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The following terms were not found in PubMed: machine+suppression+Chloroquine+nigella, sativa+parasitaemia+plasmodium
Page 1
Host sphingolipids support Plasmodium berghei liver stage development.
Schroeder EA, Colón IC, Petruzziello PE, Derbyshire ER. Schroeder EA, et al. mBio. 2025 Aug 13;16(8):e0167525. doi: 10.1128/mbio.01675-25. Epub 2025 Jul 21. mBio. 2025. PMID: 40689642 Free PMC article.
Live microscopy studies using NBD labeled sphingolipids further found that exogenous lipids are actively transported into the PV with sphingolipid scavenging occurring at all tested time points throughout the liver stage. This was, in part, supported by the host ceramide t …
Live microscopy studies using NBD labeled sphingolipids further found that exogenous lipids are actively transported into the PV with sphing …
Transfection of malaria parasites.
Waters AP, Thomas AW, van Dijk MR, Janse CJ. Waters AP, et al. Methods. 1997 Oct;13(2):134-47. doi: 10.1006/meth.1997.0506. Methods. 1997. PMID: 9405197
The stable genetic transformation of three phylogenetically diverse species of Plasmodium, the parasitic etiological agent of malaria, is now possible. ...We describe here the methods for propagation of the two animal models (Plasmodium berghei and Plasmodium knowle …
The stable genetic transformation of three phylogenetically diverse species of Plasmodium, the parasitic etiological agent of malaria …
Division and Transmission: Malaria Parasite Development in the Mosquito.
Guttery DS, Zeeshan M, Ferguson DJP, Holder AA, Tewari R. Guttery DS, et al. Annu Rev Microbiol. 2022 Sep 8;76:113-134. doi: 10.1146/annurev-micro-041320-010046. Epub 2022 May 24. Annu Rev Microbiol. 2022. PMID: 35609946 Review.
The malaria parasite life cycle alternates between two hosts: a vertebrate and the female Anopheles mosquito vector. Cell division, proliferation, and invasion are essential for parasite development, transmission, and survival. ...We also emphasize the still-unanswered imp …
The malaria parasite life cycle alternates between two hosts: a vertebrate and the female Anopheles mosquito vector. Cell division, p …
Mosquito immune defenses against Plasmodium infection.
Cirimotich CM, Dong Y, Garver LS, Sim S, Dimopoulos G. Cirimotich CM, et al. Dev Comp Immunol. 2010 Apr;34(4):387-95. doi: 10.1016/j.dci.2009.12.005. Epub 2009 Dec 23. Dev Comp Immunol. 2010. PMID: 20026176 Free PMC article. Review.
The causative agent of malaria, Plasmodium, has to undergo complex developmental transitions and survive attacks from the mosquito's innate immune system to achieve transmission from one host to another through the vector. Here we discuss recent findings on the role of the …
The causative agent of malaria, Plasmodium, has to undergo complex developmental transitions and survive attacks from the mosquito's innate …
Combining transgenesis with paratransgenesis to fight malaria.
Huang W, Vega-Rodriguez J, Kizito C, Cha SJ, Jacobs-Lorena M. Huang W, et al. Elife. 2022 Oct 25;11:e77584. doi: 10.7554/eLife.77584. Elife. 2022. PMID: 36281969 Free PMC article.
Malaria is among the deadliest infectious diseases, and Plasmodium, the causative agent, needs to complete a complex development cycle in its vector mosquito for transmission to occur. Two promising strategies to curb transmission are transgenesis, consisting of geneticall …
Malaria is among the deadliest infectious diseases, and Plasmodium, the causative agent, needs to complete a complex development cycle in it …
Anopheles Midgut FREP1 Mediates Plasmodium Invasion.
Zhang G, Niu G, Franca CM, Dong Y, Wang X, Butler NS, Dimopoulos G, Li J. Zhang G, et al. J Biol Chem. 2015 Jul 3;290(27):16490-501. doi: 10.1074/jbc.M114.623165. Epub 2015 May 19. J Biol Chem. 2015. PMID: 25991725 Free PMC article.
However, the molecular mechanisms of Plasmodium invasion of mosquito midguts have not been fully elucidated. Previously, we showed that genetic polymorphisms in the fibrinogen-related protein 1 (FREP1) gene are significantly associated with Plasmodium falciparum infection …
However, the molecular mechanisms of Plasmodium invasion of mosquito midguts have not been fully elucidated. Previously, we showed that g …
Plasmodium berghei oocysts possess fatty acid synthesis and scavenging routes.
Saeed S, Tremp AZ, Dessens JT. Saeed S, et al. Sci Rep. 2023 Aug 5;13(1):12700. doi: 10.1038/s41598-023-39708-z. Sci Rep. 2023. PMID: 37543672 Free PMC article.
In the mosquito, P. falciparum oocysts express and rely on FAS enzymes for sporozoite formation, but P. yoelii oocysts do not express, nor depend on, FAS enzymes and thus rely on FA scavenging to support sporogony. In P. berghei, FAS enzymes are similarly expendable …
In the mosquito, P. falciparum oocysts express and rely on FAS enzymes for sporozoite formation, but P. yoelii oocysts do not express, nor d …
Transport of antibody into the skin is only partially dependent upon the neonatal Fc-receptor.
Nasir G, Sinnis P. Nasir G, et al. PLoS One. 2023 Apr 24;18(4):e0273960. doi: 10.1371/journal.pone.0273960. eCollection 2023. PLoS One. 2023. PMID: 37093800 Free PMC article.
The dermis is the portal of entry for most vector-transmitted pathogens, making the host's immune response at this site critical in mitigating the magnitude of infection. ...These findings have implications for the rational design of antibody-based therapeutics for malaria …
The dermis is the portal of entry for most vector-transmitted pathogens, making the host's immune response at this site critical in m …
Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei.
Das S, Unhale T, Marinach C, Valeriano Alegria BDC, Roux C, Madry H, Mohand Oumoussa B, Amino R, Iwanaga S, Briquet S, Silvie O. Das S, et al. Sci Rep. 2025 Jan 23;15(1):2949. doi: 10.1038/s41598-025-87114-4. Sci Rep. 2025. PMID: 39849074 Free PMC article.
The parasite has a highly adaptable life cycle comprising successive rounds of asexual replication in a vertebrate host and sexual maturation in the mosquito vector Anopheles. Genetic manipulation of the parasite has been instrumental for deciphering the function of …
The parasite has a highly adaptable life cycle comprising successive rounds of asexual replication in a vertebrate host and sexual maturatio …
Imaging Infection by Vector-Borne Protozoan Parasites Using Whole-Mouse Bioluminescence.
Sá M, Costa DM, Tavares J. Sá M, et al. Methods Mol Biol. 2022;2524:353-367. doi: 10.1007/978-1-0716-2453-1_29. Methods Mol Biol. 2022. PMID: 35821487
Vector-borne protozoan parasites such as Plasmodium spp. Leishmania spp. and Trypanosoma brucei are responsible for several serious diseases. ...This chapter focuses on the methods that utilize whole-mouse BLI to (i) evaluate the homing and infectivity of Plasmodium ber …
Vector-borne protozoan parasites such as Plasmodium spp. Leishmania spp. and Trypanosoma brucei are responsible for several serious d …
551 results