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Angiopoietin-like protein 2 increases renal fibrosis by accelerating transforming growth factor-β signaling in chronic kidney disease.
Morinaga J, Kadomatsu T, Miyata K, Endo M, Terada K, Tian Z, Sugizaki T, Tanigawa H, Zhao J, Zhu S, Sato M, Araki K, Iyama K, Tomita K, Mukoyama M, Tomita K, Kitamura K, Oike Y. Morinaga J, et al. Among authors: sugizaki t. Kidney Int. 2016 Feb;89(2):327-41. doi: 10.1016/j.kint.2015.12.021. Epub 2016 Jan 1. Kidney Int. 2016. PMID: 26806834 Free article.
Mice Deficient in Angiopoietin-like Protein 2 (Angptl2) Gene Show Increased Susceptibility to Bacterial Infection Due to Attenuated Macrophage Activity.
Yugami M, Odagiri H, Endo M, Tsutsuki H, Fujii S, Kadomatsu T, Masuda T, Miyata K, Terada K, Tanoue H, Ito H, Morinaga J, Horiguchi H, Sugizaki T, Akaike T, Gotoh T, Takai T, Sawa T, Mizuta H, Oike Y. Yugami M, et al. Among authors: sugizaki t. J Biol Chem. 2016 Sep 2;291(36):18843-52. doi: 10.1074/jbc.M116.720870. Epub 2016 Jul 11. J Biol Chem. 2016. PMID: 27402837 Free PMC article.
Interstitial pneumonia induced by bleomycin treatment is exacerbated in Angptl2-deficient mice.
Motokawa I, Endo M, Terada K, Horiguchi H, Miyata K, Kadomatsu T, Morinaga J, Sugizaki T, Ito T, Araki K, Morioka MS, Manabe I, Samukawa T, Watanabe M, Inoue H, Oike Y. Motokawa I, et al. Among authors: sugizaki t. Am J Physiol Lung Cell Mol Physiol. 2016 Oct 1;311(4):L704-L713. doi: 10.1152/ajplung.00005.2016. Epub 2016 Aug 19. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27542805 Free article.
ANGPTL2 activity in cardiac pathologies accelerates heart failure by perturbing cardiac function and energy metabolism.
Tian Z, Miyata K, Kadomatsu T, Horiguchi H, Fukushima H, Tohyama S, Ujihara Y, Okumura T, Yamaguchi S, Zhao J, Endo M, Morinaga J, Sato M, Sugizaki T, Zhu S, Terada K, Sakaguchi H, Komohara Y, Takeya M, Takeda N, Araki K, Manabe I, Fukuda K, Otsu K, Wada J, Murohara T, Mohri S, Yamashita JK, Sano M, Oike Y. Tian Z, et al. Among authors: sugizaki t. Nat Commun. 2016 Sep 28;7:13016. doi: 10.1038/ncomms13016. Nat Commun. 2016. PMID: 27677409 Free PMC article.
Upregulation of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis.
Tanigawa H, Miyata K, Tian Z, Aoi J, Kadomatsu T, Fukushima S, Ogata A, Takeda N, Zhao J, Zhu S, Terada K, Endo M, Morinaga J, Sugizaki T, Sato M, Morioka MS, Manabe I, Mashimo Y, Hata A, Taketomi Y, Yamamoto K, Murakami M, Araki K, Jinnin M, Ihn H, Oike Y. Tanigawa H, et al. Among authors: sugizaki t. Sci Rep. 2016 Oct 4;6:34690. doi: 10.1038/srep34690. Sci Rep. 2016. PMID: 27698489 Free PMC article.
Bile acid binding resin prevents fat accumulation through intestinal microbiota in high-fat diet-induced obesity in mice.
Kusumoto Y, Irie J, Iwabu K, Tagawa H, Itoh A, Kato M, Kobayashi N, Tanaka K, Kikuchi R, Fujita M, Nakajima Y, Morimoto K, Sugizaki T, Yamada S, Kawai T, Watanabe M, Oike Y, Itoh H. Kusumoto Y, et al. Among authors: sugizaki t. Metabolism. 2017 Jun;71:1-6. doi: 10.1016/j.metabol.2017.02.011. Epub 2017 Feb 27. Metabolism. 2017. PMID: 28521862
Angiopoietin-like protein 2 promotes chondrogenic differentiation during bone growth as a cartilage matrix factor.
Tanoue H, Morinaga J, Yoshizawa T, Yugami M, Itoh H, Nakamura T, Uehara Y, Masuda T, Odagiri H, Sugizaki T, Kadomatsu T, Miyata K, Endo M, Terada K, Ochi H, Takeda S, Yamagata K, Fukuda T, Mizuta H, Oike Y. Tanoue H, et al. Among authors: sugizaki t. Osteoarthritis Cartilage. 2018 Jan;26(1):108-117. doi: 10.1016/j.joca.2017.10.011. Epub 2017 Oct 23. Osteoarthritis Cartilage. 2018. PMID: 29074299 Free article.
47 results