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Non-cognitive behaviours in an APP/PS1 transgenic model of Alzheimer's disease.
Pugh PL, Richardson JC, Bate ST, Upton N, Sunter D. Pugh PL, et al. Among authors: sunter d. Behav Brain Res. 2007 Mar 12;178(1):18-28. doi: 10.1016/j.bbr.2006.11.044. Epub 2007 Jan 16. Behav Brain Res. 2007. PMID: 17229472
Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes.
Pugh PL, Vidgeon-Hart MP, Ashmeade T, Culbert AA, Seymour Z, Perren MJ, Joyce F, Bate ST, Babin A, Virley DJ, Richardson JC, Upton N, Sunter D. Pugh PL, et al. Among authors: sunter d. J Neuroinflammation. 2007 Feb 26;4:8. doi: 10.1186/1742-2094-4-8. J Neuroinflammation. 2007. PMID: 17324270 Free PMC article.
SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models.
Hirst WD, Stean TO, Rogers DC, Sunter D, Pugh P, Moss SF, Bromidge SM, Riley G, Smith DR, Bartlett S, Heidbreder CA, Atkins AR, Lacroix LP, Dawson LA, Foley AG, Regan CM, Upton N. Hirst WD, et al. Among authors: sunter d. Eur J Pharmacol. 2006 Dec 28;553(1-3):109-19. doi: 10.1016/j.ejphar.2006.09.049. Epub 2006 Sep 29. Eur J Pharmacol. 2006. PMID: 17069795
., b.i.d. for 7 days) significantly reversed a scopolamine-induced deficit (0.5 mg/kg i.p.) in a rat novel object recognition paradigm. Moreover, in aged rats (22 months old) SB-399885 (10 mg/kg p.o., b.i.d. for 7 days) fully reversed the age-dependent deficit in wa …
., b.i.d. for 7 days) significantly reversed a scopolamine-induced deficit (0.5 mg/kg i.p.) in a rat novel object recognition paradig …
Chronic treatment with the α2-adrenoceptor antagonist fluparoxan prevents age-related deficits in spatial working memory in APP×PS1 transgenic mice without altering β-amyloid plaque load or astrocytosis.
Scullion GA, Kendall DA, Marsden CA, Sunter D, Pardon MC. Scullion GA, et al. Among authors: sunter d. Neuropharmacology. 2011 Feb-Mar;60(2-3):223-34. doi: 10.1016/j.neuropharm.2010.09.002. Epub 2010 Sep 17. Neuropharmacology. 2011. PMID: 20850464
Orexins: effects on behavior and localisation of orexin receptor 2 messenger ribonucleic acid in the rat brainstem.
Sunter D, Morgan I, Edwards CM, Dakin CL, Murphy KG, Gardiner J, Taheri S, Rayes E, Bloom SR. Sunter D, et al. Brain Res. 2001 Jul 13;907(1-2):27-34. doi: 10.1016/s0006-8993(01)02344-7. Brain Res. 2001. PMID: 11430882
Central noradrenergic depletion by DSP-4 prevents stress-induced memory impairments in the object recognition task.
Scullion GA, Kendall DA, Sunter D, Marsden CA, Pardon MC. Scullion GA, et al. Among authors: sunter d. Neuroscience. 2009 Dec 1;164(2):415-23. doi: 10.1016/j.neuroscience.2009.08.046. Epub 2009 Aug 29. Neuroscience. 2009. PMID: 19720115
New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord.
Jane DE, Pittaway K, Sunter DC, Thomas NK, Watkins JC. Jane DE, et al. Among authors: sunter dc. Neuropharmacology. 1995 Aug;34(8):851-6. doi: 10.1016/0028-3908(95)00063-c. Neuropharmacology. 1995. PMID: 8532166
Stereospecific antagonism by (+)-alpha-methyl-4-carboxyphenylglycine (MCPG) of (1S,3R)-ACPD-induced effects in neonatal rat motoneurones and rat thalamic neurones.
Jane DE, Jones PL, Pook PC, Salt TE, Sunter DC, Watkins JC. Jane DE, et al. Among authors: sunter dc. Neuropharmacology. 1993 Jul;32(7):725-7. doi: 10.1016/0028-3908(93)90088-k. Neuropharmacology. 1993. PMID: 7689710
. (+)-MCPG preferentially reduced (1S,3R)-ACPD-induced responses relative to responses induced by (S)-alpha-amino-3-hydorxy-5-methylisoxazole-4-propionic acid (AMPA) and N-methyl-D-aspartate (NMDA)....
. (+)-MCPG preferentially reduced (1S,3R)-ACPD-induced responses relative to responses induced by (S)-alpha-amino-3-hydorxy-5-methylisoxazol …
Differential actions of 3-(4-chlorophenyl) glutamic acid stereoisomers and L-trans-pyrrolidine-2,4-dicarboxylic acid upon L-homocysteic acid- and L-glutamic acid-induced responses from rat spinal motoneurones.
Chalmers DJ, Jane DE, Sunter DC, Thompson GA, Udvarhelyi PM, Kilpatrick IC, Watkins JC. Chalmers DJ, et al. Among authors: sunter dc. Neuropharmacology. 1995 Dec;34(12):1589-95. doi: 10.1016/0028-3908(95)00124-7. Neuropharmacology. 1995. PMID: 8788956
The (2R,3S)- isomer had a slight but significant depressant action which could be attributed to N-methyl-D-aspartate (NMDA) receptor antagonism. ...
The (2R,3S)- isomer had a slight but significant depressant action which could be attributed to N-methyl-D-aspartate (NMDA) receptor …
Intracerebroventricular injection of apelin-13 reduces food intake in the rat.
Sunter D, Hewson AK, Dickson SL. Sunter D, et al. Neurosci Lett. 2003 Dec 15;353(1):1-4. doi: 10.1016/s0304-3940(03)00351-3. Neurosci Lett. 2003. PMID: 14642423
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