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Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response.
Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. Chen G, et al. Among authors: sun h. Nature. 2018 Aug;560(7718):382-386. doi: 10.1038/s41586-018-0392-8. Epub 2018 Aug 8. Nature. 2018. PMID: 30089911 Free PMC article.
The anti-inflammatory TIPE2 is an inhibitor of the oncogenic Ras.
Gus-Brautbar Y, Johnson D, Zhang L, Sun H, Wang P, Zhang S, Zhang L, Chen YH. Gus-Brautbar Y, et al. Among authors: sun h. Mol Cell. 2012 Mar 9;45(5):610-8. doi: 10.1016/j.molcel.2012.01.006. Epub 2012 Feb 8. Mol Cell. 2012. PMID: 22326055 Free PMC article.
Critical roles of TIPE2 protein in murine experimental colitis.
Lou Y, Sun H, Morrissey S, Porturas T, Liu S, Hua X, Chen YH. Lou Y, et al. Among authors: sun h. J Immunol. 2014 Aug 1;193(3):1064-70. doi: 10.4049/jimmunol.1400415. Epub 2014 Jun 27. J Immunol. 2014. PMID: 24973456 Free PMC article.
TNFAIP8 controls murine intestinal stem cell homeostasis and regeneration by regulating microbiome-induced Akt signaling.
Goldsmith JR, Spitofsky N, Zamani A, Hood R, Boggs A, Li X, Li M, Reiner E, Ayyaz A, Etwebi Z, Lu L, Rivera Guzman J, Bou-Dargham MJ, Cathoupolis T, Hakonarson H, Sun H, Wrana JL, Gonzalez MV, Chen YH. Goldsmith JR, et al. Among authors: sun h. Nat Commun. 2020 May 22;11(1):2591. doi: 10.1038/s41467-020-16379-2. Nat Commun. 2020. PMID: 32444641 Free PMC article.
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