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Integrase-defective lentiviral vectors encoding cytokines induce differentiation of human dendritic cells and stimulate multivalent immune responses in vitro and in vivo.
Daenthanasanmak A, Salguero G, Borchers S, Figueiredo C, Jacobs R, Sundarasetty BS, Schneider A, Schambach A, Eiz-Vesper B, Blasczyk R, Weissinger EM, Ganser A, Stripecke R. Daenthanasanmak A, et al. Among authors: sundarasetty bs. Vaccine. 2012 Jul 20;30(34):5118-31. doi: 10.1016/j.vaccine.2012.05.063. Epub 2012 Jun 9. Vaccine. 2012. PMID: 22691433 Free article.
Monocytes transduced with lentiviral vectors expressing hepatitis C virus non-structural proteins and differentiated into dendritic cells stimulate multi-antigenic CD8(+) T cell responses.
Jirmo AC, Koya RC, Sundarasetty BS, Pincha M, Yu GY, Lai M, Bakshi R, Schlaphoff V, Grabowski J, Behrens G, Wedemeyer H, Stripecke R. Jirmo AC, et al. Among authors: sundarasetty bs. Vaccine. 2010 Jan 22;28(4):922-33. doi: 10.1016/j.vaccine.2009.10.150. Epub 2009 Nov 18. Vaccine. 2010. PMID: 19931383
Lentiviral vectors for immunization: an inflammatory field.
Pincha M, Sundarasetty BS, Stripecke R. Pincha M, et al. Among authors: sundarasetty bs. Expert Rev Vaccines. 2010 Mar;9(3):309-21. doi: 10.1586/erv.10.9. Expert Rev Vaccines. 2010. PMID: 20218859 Review.
Preconditioning therapy with lentiviral vector-programmed dendritic cells accelerates the homeostatic expansion of antigen-reactive human T cells in NOD.Rag1-/-.IL-2rγc-/- mice.
Salguero G, Sundarasetty BS, Borchers S, Wedekind D, Eiz-Vesper B, Velaga S, Jirmo AC, Behrens G, Warnecke G, Knöfel AK, Blasczyk R, Mischak-Weissinger E, Ganser A, Stripecke R. Salguero G, et al. Among authors: sundarasetty bs. Hum Gene Ther. 2011 Oct;22(10):1209-24. doi: 10.1089/hum.2010.215. Epub 2011 Jul 27. Hum Gene Ther. 2011. PMID: 21574869 Free PMC article.
Identity, potency, in vivo viability, and scaling up production of lentiviral vector-induced dendritic cells for melanoma immunotherapy.
Pincha M, Sundarasetty BS, Salguero G, Gutzmer R, Garritsen H, Macke L, Schneider A, Lenz D, Figueiredo C, Blasczyk R, Ruggiero E, Schmidt M, von Kalle C, Puff C, Modlich U, von der Leyen H, Wicke DC, Ganser A, Stripecke R. Pincha M, et al. Among authors: sundarasetty bs. Hum Gene Ther Methods. 2012 Feb;23(1):38-55. doi: 10.1089/hgtb.2011.170. Hum Gene Ther Methods. 2012. PMID: 22428979
Dendritic cell-mediated immune humanization of mice: implications for allogeneic and xenogeneic stem cell transplantation.
Salguero G, Daenthanasanmak A, Münz C, Raykova A, Guzmán CA, Riese P, Figueiredo C, Länger F, Schneider A, Macke L, Sundarasetty BS, Witte T, Ganser A, Stripecke R. Salguero G, et al. Among authors: sundarasetty bs. J Immunol. 2014 May 15;192(10):4636-47. doi: 10.4049/jimmunol.1302887. Epub 2014 Apr 16. J Immunol. 2014. PMID: 24740501 Clinical Trial.
Generation of lentivirus-induced dendritic cells under GMP-compliant conditions for adaptive immune reconstitution against cytomegalovirus after stem cell transplantation.
Sundarasetty BS, Kloess S, Oberschmidt O, Naundorf S, Kuehlcke K, Daenthanasanmak A, Gerasch L, Figueiredo C, Blasczyk R, Ruggiero E, Fronza R, Schmidt M, von Kalle C, Rothe M, Ganser A, Koehl U, Stripecke R. Sundarasetty BS, et al. J Transl Med. 2015 Jul 22;13:240. doi: 10.1186/s12967-015-0599-5. J Transl Med. 2015. PMID: 26198406 Free PMC article.
Human Effector Memory T Helper Cells Engage with Mouse Macrophages and Cause Graft-versus-Host-Like Pathology in Skin of Humanized Mice Used in a Nonclinical Immunization Study.
Sundarasetty B, Volk V, Theobald SJ, Rittinghausen S, Schaudien D, Neuhaus V, Figueiredo C, Schneider A, Gerasch L, Mucci A, Moritz T, von Kaisenberg C, Spineli LM, Sewald K, Braun A, Weigt H, Ganser A, Stripecke R. Sundarasetty B, et al. Am J Pathol. 2017 Jun;187(6):1380-1398. doi: 10.1016/j.ajpath.2017.02.015. Epub 2017 Apr 20. Am J Pathol. 2017. PMID: 28432872 Free article.
16 results