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The following terms were not found in PubMed: machine+suppression+Chloroquine+nigella, sativa+parasitaemia+plasmodium
Page 1
Host sphingolipids support Plasmodium berghei liver stage development.
Schroeder EA, Colón IC, Petruzziello PE, Derbyshire ER. Schroeder EA, et al. mBio. 2025 Aug 13;16(8):e0167525. doi: 10.1128/mbio.01675-25. Epub 2025 Jul 21. mBio. 2025. PMID: 40689642 Free PMC article.
Live microscopy studies using NBD labeled sphingolipids further found that exogenous lipids are actively transported into the PV with sphingolipid scavenging occurring at all tested time points throughout the liver stage. This was, in part, supported by the host ceramide t …
Live microscopy studies using NBD labeled sphingolipids further found that exogenous lipids are actively transported into the PV with sphing …
Division and Transmission: Malaria Parasite Development in the Mosquito.
Guttery DS, Zeeshan M, Ferguson DJP, Holder AA, Tewari R. Guttery DS, et al. Annu Rev Microbiol. 2022 Sep 8;76:113-134. doi: 10.1146/annurev-micro-041320-010046. Epub 2022 May 24. Annu Rev Microbiol. 2022. PMID: 35609946 Review.
The malaria parasite life cycle alternates between two hosts: a vertebrate and the female Anopheles mosquito vector. Cell division, proliferation, and invasion are essential for parasite development, transmission, and survival. ...We also emphasize the still-unanswered imp …
The malaria parasite life cycle alternates between two hosts: a vertebrate and the female Anopheles mosquito vector. Cell division, p …
Transfection of malaria parasites.
Waters AP, Thomas AW, van Dijk MR, Janse CJ. Waters AP, et al. Methods. 1997 Oct;13(2):134-47. doi: 10.1006/meth.1997.0506. Methods. 1997. PMID: 9405197
The stable genetic transformation of three phylogenetically diverse species of Plasmodium, the parasitic etiological agent of malaria, is now possible. ...We describe here the methods for propagation of the two animal models (Plasmodium berghei and Plasmodium knowle …
The stable genetic transformation of three phylogenetically diverse species of Plasmodium, the parasitic etiological agent of malaria …
Plasmodium berghei oocysts possess fatty acid synthesis and scavenging routes.
Saeed S, Tremp AZ, Dessens JT. Saeed S, et al. Sci Rep. 2023 Aug 5;13(1):12700. doi: 10.1038/s41598-023-39708-z. Sci Rep. 2023. PMID: 37543672 Free PMC article.
In the mosquito, P. falciparum oocysts express and rely on FAS enzymes for sporozoite formation, but P. yoelii oocysts do not express, nor depend on, FAS enzymes and thus rely on FA scavenging to support sporogony. In P. berghei, FAS enzymes are similarly expendable …
In the mosquito, P. falciparum oocysts express and rely on FAS enzymes for sporozoite formation, but P. yoelii oocysts do not express, nor d …
Mosquito immune defenses against Plasmodium infection.
Cirimotich CM, Dong Y, Garver LS, Sim S, Dimopoulos G. Cirimotich CM, et al. Dev Comp Immunol. 2010 Apr;34(4):387-95. doi: 10.1016/j.dci.2009.12.005. Epub 2009 Dec 23. Dev Comp Immunol. 2010. PMID: 20026176 Free PMC article. Review.
The causative agent of malaria, Plasmodium, has to undergo complex developmental transitions and survive attacks from the mosquito's innate immune system to achieve transmission from one host to another through the vector. Here we discuss recent findings on the role of the …
The causative agent of malaria, Plasmodium, has to undergo complex developmental transitions and survive attacks from the mosquito's innate …
Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei.
Das S, Unhale T, Marinach C, Valeriano Alegria BDC, Roux C, Madry H, Mohand Oumoussa B, Amino R, Iwanaga S, Briquet S, Silvie O. Das S, et al. Sci Rep. 2025 Jan 23;15(1):2949. doi: 10.1038/s41598-025-87114-4. Sci Rep. 2025. PMID: 39849074 Free PMC article.
The parasite has a highly adaptable life cycle comprising successive rounds of asexual replication in a vertebrate host and sexual maturation in the mosquito vector Anopheles. Genetic manipulation of the parasite has been instrumental for deciphering the function of …
The parasite has a highly adaptable life cycle comprising successive rounds of asexual replication in a vertebrate host and sexual maturatio …
Combining transgenesis with paratransgenesis to fight malaria.
Huang W, Vega-Rodriguez J, Kizito C, Cha SJ, Jacobs-Lorena M. Huang W, et al. Elife. 2022 Oct 25;11:e77584. doi: 10.7554/eLife.77584. Elife. 2022. PMID: 36281969 Free PMC article.
Malaria is among the deadliest infectious diseases, and Plasmodium, the causative agent, needs to complete a complex development cycle in its vector mosquito for transmission to occur. Two promising strategies to curb transmission are transgenesis, consisting of geneticall …
Malaria is among the deadliest infectious diseases, and Plasmodium, the causative agent, needs to complete a complex development cycle in it …
A Comprehensive Gender-related Secretome of Plasmodium berghei Sexual Stages.
Grasso F, Mochi S, Fratini F, Olivieri A, Currà C, Siden Kiamos I, Deligianni E, Birago C, Picci L, Pizzi E, Pace T, Ponzi M. Grasso F, et al. Mol Cell Proteomics. 2020 Dec;19(12):1986-1997. doi: 10.1074/mcp.RA120.002212. Epub 2020 Sep 3. Mol Cell Proteomics. 2020. PMID: 32883804 Free PMC article.
Sexual stage maturation occurs in the midgut of the mosquito vector, where male and female gametes egress from the host erythrocytes to fuse and form a zygote. ...In this study, we used the rodent model parasite Plasmodium berghei to design a label-free quantitative …
Sexual stage maturation occurs in the midgut of the mosquito vector, where male and female gametes egress from the host erythrocytes …
The private life of malaria parasites: Strategies for sexual reproduction.
Schneider P, Reece SE. Schneider P, et al. Mol Biochem Parasitol. 2021 Jul;244:111375. doi: 10.1016/j.molbiopara.2021.111375. Epub 2021 May 20. Mol Biochem Parasitol. 2021. PMID: 34023299 Free PMC article. Review.
Malaria parasites exhibit a complex lifecycle, requiring extensive asexual replication in the liver and blood of the vertebrate host, and in the haemocoel of the insect vector. Yet, they must also undergo a single round of sexual reproduction, which occurs in the vector …
Malaria parasites exhibit a complex lifecycle, requiring extensive asexual replication in the liver and blood of the vertebrate host, and in …
Regulation of sexual commitment in malaria parasites - a complex affair.
Voss TS, Brancucci NM. Voss TS, et al. Curr Opin Microbiol. 2024 Jun;79:102469. doi: 10.1016/j.mib.2024.102469. Epub 2024 Apr 4. Curr Opin Microbiol. 2024. PMID: 38574448 Free article. Review.
Depending on the state of infection, either path may support or impair the ultimate goal of human-to-human transmission via the mosquito vector. ...Recent work provided fascinating molecular insight into shared and unique mechanisms underlying the control and enviro …
Depending on the state of infection, either path may support or impair the ultimate goal of human-to-human transmission via the mosqu …
548 results