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19,323 results
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Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3.
Seth RB, Sun L, Ea CK, Chen ZJ. Seth RB, et al. Among authors: sun l. Cell. 2005 Sep 9;122(5):669-82. doi: 10.1016/j.cell.2005.08.012. Cell. 2005. PMID: 16125763
Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing.
Chen Q, Sun L, Chen ZJ. Chen Q, et al. Among authors: sun l. Nat Immunol. 2016 Sep 20;17(10):1142-9. doi: 10.1038/ni.3558. Nat Immunol. 2016. PMID: 27648547 Review.
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response.
Hou F, Sun L, Zheng H, Skaug B, Jiang QX, Chen ZJ. Hou F, et al. Among authors: sun l. Cell. 2011 Aug 5;146(3):448-61. doi: 10.1016/j.cell.2011.06.041. Epub 2011 Jul 21. Cell. 2011. PMID: 21782231 Free PMC article.
T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20.
Coornaert B, Baens M, Heyninck K, Bekaert T, Haegman M, Staal J, Sun L, Chen ZJ, Marynen P, Beyaert R. Coornaert B, et al. Among authors: sun l. Nat Immunol. 2008 Mar;9(3):263-71. doi: 10.1038/ni1561. Epub 2008 Jan 27. Nat Immunol. 2008. PMID: 18223652
NLRX1 is a regulator of mitochondrial antiviral immunity.
Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmermann AG, Accavitti-Loper MA, Madden VJ, Sun L, Ye Z, Lich JD, Heise MT, Chen Z, Ting JP. Moore CB, et al. Among authors: sun l. Nature. 2008 Jan 31;451(7178):573-7. doi: 10.1038/nature06501. Epub 2008 Jan 16. Nature. 2008. PMID: 18200010
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity.
Gack MU, Shin YC, Joo CH, Urano T, Liang C, Sun L, Takeuchi O, Akira S, Chen Z, Inoue S, Jung JU. Gack MU, et al. Among authors: sun l. Nature. 2007 Apr 19;446(7138):916-920. doi: 10.1038/nature05732. Nature. 2007. PMID: 17392790
Antiviral innate immunity pathways.
Seth RB, Sun L, Chen ZJ. Seth RB, et al. Among authors: sun l. Cell Res. 2006 Feb;16(2):141-7. doi: 10.1038/ Cell Res. 2006. PMID: 16474426 Review.
The specific and essential role of MAVS in antiviral innate immune responses.
Sun Q, Sun L, Liu HH, Chen X, Seth RB, Forman J, Chen ZJ. Sun Q, et al. Among authors: sun l. Immunity. 2006 May;24(5):633-42. doi: 10.1016/j.immuni.2006.04.004. Immunity. 2006. PMID: 16713980
Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses.
Gao D, Wu J, Wu YT, Du F, Aroh C, Yan N, Sun L, Chen ZJ. Gao D, et al. Among authors: sun l. Science. 2013 Aug 23;341(6148):903-6. doi: 10.1126/science.1240933. Epub 2013 Aug 8. Science. 2013. PMID: 23929945 Free PMC article.
Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids.
Tan X, Sun L, Chen J, Chen ZJ. Tan X, et al. Among authors: sun l. Annu Rev Microbiol. 2018 Sep 8;72:447-478. doi: 10.1146/annurev-micro-102215-095605. Annu Rev Microbiol. 2018. PMID: 30200854 Review.
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