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Endothelial cells promote triple-negative breast cancer cell metastasis via PAI-1 and CCL5 signaling.
Zhang W, Xu J, Fang H, Tang L, Chen W, Sun Q, Zhang Q, Yang F, Sun Z, Cao L, Wang Y, Guan X. Zhang W, et al. Among authors: sun q, sun z. FASEB J. 2018 Jan;32(1):276-288. doi: 10.1096/fj.201700237RR. Epub 2017 Sep 12. FASEB J. 2018. PMID: 28899878
Taken together, our results suggest that ECs enhance EMT-induced TNBC cell metastasis via PAI-1 and CCL5 signaling and illustrate the potential of developing new PAI-1- and CCL5-targeting therapy for patients with TNBC.-Zhang, W., Xu, J., Fang, H., Tang, L., Chen, W., Sun, …
Taken together, our results suggest that ECs enhance EMT-induced TNBC cell metastasis via PAI-1 and CCL5 signaling and illustrate the potent …
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