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Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease.
Pearsall RS, Davies MV, Cannell M, Li J, Widrick J, Mulivor AW, Wallner S, Troy ME, Spaits M, Liharska K, Sako D, Castonguay R, Keates S, Grinberg AV, Suragani RNVS, Kumar R. Pearsall RS, et al. Among authors: suragani rnvs. Sci Rep. 2019 Aug 6;9(1):11392. doi: 10.1038/s41598-019-47818-w. Sci Rep. 2019. PMID: 31388039 Free PMC article.
ActRIIB:ALK4-Fc alleviates muscle dysfunction and comorbidities in murine models of neuromuscular disorders.
Li J, Fredericks M, Cannell M, Wang K, Sako D, Maguire MC, Grenha R, Liharska K, Krishnan L, Bloom T, Belcheva EP, Martinez PA, Castonguay R, Keates S, Alexander MJ, Choi H, Grinberg AV, Pearsall RS, Oh P, Kumar R, Suragani RN. Li J, et al. Among authors: suragani rn. J Clin Invest. 2021 Feb 15;131(4):e138634. doi: 10.1172/JCI138634. J Clin Invest. 2021. PMID: 33586684 Free PMC article.
16 results