):665-72. doi: 10.1007/s11095-009-0047-4. Epub 2010 Feb 11. Pharm Res. 2010. PMID: 20148291

4

The use of hepatocytes to investigate drug uptake transporters.

Maeda K, Sugiyama Y. Maeda K, et al. Among authors: sugiyama y. Methods Mol Biol. 2010;640:327-53. doi: 10.1007/978-1-60761-688-7_18. Methods Mol Biol. 2010. PMID: 20645061

5

Inhibitory effects of p-aminohippurate and probenecid on the renal clearance of adefovir and benzylpenicillin as probe drugs for organic anion transporter (OAT) 1 and OAT3 in humans.

Maeda K, Tian Y, Fujita T, Ikeda Y, Kumagai Y, Kondo T, Tanabe K, Nakayama H, Horita S, Kusuhara H, Sugiyama Y. Maeda K, et al. Among authors: sugiyama y. Eur J Pharm Sci. 2014 Aug 1;59:94-103. doi: 10.1016/j.ejps.2014.04.004. Epub 2014 Apr 18. Eur J Pharm Sci. 2014. PMID: 24747579 Clinical Trial.

6

Clarification of the Mechanism of Clopidogrel-Mediated Drug-Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information.

Kim SJ, Yoshikado T, Ieiri I, Maeda K, Kimura M, Irie S, Kusuhara H, Sugiyama Y. Kim SJ, et al. Among authors: sugiyama y. Drug Metab Dispos. 2016 Oct;44(10):1622-32. doi: 10.1124/dmd.116.070276. Epub 2016 Jul 25. Drug Metab Dispos. 2016. PMID: 27457785

7

Comparison of the Predictability of Human Hepatic Clearance for Organic Anion Transporting Polypeptide Substrate Drugs Between Different In Vitro-In Vivo Extrapolation Approaches.

Izumi S, Nozaki Y, Komori T, Takenaka O, Maeda K, Kusuhara H, Sugiyama Y. Izumi S, et al. Among authors: sugiyama y. J Pharm Sci. 2017 Sep;106(9):2678-2687. doi: 10.1016/j.xphs.2017.02.012. Epub 2017 Feb 24. J Pharm Sci. 2017. PMID: 28238896

8

Small-Dosing Clinical Study: Pharmacokinetic, Pharmacogenomic (SLCO2B1 and ABCG2), and Interaction (Atorvastatin and Grapefruit Juice) Profiles of 5 Probes for OATP2B1 and BCRP.

Kashihara Y, Ieiri I, Yoshikado T, Maeda K, Fukae M, Kimura M, Hirota T, Matsuki S, Irie S, Izumi N, Kusuhara H, Sugiyama Y. Kashihara Y, et al. Among authors: sugiyama y. J Pharm Sci. 2017 Sep;106(9):2688-2694. doi: 10.1016/j.xphs.2017.03.010. Epub 2017 Mar 18. J Pharm Sci. 2017. PMID: 28322941

9

Quantitative Analysis of Complex Drug-Drug Interactions Between Repaglinide and Cyclosporin A/Gemfibrozil Using Physiologically Based Pharmacokinetic Models With In Vitro Transporter/Enzyme Inhibition Data.

Kim SJ, Toshimoto K, Yao Y, Yoshikado T, Sugiyama Y. Kim SJ, et al. Among authors: sugiyama y. J Pharm Sci. 2017 Sep;106(9):2715-2726. doi: 10.1016/j.xphs.2017.04.063. Epub 2017 May 4. J Pharm Sci. 2017. PMID: 28479356

10

Quantitative Analyses of the Influence of Parameters Governing Rate-Determining Process of Hepatic Elimination of Drugs on the Magnitudes of Drug-Drug Interactions via Hepatic OATPs and CYP3A Using Physiologically Based Pharmacokinetic Models.

Yoshikado T, Maeda K, Kusuhara H, Furihata KI, Sugiyama Y. Yoshikado T, et al. Among authors: sugiyama y. J Pharm Sci. 2017 Sep;106(9):2739-2750. doi: 10.1016/j.xphs.2017.05.001. Epub 2017 May 8. J Pharm Sci. 2017. PMID: 28495568

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