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172 results
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A limited role for balancing selection.
Asthana S, Schmidt S, Sunyaev S. Asthana S, et al. Among authors: sunyaev s. Trends Genet. 2005 Jan;21(1):30-2. doi: 10.1016/j.tig.2004.11.001. Trends Genet. 2005. PMID: 15680511
Towards a structural basis of human non-synonymous single nucleotide polymorphisms.
Sunyaev S, Ramensky V, Bork P. Sunyaev S, et al. Trends Genet. 2000 May;16(5):198-200. doi: 10.1016/s0168-9525(00)01988-0. Trends Genet. 2000. PMID: 10782110 Review. No abstract available.
SNP frequencies in human genes an excess of rare alleles and differing modes of selection.
Sunyaev SR, Lathe WC 3rd, Ramensky VE, Bork P. Sunyaev SR, et al. Trends Genet. 2000 Aug;16(8):335-7. doi: 10.1016/s0168-9525(00)02058-8. Trends Genet. 2000. PMID: 10904261 No abstract available.
Increase of functional diversity by alternative splicing.
Kriventseva EV, Koch I, Apweiler R, Vingron M, Bork P, Gelfand MS, Sunyaev S. Kriventseva EV, et al. Among authors: sunyaev s. Trends Genet. 2003 Mar;19(3):124-8. doi: 10.1016/S0168-9525(03)00023-4. Trends Genet. 2003. PMID: 12615003 Review.
Impact of selection, mutation rate and genetic drift on human genetic variation.
Sunyaev S, Kondrashov FA, Bork P, Ramensky V. Sunyaev S, et al. Hum Mol Genet. 2003 Dec 15;12(24):3325-30. doi: 10.1093/hmg/ddg359. Epub 2003 Oct 21. Hum Mol Genet. 2003. PMID: 14570704
Small fitness effect of mutations in highly conserved non-coding regions.
Kryukov GV, Schmidt S, Sunyaev S. Kryukov GV, et al. Among authors: sunyaev s. Hum Mol Genet. 2005 Aug 1;14(15):2221-9. doi: 10.1093/hmg/ddi226. Epub 2005 Jun 30. Hum Mol Genet. 2005. PMID: 15994173
Most rare missense alleles are deleterious in humans: implications for complex disease and association studies.
Kryukov GV, Pennacchio LA, Sunyaev SR. Kryukov GV, et al. Am J Hum Genet. 2007 Apr;80(4):727-39. doi: 10.1086/513473. Epub 2007 Mar 8. Am J Hum Genet. 2007. PMID: 17357078 Free PMC article.
Widely distributed noncoding purifying selection in the human genome.
Asthana S, Noble WS, Kryukov G, Grant CE, Sunyaev S, Stamatoyannopoulos JA. Asthana S, et al. Among authors: sunyaev s. Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12410-5. doi: 10.1073/pnas.0705140104. Epub 2007 Jul 17. Proc Natl Acad Sci U S A. 2007. PMID: 17640883 Free PMC article.
Common single-nucleotide polymorphisms act in concert to affect plasma levels of high-density lipoprotein cholesterol.
Spirin V, Schmidt S, Pertsemlidis A, Cooper RS, Cohen JC, Sunyaev SR. Spirin V, et al. Among authors: sunyaev sr. Am J Hum Genet. 2007 Dec;81(6):1298-303. doi: 10.1086/522497. Am J Hum Genet. 2007. PMID: 17952847 Free PMC article.
Analysis of sequence conservation at nucleotide resolution.
Asthana S, Roytberg M, Stamatoyannopoulos J, Sunyaev S. Asthana S, et al. Among authors: sunyaev s. PLoS Comput Biol. 2007 Dec;3(12):e254. doi: 10.1371/journal.pcbi.0030254. Epub 2007 Nov 14. PLoS Comput Biol. 2007. PMID: 18166073 Free PMC article.
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