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508 results

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Page 1
Bacteriophage host range and bacterial resistance.
Hyman P, Abedon ST. Hyman P, et al. Adv Appl Microbiol. 2010;70:217-48. doi: 10.1016/S0065-2164(10)70007-1. Epub 2010 Mar 6. Adv Appl Microbiol. 2010. PMID: 20359459 Review.
We consider these adaptations as they occur among bacteriophages (phages) and their bacterial hosts, since they are significant to phage use as antibacterials (phage therapy) or to protection of industrial ferments from phage attack. ...Restrict …
We consider these adaptations as they occur among bacteriophages (phages) and their bacterial hosts, since they are significan …
Intestinal phages interact with bacteria and are involved in human diseases.
Shuwen H, Kefeng D. Shuwen H, et al. Gut Microbes. 2022 Jan-Dec;14(1):2113717. doi: 10.1080/19490976.2022.2113717. Gut Microbes. 2022. PMID: 36037202 Free PMC article. Review.
EMBL-EBI The European Bioinformatics Institute; E. coli Escherichia coli; E. faecalis Enterobacter faecalis; B. fragilis Bacteroides fragilis; B. vulgatus Bacteroides vulgatus; SaPIs Staphylococcus aureus pathogenicity islands; ARGs Antibiotic resistance genes; STEC Shiga toxigen …
EMBL-EBI The European Bioinformatics Institute; E. coli Escherichia coli; E. faecalis Enterobacter faecalis; B. fragilis Bacteroides fragili …
Bacteriophage secondary infection.
Abedon ST. Abedon ST. Virol Sin. 2015 Feb;30(1):3-10. doi: 10.1007/s12250-014-3547-2. Epub 2015 Jan 13. Virol Sin. 2015. PMID: 25595214 Free PMC article. Review.
The phrase secondary infection also may be used equivalently to superinfection or coinfection, with each of these terms borrowed from medical microbiology, and can result in genetic exchange between phages, phage-on-phage parasitism, and various partia …
The phrase secondary infection also may be used equivalently to superinfection or coinfection, with each of these terms borrowed from …
Bacteriophage P22 SieA-mediated superinfection exclusion.
Leavitt JC, Woodbury BM, Gilcrease EB, Bridges CM, Teschke CM, Casjens SR. Leavitt JC, et al. mBio. 2024 Feb 14;15(2):e0216923. doi: 10.1128/mbio.02169-23. Epub 2024 Jan 18. mBio. 2024. PMID: 38236051 Free PMC article.
Many temperate phages encode prophage-expressed functions that interfere with superinfection of the host bacterium by external phages. ...This report is the first to describe the mechanism by which bacteriophage P22 SieA superinfection exclusion …
Many temperate phages encode prophage-expressed functions that interfere with superinfection of the host bacterium by external …
Structural basis for host recognition and superinfection exclusion by bacteriophage T5.
van den Berg B, Silale A, Baslé A, Brandner AF, Mader SL, Khalid S. van den Berg B, et al. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2211672119. doi: 10.1073/pnas.2211672119. Epub 2022 Oct 10. Proc Natl Acad Sci U S A. 2022. PMID: 36215462 Free PMC article.
A key but poorly understood stage of the bacteriophage life cycle is the binding of phage receptor-binding proteins (RBPs) to receptors on the host cell surface, leading to injection of the phage genome and, for lytic phages, host cell lysis. To preven …
A key but poorly understood stage of the bacteriophage life cycle is the binding of phage receptor-binding proteins (RBPs) to …
Phage against the Machine: The SIE-ence of Superinfection Exclusion.
Bucher MJ, Czyż DM. Bucher MJ, et al. Viruses. 2024 Aug 23;16(9):1348. doi: 10.3390/v16091348. Viruses. 2024. PMID: 39339825 Free PMC article. Review.
Prophages can alter their bacterial hosts to prevent other phages from infecting the same cell, a mechanism known as superinfection exclusion (SIE). ...Therefore, the impact of SIE extends beyond the immediate defense against superinfection, influencing the o …
Prophages can alter their bacterial hosts to prevent other phages from infecting the same cell, a mechanism known as superinfectio
Bacteriophage tRNA-dependent lysogeny: requirement of phage-encoded tRNA genes for establishment of lysogeny.
Guerrero-Bustamante CA, Hatfull GF. Guerrero-Bustamante CA, et al. mBio. 2024 Feb 14;15(2):e0326023. doi: 10.1128/mbio.03260-23. Epub 2024 Jan 18. mBio. 2024. PMID: 38236026 Free PMC article.
Bacteriophages are large and diverse components of the biosphere, and many phages are temperate. ...Here, we show that phage-encoded tRNAs play key roles in the establishment of lysogeny of some temperate phages. ...
Bacteriophages are large and diverse components of the biosphere, and many phages are temperate. ...Here, we show that phag
Unveil the Secret of the Bacteria and Phage Arms Race.
Wang Y, Fan H, Tong Y. Wang Y, et al. Int J Mol Sci. 2023 Feb 22;24(5):4363. doi: 10.3390/ijms24054363. Int J Mol Sci. 2023. PMID: 36901793 Free PMC article. Review.
Bacteria have developed different mechanisms to defend against phages, such as preventing phages from being adsorbed on the surface of host bacteria; through the superinfection exclusion (Sie) block of phage's nucleic acid injection; by restrict …
Bacteria have developed different mechanisms to defend against phages, such as preventing phages from being adsorbed on the su …
A game of resistance: War between bacteria and phages and how phage cocktails can be the solution.
Costa P, Pereira C, Romalde JL, Almeida A. Costa P, et al. Virology. 2024 Nov;599:110209. doi: 10.1016/j.virol.2024.110209. Epub 2024 Aug 15. Virology. 2024. PMID: 39186863 Free article. Review.
While phages hold promise as an antibiotic alternative, they encounter significant challenges in combating bacterial infections, primarily due to the emergence of phage-resistant bacteria. Bacterial defence mechanisms like superinfection exclusion, CRISPR, an …
While phages hold promise as an antibiotic alternative, they encounter significant challenges in combating bacterial infections, prim …
Filamentous prophage capsid proteins contribute to superinfection exclusion and phage defence in Pseudomonas aeruginosa.
Wang W, Li Y, Tang K, Lin J, Gao X, Guo Y, Wang X. Wang W, et al. Environ Microbiol. 2022 Sep;24(9):4285-4298. doi: 10.1111/1462-2920.15991. Epub 2022 Apr 11. Environ Microbiol. 2022. PMID: 35384225
Filamentous prophages in Pseudomonas aeruginosa PAO1 are converted to superinfective phage virions during biofilm development. Superinfection exclusion is necessary for the development of resistance against superinfective phage virions in host cells. ...The m …
Filamentous prophages in Pseudomonas aeruginosa PAO1 are converted to superinfective phage virions during biofilm development. Sup
508 results