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Physiological loading of joints prevents cartilage degradation through CITED2.
Leong DJ, Li YH, Gu XI, Sun L, Zhou Z, Nasser P, Laudier DM, Iqbal J, Majeska RJ, Schaffler MB, Goldring MB, Cardoso L, Zaidi M, Sun HB. Leong DJ, et al. Among authors: sun l, sun hb. FASEB J. 2011 Jan;25(1):182-91. doi: 10.1096/fj.10-164277. Epub 2010 Sep 8. FASEB J. 2011. PMID: 20826544 Free PMC article.
Events in articular chondrocytes with aging.
Leong DJ, Sun HB. Leong DJ, et al. Among authors: sun hb. Curr Osteoporos Rep. 2011 Dec;9(4):196-201. doi: 10.1007/s11914-011-0070-3. Curr Osteoporos Rep. 2011. PMID: 21912847 Review.
Identification of CITED2 as a negative regulator of fracture healing.
Lee JY, Taub PJ, Wang L, Clark A, Zhu LL, Maharam ER, Leong DJ, Ramcharan M, Li Z, Liu Z, Ma YZ, Sun L, Zaidi M, Majeska RJ, Sun HB. Lee JY, et al. Among authors: sun l, sun hb. Biochem Biophys Res Commun. 2009 Oct 2;387(4):641-5. doi: 10.1016/j.bbrc.2009.07.029. Epub 2009 Jul 14. Biochem Biophys Res Commun. 2009. PMID: 19607804 Free PMC article.
Strain-induced mechanotransduction through primary cilia, extracellular ATP, purinergic calcium signaling, and ERK1/2 transactivates CITED2 and downregulates MMP-1 and MMP-13 gene expression in chondrocytes.
He Z, Leong DJ, Zhuo Z, Majeska RJ, Cardoso L, Spray DC, Goldring MB, Cobelli NJ, Sun HB. He Z, et al. Among authors: sun hb. Osteoarthritis Cartilage. 2016 May;24(5):892-901. doi: 10.1016/j.joca.2015.11.015. Epub 2015 Dec 12. Osteoarthritis Cartilage. 2016. PMID: 26687824 Free article.
Mechanical intervention for maintenance of cartilage and bone.
Sun HB, Cardoso L, Yokota H. Sun HB, et al. Clin Med Insights Arthritis Musculoskelet Disord. 2011;4:65-70. doi: 10.4137/CMAMD.S6982. Epub 2011 Jun 29. Clin Med Insights Arthritis Musculoskelet Disord. 2011. PMID: 21792344 Free PMC article.
560 results